Examining respiratory outcomes in extremely preterm infants
Multicenter Cohort for Respiratory Outcome of Preterm Infants
Seoul National University Hospital · NCT06726226
This study looks at how being born very early affects the breathing of preterm babies over their first two years to help improve their care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 600 (estimated) |
| Ages | N/A to 7 Days |
| Sex | All |
| Sponsor | Seoul National University Hospital (other) |
| Locations | 1 site (Seoul) |
| Trial ID | NCT06726226 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the respiratory outcomes of preterm infants born at less than 29 weeks of gestation, tracking their progress from birth to 24 months corrected age. It focuses on identifying neonatal and perinatal factors that contribute to respiratory function impairment and chronic respiratory diseases. The study aims to enhance treatment and prevention strategies by analyzing various influences, including respiratory distress syndrome and nutritional aspects during NICU stays. By synthesizing data on respiratory health and developmental outcomes, the research seeks to improve care for this vulnerable population.
Who should consider this trial
Good fit: Ideal candidates for this study are infants born at gestational ages less than 29 weeks whose parents provide consent within 7 days of birth.
Not a fit: Patients who may not benefit from this study include those who die within 3 days of birth or have severe structural heart defects or congenital anomalies affecting cardiopulmonary function.
Why it matters
Potential benefit: If successful, this study could lead to improved prevention and treatment strategies for chronic respiratory diseases in preterm infants.
How similar studies have performed: Other cohorts, such as the PROP cohort in the U.S. and the Saitama cohort in Japan, have shown success in similar approaches, indicating a potential for valuable insights from this study.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Infants born at gestational age less than 29 weeks with cohort consent obtained within 7 days of birth Exclusion Criteria: * death within 3 days of birth * severe structural heart defects * structural abnormalities in the upper airway, lungs, or chest * congenital anomalies that may impact cardiopulmonary function * follow-up is difficult until 24 months of age
Where this trial is running
Seoul
- Seung Han Shin — Seoul, South Korea (RECRUITING)
Study contacts
- Principal investigator: Seung Han Shin, MD, PhD — Seoul National University Children's Hospital
- Study coordinator: Seung Han Shin, MD, PhD
- Email: revival421@snu.ac.kr
- Phone: +82-02-2072-7230
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Infant, Premature, Respiratory Disease