Longitudinal study on stroke recovery and biomarkers
FIND Stroke Recovery: A Longitudinal Frequent Evaluation Long-term Follow-up Study
This study looks at how stroke survivors recover over time by tracking their brain and thinking skills along with changes in their blood to see what helps them get better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 600 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Göteborg University Academic / other |
| Locations | 1 site (Gothenburg) |
| Trial ID | NCT05708807 on ClinicalTrials.gov |
What this trial studies
This observational study aims to understand the recovery trajectories of stroke survivors by monitoring neurological and cognitive functions alongside changes in blood biomarker concentrations. It will assess recovery patterns during the acute, subacute, and long-term phases following a first-ever ischemic stroke or intracerebral hemorrhage. By analyzing these profiles, the study seeks to identify individual variations in recovery and the mechanisms that contribute to stroke rehabilitation. Participants will be enrolled from the stroke units at Sahlgrenska University Hospital in Gothenburg, Sweden.
Who should consider this trial
Good fit: Ideal candidates include individuals experiencing their first-ever ischemic stroke or intracerebral hemorrhage.
Not a fit: Patients with severe neurodegenerative diseases or those unable to comply with study procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of stroke recovery and improve outcome predictions for patients.
How similar studies have performed: While studies on stroke recovery exist, this approach focusing on the temporal profiles of recovery and biomarker patterns is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Investigators enrol patients presenting with first-ever ischemic stroke or intracerebral haemorrhage admitted to the stroke units at the Sahlgrenska University Hospital in Gothenburg, Sweden. The inclusion criteria are: • first-ever acute ischemic stroke; or intracerebral hemorrhage. The exclusion criteria are: * pre-stroke mRS score of ≥3; * severe neurodegenerative disease, cerebral neoplasm or terminal illness; and * patients considered unlikely to be able to participate in or to understand and/or comply with study procedures during follow-up visits at the hospital.
Where this trial is running
Gothenburg
- Department of Neurology, Department of Neurorehabilitation and Department of Clinical Genetics, Sahlgrenska University Hospital — Gothenburg, Sweden (Recruiting)
Study contacts
- Principal investigator: Christina Jern, MD, PhD — Inst. of Biomedicine, the Sahlgrenska Academy, Univ. of Gothenburg
- Study coordinator: Christina Jern, MD, PhD
- Email: christina.jern@neuro.gu.se
- Phone: +46-31-3435720
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.