Skin conductance to predict low blood pressure after spinal anesthesia in older urologic cancer patients
Official title: Skin Conductance as a Predictor of Spinal Anesthesia-Induced Hypotension in Geriatric Oncology Patients
Run by Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · NCT07481851 · Data updated 2026-11-12
This project will try to see if skin conductance monitoring can predict which patients aged 65 and older having urologic cancer surgery with spinal anesthesia will develop low blood pressure.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 102 (estimated) |
| Sponsor | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Academic / other |
| Locations | 1 site (Ankara, Yenimahalle) |
| Status | Recruiting |
| Started | December 22, 2025 |
| Main results expected | April 1, 2026 |
| Study ends | May 1, 2026 |
| Registry record updated | March 25, 2026 |
| Trial ID | NCT07481851 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients 65 years or older scheduled for elective urologic oncology surgery under spinal anesthesia with ASA physical status I–III who can provide written informed consent.
✕Probably not a fit
Patients with contraindications to spinal anesthesia, severe autonomic dysfunction or neuropathy, implanted pacemakers, medications that markedly affect autonomic activity, baseline hemodynamic instability, or skin problems preventing reliable electrode placement are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective observational protocol in which continuous skin conductance recordings will be obtained alongside standard perioperative blood pressure and heart rate measurements in geriatric patients undergoing elective urologic oncology surgery with spinal anesthesia. The study will enroll patients aged 65 and older with ASA physical status I–III who provide informed consent and will not introduce any experimental therapies beyond noninvasive monitoring. Investigators will analyze temporal correlations between changes in skin conductance and subsequent hypotension events to identify predictive patterns. Findings will determine whether skin conductance signals reliably precede spinal anesthesia–induced hypotension in this vulnerable population.
Why it matters
Potential benefit: If successful, clinicians could detect patients at imminent risk of spinal anesthesia–induced hypotension earlier and intervene to reduce complications.
How similar studies have gone: Some prior work links skin conductance to sympathetic activity in pain and stress settings, but using it to predict spinal anesthesia–induced hypotension in elderly urologic oncology patients is largely novel and unproven.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 65 years and older * Patients scheduled for elective urologic oncology surgery under spinal anesthesia * American Society of Anesthesiologists (ASA) physical status I-III * Patients who provide written informed consent to participate in the study Exclusion Criteria: * Refusal to participate or inability to provide informed consent * Contraindication to spinal anesthesia (e.g., infection at puncture site, coagulopathy) * Severe cardiac conduction abnormalities or presence of a cardiac pacemaker * Severe autonomic dysfunction or known neuropathy affecting autonomic responses * Use of medications that significantly affect autonomic nervous system activity * Baseline hypotension or hemodynamic instability before spinal anesthesia * Inability to obtain reliable skin conductance measurements (e.g., severe skin lesions at electrode placement site)
Where it's running
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Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital Clinic of Anesthesiology and Rea
Ankara, Yenimahalle, Turkey (Türkiye) Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.