Quantitative imaging to find chronic lung disease in high-risk patients
Official title: Quantitative Imaging Analysis to Identify Chronic Respiratory Disease
Funded at Minneapolis VA Medical Center · NIH-11449286 · Data updated 2026-11-12
A project will use advanced chest CT image analysis to detect chronic lung diseases early in veterans, aiming to help people who might otherwise go undiagnosed.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Minneapolis VA Medical Center NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | January 1, 2022 |
| Project end | December 31, 2027 |
| Funding year | 2027 |
| NIH project number | 5I01CX002193-05 |
| Project ID | NIH-11449286 on NIH RePORTER |
Who could benefit from this research
✓Could help
Veterans undergoing chest CT screening who are at high risk for chronic respiratory diseases and have no prior diagnosis of CRD.
✕Less likely to help
Individuals without CRD risk factors or those whose scans do not show chronic changes may not benefit.
What this research studies
This project focuses on using quantitative imaging analysis of chest CT scans to identify chronic respiratory diseases such as COPD and ILD in a high-risk veteran population. By applying objective, automated measurements, the effort seeks to overcome variability in human interpretation and capture chronic changes beyond what is usually reported. The goal is to enable earlier diagnosis and potentially earlier medical management to improve outcomes. The study leverages existing lung cancer screening CT data within a structured program to uncover undiagnosed CRDs.
Why it matters
Potential benefit: If successful, patients could receive earlier detection of chronic lung diseases and timely care that may slow progression and improve quality of life.
How similar studies have gone: Previous work shows that quantitative imaging can reveal disease patterns not captured by standard reports, suggesting potential for meaningful detection improvements.
Where this research is happening
-
Minneapolis VA Medical Center
Minneapolis, United States Active
Researchers
- Principal investigator: Wan, Emily S — Minneapolis VA Medical Center
- Study coordinator: Wan, Emily S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.