Evaluating how significant carotid stenosis affects retinal blood flow using automated oximetry
Impact of Significant Carotid Stenosis on Retinal Perfusion Measured Via Automated Retinal Oximetry
University Hospital Olomouc · NCT06085612
This study is testing how narrowing of the carotid artery affects blood flow in the retina to see if more severe narrowing leads to less blood flow.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital Olomouc (other) |
| Locations | 1 site (Olomouc) |
| Trial ID | NCT06085612 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the impact of significant carotid stenosis on retinal perfusion through the use of automated retinal oximetry. By enrolling 50 patients annually, the study will analyze the relationship between the severity of carotid stenosis and changes in retinal blood flow. The hypothesis is that greater stenosis leads to reduced retinal perfusion, which may be indicated by higher arteriovenous saturation differences. This research could provide insights that expand the criteria for surgical revascularization in patients with carotid stenosis.
Who should consider this trial
Good fit: Ideal candidates include patients with significant carotid stenosis being examined at the University Hospital Olomouc, regardless of the reason for their examination.
Not a fit: Patients who are unable to undergo proper ophthalmological examinations, particularly those who cannot participate in automated retinal oximetry, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the evaluation and treatment options for patients with significant carotid stenosis, potentially reducing the risk of ischemic strokes.
How similar studies have performed: While the approach of using automated retinal oximetry in this context is relatively novel, similar studies have suggested potential benefits in understanding vascular health.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Study population will include patients examined in ultrasound laboratory in Neurology department of University Hospital Olomouc, regardless of incidental finding of stenosis, examination due to acute symptoms or regular checkup of known stenosis. Exclusion Criteria: * patients unable undergo ophthalmological examination properly, especially on automated retinal oximetry.
Where this trial is running
Olomouc
- University Hospital Olomouc — Olomouc, Czechia (RECRUITING)
Study contacts
- Study coordinator: Michal Král, MD., Ph.D.
- Email: michal.kral@fnol.cz
- Phone: +420604171594
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Stroke, Ischemic, Stenosis, Carotid, automated retinal oximetry