Investigating eye inflammation in survivors of Ebola virus disease
Official title: Pathogenesis of Uveitis in Ebola Virus Disease Survivors
Funded at University of Nebraska Medical Center · NIH-10667629 · Data updated 2026-11-12
This study is looking at how the Ebola virus can cause eye problems, specifically uveitis, in people who survived Ebola, to help improve their vision and overall well-being.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project start | July 1, 2019 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $511,328 |
| NIH project number | 5R01EY029594-06 |
| Project ID | NIH-10667629 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have survived Ebola virus disease and are experiencing symptoms of uveitis or other eye-related issues.
✕Less likely to help
Patients who have not been infected with the Ebola virus or who do not exhibit any eye-related symptoms may not benefit from this research.
What this research studies
This research focuses on understanding the causes and effects of uveitis, an eye condition, in individuals who have survived Ebola virus disease (EVD). It aims to characterize the clinical features and complications that lead to vision loss among EVD survivors, particularly following the West African outbreak from 2014-2016. The study employs advanced methodologies to analyze ocular fluid specimens for the presence of the Ebola virus and its impact on eye health. By exploring the relationship between the virus and uveitis, the research seeks to improve the quality of life for affected individuals.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of eye-related complications in Ebola survivors, potentially preserving vision and improving daily functioning.
How similar studies have gone: While the specific focus on uveitis in Ebola survivors is relatively novel, previous research has successfully explored the long-term health effects of Ebola virus disease, indicating potential for impactful findings.
Where this research is happening
-
University of Nebraska Medical Center
Omaha, United States Active
Researchers
- Principal investigator: Yeh, Steven — University of Nebraska Medical Center
- Study coordinator: Yeh, Steven
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.