A large health study in Hamburg focusing on chronic diseases
Official title: A Single Center, Prospective, Epidemiologic Cohort Study With Emphasis on Imaging to Improve the Identification of Individuals at Risk for Major Chronic Diseases and to Improve Early Diagnosis and Survival
Run by Universitätsklinikum Hamburg-Eppendorf · NCT03934957 · Data updated 2026-11-12
This study is trying to find out what causes chronic diseases by looking at the health and lifestyle of 45,000 people aged 45 to 74 in Hamburg, Germany, and checking in with them over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 45 Years to 74 Years |
| Sex | All |
| Enrollment | 45000 (estimated) |
| Sponsor | Universitätsklinikum Hamburg-Eppendorf Academic / other |
| Locations | 1 site (Hamburg) |
| Status | Recruiting |
| Started | February 8, 2016 |
| Main results expected | December 31, 2022 |
| Study ends | December 31, 2028 |
| Registry record updated | May 2, 2019 |
| Trial ID | NCT03934957 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are residents of Hamburg aged 45 to 74 who can provide informed consent.
✕Probably not a fit
Patients who are not fluent in German or have physical or psychological limitations preventing participation may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The Hamburg City Health Study is a long-term, population-based cohort study involving 45,000 participants aged 45 to 74 from Hamburg, Germany. Participants will undergo extensive baseline assessments, including validated examinations targeting cardiac, vascular, and cerebral functions, along with lifestyle and health history evaluations. The study aims to identify risk factors for chronic diseases and develop predictive models for health outcomes based on a wide range of data, including genomic and proteomic information. Follow-up examinations will be conducted to assess health outcomes over time.
Why it matters
Potential benefit: If successful, this study could lead to improved prevention and management strategies for chronic diseases such as coronary heart disease, stroke, and dementia.
How similar studies have gone: Other large cohort studies have successfully identified risk factors for chronic diseases, suggesting that this approach is promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Inhabitant of the city of Hamburg at the time of inclusion into the study (Inclusion is time of written consent) * Age 45 to 74 years * Personally signed informed consent Exclusion Criteria: * Insufficient knowledge of the German language, in order to understand study documents and computer assisted interview without translation * Physical or psychological incapability to travel to the study center and to cooperate in the investigations
Where it's running
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Universitätsklinikum Hamburg-Eppendorf
Hamburg, Germany Recruiting
Study contacts
- Principal investigator: Stefan Blankenberg, Professor — Universitäres Herzzentrum Hamburg
- Study coordinator: Annika Jagodzinski, MD
- Email: A.Jagodzinski@uke.de
- Phone: 0049741059328
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.