A large health study in Hamburg focusing on chronic diseases

A Single Center, Prospective, Epidemiologic Cohort Study With Emphasis on Imaging to Improve the Identification of Individuals at Risk for Major Chronic Diseases and to Improve Early Diagnosis and Survival

Observational Universitätsklinikum Hamburg-Eppendorf · NCT03934957

This study is trying to find out what causes chronic diseases by looking at the health and lifestyle of 45,000 people aged 45 to 74 in Hamburg, Germany, and checking in with them over time.

Quick facts

Study typeObservational
Enrollment45000 (estimated)
Ages45 Years to 74 Years
SexAll
SponsorUniversitätsklinikum Hamburg-Eppendorf Academic / other
Locations1 site (Hamburg)
Trial IDNCT03934957 on ClinicalTrials.gov

What this trial studies

The Hamburg City Health Study is a long-term, population-based cohort study involving 45,000 participants aged 45 to 74 from Hamburg, Germany. Participants will undergo extensive baseline assessments, including validated examinations targeting cardiac, vascular, and cerebral functions, along with lifestyle and health history evaluations. The study aims to identify risk factors for chronic diseases and develop predictive models for health outcomes based on a wide range of data, including genomic and proteomic information. Follow-up examinations will be conducted to assess health outcomes over time.

Who should consider this trial

Good fit: Ideal candidates are residents of Hamburg aged 45 to 74 who can provide informed consent.

Not a fit: Patients who are not fluent in German or have physical or psychological limitations preventing participation may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved prevention and management strategies for chronic diseases such as coronary heart disease, stroke, and dementia.

How similar studies have performed: Other large cohort studies have successfully identified risk factors for chronic diseases, suggesting that this approach is promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Inhabitant of the city of Hamburg at the time of inclusion into the study (Inclusion is time of written consent)
* Age 45 to 74 years
* Personally signed informed consent

Exclusion Criteria:

* Insufficient knowledge of the German language, in order to understand study documents and computer assisted interview without translation
* Physical or psychological incapability to travel to the study center and to cooperate in the investigations

Where this trial is running

Hamburg

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Coronary Heart DiseaseStrokeDementiaCancerHealth CareVascular DiseasesPeriodontal DiseasesOcular Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.