Condition

Respiratory Disease clinical trials and research

• 14Clinical trials
• 28NIH research projects
• 10Countries

Newest Respiratory Disease clinical trials

All recruiting trials (14)

• Multicenter chest X-ray screening for thoracic diseases

  This project will test whether routine chest X-rays can detect thoracic problems in adults who come for routine health examinations.

  Recruiting Chinese Academy of Sciences · Dazhou, Sichuan · NCT07585214

• Teaching bronchoscopy skills using glove sensors, videos, and CT scans

  This project will test whether collecting CT scans, bronchoscopy videos, and hand-motion data from up to 300 patients and about 20 bronchoscopists can help teach bronchoscopy skills.

  Recruiting University of Edinburgh · Edinburgh · NCT07168408

• Assessing respiratory dysfunction and frailty in allergic and eosinophilic asthma patients

  This study is trying to see how breathing problems and fatigue affect people with allergic and eosinophilic asthma, to help create better treatment plans for them.

  Recruiting Hacettepe University · Ankara, State · NCT06796894

• Examining respiratory outcomes in extremely preterm infants

  This study looks at how being born very early affects the breathing of preterm babies over their first two years to help improve their care.

  Recruiting Seoul National University Hospital · Seoul · NCT06726226

• A portable, easy-to-use CPAP device for non-invasive breathing support.

  This will test a new portable CPAP device to see if older adults and hospitalized patients with low oxygen can use it easily and whether it helps them breathe better.

  Recruiting Università Vita-Salute San Raffaele · Lecce, Apulia and 2 other locations · NCT06716502

• Evaluation of the INSPIRE Respiratory Health Program in Botucatu, Brazil

  This study is testing the INSPIRE program to see how well it helps adults with respiratory issues in Botucatu manage their health and access care over five years.

  Recruiting UPECLIN HC FM Botucatu Unesp · Botucatu, São Paulo · NCT06673225

• Benefits of Osteopathic Manual Therapy for Patients with Respiratory Illness

  This study is testing if adding Osteopathic Manual Therapy to standard care can help older patients with respiratory illnesses like pneumonia and bronchitis feel better faster.

  Recruiting Geisinger Clinic · Bloomsburg, Pennsylvania · NCT06495021

• Investigating the connection between gut and lung health in children

  This study is trying to see how gut health affects lung health in children with breathing or stomach problems compared to those who are healthy.

  Recruiting NHS Greater Glasgow and Clyde · Glasgow · NCT06271213

• Caffeine treatment for late preterm infants with breathing difficulties

  This study tests if giving caffeine to late preterm infants with breathing problems can help them breathe better and shorten their hospital stay.

  Recruiting at 2 sites Phase 2/3 Ministry of Health, Saudi Arabia · Madinah, Medina Region and 1 other locations · NCT06026163

• Standardized oral care using human milk for premature infants in the NICU

  This study is trying to see if giving regular oral care using human milk can help very low birth weight babies in the NICU stay healthier and avoid complications.

  Recruiting University of Florida · Gainesville, Florida · NCT06000761

• Characterizing patients treated at internal medicine clinics

  This study looks at patients with serious health issues treated in internal medicine clinics to see how their different conditions affect their care and to find better ways to diagnose and treat them.

  Recruiting at 2 sites IRCCS San Raffaele · Milan and 1 other locations · NCT05780099

• Registry for measuring respiratory health in children

  This study is collecting information on lung health in children, especially those with cystic fibrosis and other breathing issues, to see how well a new testing method works compared to standard tests.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT05501587

• Registry for imaging measures of respiratory health

  This study is collecting information on lung health using advanced MRI scans to see how well lungs work in both healthy people and those with breathing problems.

  Recruiting at 2 sites University of British Columbia · Vancouver, British Columbia and 1 other locations · NCT05102825

• A large health study in Hamburg focusing on chronic diseases

  This study is trying to find out what causes chronic diseases by looking at the health and lifestyle of 45,000 people aged 45 to 74 in Hamburg, Germany, and checking in with them over time.

  Recruiting Universitätsklinikum Hamburg-Eppendorf · Hamburg · NCT03934957

NIH-funded research (28)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Household air pollution and child DNA changes tied to later lung health

  A study in Guatemalan children looks at how early exposure to smoky kitchen fuel changes DNA and could influence respiratory health as they grow.

  NIH research University of Georgia · Athens, United States · NIH-11509226

• Genetic testing and specialist care for rare causes of chronic lung, sinus, and ear infections

  This project offers stepwise genetic testing and specialty referrals to find rare inherited causes of recurring lung, sinus, and ear infections in children and adults.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11472359

• Quantitative imaging to find chronic lung disease in high-risk patients

  A project will use advanced chest CT image analysis to detect chronic lung diseases early in veterans, aiming to help people who might otherwise go undiagnosed.

  NIH research Minneapolis VA Medical Center · Minneapolis, United States · NIH-11449286

• Understanding lung diseases by combining genetic data and big biobank information

  A big research project will look at genes, health data, and other biological information from diverse people to better understand why COPD and asthma develop and vary across populations.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11414911

• Early-life household air pollution and DNA changes linked to childhood respiratory health in Guatemalan kids

  This study looks at how exposure to smoke from solid fuel at home in early life may affect DNA and respiratory health in Guatemalan children enrolled in the HAPIN trial.

  NIH research University of Georgia · Athens, United States · NIH-11411148

• Long-term endotypes of prematurity-related lung disease in former preemies

  A long-term study looking at why some babies born very early develop lasting breathing problems and how their genes might explain these different paths.

  NIH research Lurie Children's Hospital of Chicago · Chicago, United States · NIH-11404818

• Integrating real-world data to better predict respiratory disease spread

  A research team at Georgetown University is using real-world data to build models that better predict how respiratory diseases spread over time and across places, helping policymakers and clinicians plan better responses.

  NIH research Georgetown University · Washington, United States · NIH-11401097

• Air pollution and death risk in veterans with lung disease

  A patient-facing team will study how air pollution affects death risk in people with chronic lung diseases, especially among veterans.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11395536

• Environmental acquisition of livestock-associated Staphylococcus aureus in people with chronic lung disease

  This project explores whether a livestock-linked Staphylococcus aureus strain (ST398) found in a small group of people with cystic fibrosis can persist and come from environmental sources like food or water.

  NIH research University of Iowa · Iowa City, United States · NIH-11378686

• Aspirin-Exacerbated Respiratory Disease: How it develops and how we might treat it

  This project studies why aspirin-triggered respiratory disease happens and tests potential ways to reduce its airway inflammation.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11351995

• How cell signals shape HPV-related airway papillomas and vaccine response

  This project looks at why some people with recurrent respiratory papillomatosis (caused by HPV 6/11) respond to the PRGN-2012 vaccine while others do not by examining viral and cellular signals in their lesions and blood.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11309147

• Tiered genetic testing and specialist referrals for rare causes of chronic ear, sinus, and lung infections

  This project offers stepwise genetic testing and specialist referrals to find rare inherited causes of persistent ear, sinus, and lung infections in children and adults.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11257668

• Predicting nasal polyp return in people with aspirin-exacerbated respiratory disease

  This project looks for proteins and immune signals in nasal tissue and mucus that could predict whether nasal polyps will come back after surgery and aspirin desensitization in adults with aspirin-exacerbated respiratory disease.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11252885

• Long-term lung health after very early birth

  This project looks for genetic patterns that explain why some babies born before 28 weeks have lasting breathing problems, to help people born very prematurely.

  NIH research Lurie Children's Hospital of Chicago · Chicago, United States · NIH-11168722

• Air pollution effects for veterans with chronic lung disease

  This project looks at whether short-term rises in fine particles (PM2.5) and ozone increase the risk of death for veterans with chronic lung diseases and which personal or neighborhood factors make that risk higher.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11163215

• Investigating how Staphylococcus aureus and eicosanoids contribute to inflammation in aspirin-exacerbated respiratory disease.

  This study is looking at how a common germ in nasal polyps might affect inflammation in people with aspirin-exacerbated respiratory disease (AERD), with the goal of finding better ways to diagnose and treat this condition.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11132942

• Analyzing asthma and respiratory disease data from national health surveys

  This study looks at health data to find out how things like allergens and air pollution affect asthma and breathing problems, so we can help improve treatments and health policies for people with these conditions.

  NIH research Social and Scientific Systems, INC. · Silver Spring, United States · NIH-11122158

• How Pseudomonas aeruginosa evolves in plumbing and affects cystic fibrosis

  This study looks at how a germ called Pseudomonas aeruginosa, which can cause serious lung infections, changes and grows in building plumbing, especially to help protect people with cystic fibrosis from getting sick.

  NIH research Carnegie-Mellon University · Pittsburgh, United States · NIH-11082322

• Understanding how HPV affects respiratory disease and vaccine response

  This study is looking at how certain cells and viruses affect the way people with recurrent respiratory papillomatosis (RRP) respond to a new HPV vaccine, with the goal of finding better ways to help those who aren't getting better with current treatments.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11074859

• Understanding and Treating Aspirin-Exacerbated Respiratory Conditions

  This research aims to understand why some people with asthma and nasal polyps react badly to aspirin, hoping to find better ways to help them.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11067831

• Identifying markers that predict nasal polyp recurrence in patients with aspirin-related respiratory issues

  This study is looking at how certain biological markers in your body can help predict if nasal polyps will come back after surgery and aspirin treatment for those with aspirin-exacerbated respiratory disease (AERD), so that doctors can better tailor treatments for you.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11056424

• CT scan analysis to spot early chronic lung disease

  This project uses computer analysis of chest CT scans to find early signs of COPD and other long-term lung diseases in veterans and people at high risk.

  NIH research VA Boston Health Care System · Boston, United States · NIH-11044097

• Training scientists to improve respiratory health

  This study is all about helping scientists learn how to improve treatments for people with breathing problems by combining different types of research and working together with experts from various fields.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11013483

• Identifying genetic causes of chronic respiratory diseases

  This study is looking to help people with ongoing respiratory issues, like frequent sinus infections and bronchitis, by using genetic testing to find out if there are any genetic reasons behind their conditions, which could lead to better ways to manage and prevent these problems.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11011339

• The impact of air pollution on veterans with chronic respiratory diseases.

  This study looks at how air pollution impacts veterans with breathing problems like asthma and COPD, aiming to find out which veterans are most affected based on their age, gender, and where they live, so we can better protect those who are at risk.

  NIH research University of Minnesota · Minneapolis, United States · NIH-10855504

• Understanding long-term respiratory issues in premature infants

  This study is looking at how being born very early affects breathing problems like asthma in babies, and it’s for families of premature infants who want to understand and help prevent these issues as their children grow up.

  NIH research Lurie Children's Hospital of Chicago · Chicago, United States · NIH-10804513

• Investigating how air pollution affects children's hospitalizations for respiratory diseases in New York State

  This study looks at how air pollution in neighborhoods affects kids under 12 with breathing problems in New York, aiming to find ways to keep our children healthier by understanding the impact of dirty air on their lungs.

  NIH research Temple Univ of the Commonwealth · Philadelphia, United States · NIH-10784440

• Exploring new treatments for breathing problems related to obesity

  This study is looking at how the brain affects breathing problems in people with obesity, especially those with Obesity Hypoventilation Syndrome, to find new ways to help them breathe better.

  NIH research Marquette University · Milwaukee, United States · NIH-10730653

Related topics

Quick answers

How many Respiratory Disease clinical trials are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in Italy (2 trials), United Kingdom (2 trials), Canada (2 trials), United States (2 trials), Saudi Arabia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →