Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating how significant carotid stenosis affects retinal blood flow using automated oximetry

Official title: Impact of Significant Carotid Stenosis on Retinal Perfusion Measured Via Automated Retinal Oximetry

Run by University Hospital Olomouc · NCT06085612 · Data updated 2026-11-12

This study is testing how narrowing of the carotid artery affects blood flow in the retina to see if more severe narrowing leads to less blood flow.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment150 (estimated)
SponsorUniversity Hospital Olomouc
Academic / other
Locations1 site (Olomouc)
StatusRecruiting
StartedJanuary 1, 2023
Main results expectedJanuary 1, 2027
Study endsJanuary 1, 2028
Registry record updatedOctober 23, 2023
Trial IDNCT06085612 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients with significant carotid stenosis being examined at the University Hospital Olomouc, regardless of the reason for their examination.

Probably not a fit

Patients who are unable to undergo proper ophthalmological examinations, particularly those who cannot participate in automated retinal oximetry, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the impact of significant carotid stenosis on retinal perfusion through the use of automated retinal oximetry. By enrolling 50 patients annually, the study will analyze the relationship between the severity of carotid stenosis and changes in retinal blood flow. The hypothesis is that greater stenosis leads to reduced retinal perfusion, which may be indicated by higher arteriovenous saturation differences. This research could provide insights that expand the criteria for surgical revascularization in patients with carotid stenosis.

Why it matters

Potential benefit: If successful, this study could improve the evaluation and treatment options for patients with significant carotid stenosis, potentially reducing the risk of ischemic strokes.

How similar studies have gone: While the approach of using automated retinal oximetry in this context is relatively novel, similar studies have suggested potential benefits in understanding vascular health.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Study population will include patients examined in ultrasound laboratory in Neurology department of University Hospital Olomouc, regardless of incidental finding of stenosis, examination due to acute symptoms or regular checkup of known stenosis.

Exclusion Criteria:

* patients unable undergo ophthalmological examination properly, especially on automated retinal oximetry.

Where it's running

  • University Hospital Olomouc
    Olomouc, Czechia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.