Observational study on chronic uveitis in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on non-infectious chronic uveitis in pediatric patients, a rare inflammatory condition affecting the eye. It aims to establish a national registry in Italy to improve the diagnosis and management of this condition through a multidisciplinary approach involving ophthalmologists, rheumatologists, and infectious disease specialists. The study will collect data from various clinical centers to evaluate care quality and patient outcomes. By documenting cases, the study seeks to enhance understanding and treatment strategies for chronic uveitis in children.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* diagnosis of non-infectious chronic uveitis before the age of 16;
* signed informed consent form.

Exclusion Criteria:

* Patients with a diagnosis of infectious uveitis
* history of malignant pathology,
* history of demyelinating pathology,
* history of cerebral vasculitis

Where it's running

• Children's Mercy Kansas City Division of Rheumatology, Division of Rheumatology
  Kansas City, Kansas, United States Recruiting
• The Children's Hospital Corporation d/b/a Boston Children's Hospital
  Boston, Massachusetts, United States Recruiting
• Cincinnati Children's Hospital Medical Center
  Cincinnati, Ohio, United States Recruiting
• ATTIKON General Hospital
  Athens, Greece Recruiting
• Meyer Children's Hospital IRCCS
  Florence, Firenze, Italy Recruiting
• Department of Medical of Health Sciences, Magna Grecia University
  Catanzaro, Italy Recruiting

Study contacts

• Study coordinator: Gabriele Simonini
• Email: gabriele.simonini@meyer.it
• Phone: 3297973141

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Ocular Fluid Work-up in Presumed Trematode-Induced Granulomatous Uveitis

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• PANDA-ASOCT: Detecting Uveitis in Children with Automated Eye Image Analysis

  This study tests a high-speed, non-invasive eye imaging system with automated analysis to help detect uveitis in children and young people who attend a clinic for uveitis or juvenile idiopathic arthritis.

  Recruiting Sheffield Children's NHS Foundation Trust · Sheffield, South Yorkshire · NCT07813598

• GenSci048 vs placebo in active non-infectious uveitis

  This study tests whether GenSci048 can help people with active non-infectious uveitis compared with placebo.

  Recruiting Phase 2 Changchun GeneScience Pharmaceutical Co., Ltd. · Shanghai, Shanghai Municipality · NCT07547995

• Uveitis in children under 18

  This project collects medical information from children with uveitis to see how often different types occur and what treatments and clinical features look like.

  Recruiting at 4 sites Jaeb Center for Health Research · Boston, Massachusetts and 3 other locations · NCT07518134

• Metagenomic testing for infections in people with eye inflammation

  This project will test metagenomic sequencing on eye fluid to find infections in adults with unexplained ocular inflammation who are at risk of vision loss.

  Recruiting Moorfields Eye Hospital NHS Foundation Trust · London · NCT06974162

• Minocycline treatment for chronic autoimmune uveitis

  This study is testing if minocycline can help people aged 18-60 with chronic autoimmune uveitis reduce inflammation and protect their vision better than current treatments.

  Recruiting Phase 1/2 Sun Yat-sen University · Guangzhou, Guangdong · NCT05474729

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.