Clinical trial Recruiting at 1 site Observational Ages Any age to 7 Days

Examining respiratory outcomes in extremely preterm infants

Official title: Multicenter Cohort for Respiratory Outcome of Preterm Infants

Run by Seoul National University Hospital · NCT06726226 · Data updated 2026-11-12

This study looks at how being born very early affects the breathing of preterm babies over their first two years to help improve their care.

Quick facts

Study typeObservational
AgesAny age to 7 Days
SexAll
Enrollment600 (estimated)
SponsorSeoul National University Hospital
Academic / other
Locations1 site (Seoul)
StatusRecruiting
StartedJune 1, 2022
Main results expectedFebruary 28, 2030
Study endsFebruary 28, 2030
Registry record updatedDecember 10, 2024
Trial IDNCT06726226 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are infants born at gestational ages less than 29 weeks whose parents provide consent within 7 days of birth.

Probably not a fit

Patients who may not benefit from this study include those who die within 3 days of birth or have severe structural heart defects or congenital anomalies affecting cardiopulmonary function.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the respiratory outcomes of preterm infants born at less than 29 weeks of gestation, tracking their progress from birth to 24 months corrected age. It focuses on identifying neonatal and perinatal factors that contribute to respiratory function impairment and chronic respiratory diseases. The study aims to enhance treatment and prevention strategies by analyzing various influences, including respiratory distress syndrome and nutritional aspects during NICU stays. By synthesizing data on respiratory health and developmental outcomes, the research seeks to improve care for this vulnerable population.

Why it matters

Potential benefit: If successful, this study could lead to improved prevention and treatment strategies for chronic respiratory diseases in preterm infants.

How similar studies have gone: Other cohorts, such as the PROP cohort in the U.S. and the Saitama cohort in Japan, have shown success in similar approaches, indicating a potential for valuable insights from this study.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Infants born at gestational age less than 29 weeks with cohort consent obtained within 7 days of birth

Exclusion Criteria:

* death within 3 days of birth
* severe structural heart defects
* structural abnormalities in the upper airway, lungs, or chest
* congenital anomalies that may impact cardiopulmonary function
* follow-up is difficult until 24 months of age

Where it's running

  • Seung Han Shin
    Seoul, South Korea
    Recruiting

Study contacts

  • Principal investigator: Seung Han Shin, MD, PhD — Seoul National University Children's Hospital
  • Study coordinator: Seung Han Shin, MD, PhD
  • Email: revival421@snu.ac.kr
  • Phone: +82-02-2072-7230

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.