Rehabilitation program for lateropulsion after stroke using exoskeleton-assisted exercises

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study focuses on adults with a first right-hemisphere ischemic stroke who show moderate to severe lateropulsion. The approach combines exoskeleton-assisted lateral balance exercises with targeted physiotherapy to recalibrate verticality perception. The primary outcome is change in Visual Vertical orientation, measured repeatedly due to the small-sample design. Secondary aims include changes in postural perception of vertical and overall balance-related outcomes. Participants receive 15 sessions of 30 minutes over three weeks, alongside conventional rehabilitation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Right hemispheric first and unique ischemic stroke between 2 weeks and 6 months old (subacute phase) ;
* Presence of lateropulsion, assessed by the Scale for Contraversive Pushing (2 ≤ SCP \< 5)
* Presence of contralesional VV bias (VV \> 4°)
* Right handedness defined by a Edinburgh score ≥0,39
* Being hospitalized in a Physical Medicine and Neurological Rehabilitation (PMR) facility.
* Have given a written and informed consent

Exclusion Criteria:

* Medical instability making evaluation impossible,
* Comprehension or cognitive or behavioral disorders, or depressive symptoms that compromise participation in the program
* Postural disorders or body geometry disorders that interfere with balance for a reason that is independant of the stroke
* Morphological contraindications to the use of the Atalante® robot (segment length or joint ranges; height \<155cm; weight \>100kg),
* Severe spasticity (\>3 on the modified Ashworth scale) in the adductors, quadriceps, hamstrings and triceps surae
* Presence of a pressure sore at the areas of contact with the Atalante® robot,
* History of osteoporotic fractures.
* Pregnancy and breastfeeding

Where it's running

• Grenoble University Hospital
  Échirolles, France Recruiting
• Grenoble University Hospital
  Grenoble, France Recruiting

Study contacts

• Principal investigator: Dominic Pérennou, MD, PhD, Pr — University Hospital, Grenoble
• Study coordinator: Dominic Pérennou, MD, PhD, Pr
• Email: dperennou@chu-grenoble.fr
• Phone: +334 76 76 60 83

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.