Understanding motor recovery after stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Stroke Motor Rehabilitation and Recovery Study (SMaHRT) is a longitudinal observational study that aims to track the natural history of upper extremity motor recovery following ischemic and hemorrhagic strokes. Participants will be enrolled during their acute hospitalization and will undergo a series of research visits at various intervals post-stroke, including 6 weeks, 3 months, 6 months, one year, two years, and three years. The study will gather a wide range of data, including demographics, clinical outcomes, neuroimaging, and neurophysiological assessments, to better understand the factors influencing motor recovery and to develop personalized rehabilitation strategies. The ultimate goal is to enhance neurorehabilitation techniques and improve recovery outcomes for stroke patients.

Why it matters

Who can join: the full rules

Inclusion Criteria

* Age 18 - 90
* Upper extremity motor weakness after ischemic and/or hemorrhagic stroke as defined by a score of \>=1 on NIH Stroke Scale Arm Motor Drift Questions 5A or 5B
* Ability to follow simple commands in English
* Score of zero or 1 on the NIH Stroke Scale Level of Consciousness Questions 1a and 1b and a score of zero on the NIH Stroke Scale Level of Consciousness Question 1c.
* Stable medical status as determined by primary care team
* Inpatient on the MGH stroke neurology service

Exclusion Criteria

* Prior history of developmental, neurologic, or major psychiatric disorder resulting in functional disability
* Prior history of visual or auditory disorders limiting ability to participate in testing
* Evidence of an uncontrolled seizure disorder
* Patients for whom EEG leads are contraindicated

Where it's running

• Massachusetts General Hospital
  Boston, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: David J Lin, MD — Neurologist
• Study coordinator: Julie A DiCarlo, MS
• Email: jdicarlo2@mgh.harvard.edu
• Phone: 617-726-1311

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.