Skin conductance to predict low blood pressure after spinal anesthesia in older urologic cancer patients
Skin Conductance as a Predictor of Spinal Anesthesia-Induced Hypotension in Geriatric Oncology Patients
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · NCT07481851
This project will try to see if skin conductance monitoring can predict which patients aged 65 and older having urologic cancer surgery with spinal anesthesia will develop low blood pressure.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 102 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital (other) |
| Locations | 1 site (Ankara, Yenimahalle) |
| Trial ID | NCT07481851 on ClinicalTrials.gov |
What this trial studies
This is a prospective observational protocol in which continuous skin conductance recordings will be obtained alongside standard perioperative blood pressure and heart rate measurements in geriatric patients undergoing elective urologic oncology surgery with spinal anesthesia. The study will enroll patients aged 65 and older with ASA physical status I–III who provide informed consent and will not introduce any experimental therapies beyond noninvasive monitoring. Investigators will analyze temporal correlations between changes in skin conductance and subsequent hypotension events to identify predictive patterns. Findings will determine whether skin conductance signals reliably precede spinal anesthesia–induced hypotension in this vulnerable population.
Who should consider this trial
Good fit: Ideal candidates are patients 65 years or older scheduled for elective urologic oncology surgery under spinal anesthesia with ASA physical status I–III who can provide written informed consent.
Not a fit: Patients with contraindications to spinal anesthesia, severe autonomic dysfunction or neuropathy, implanted pacemakers, medications that markedly affect autonomic activity, baseline hemodynamic instability, or skin problems preventing reliable electrode placement are unlikely to benefit.
Why it matters
Potential benefit: If successful, clinicians could detect patients at imminent risk of spinal anesthesia–induced hypotension earlier and intervene to reduce complications.
How similar studies have performed: Some prior work links skin conductance to sympathetic activity in pain and stress settings, but using it to predict spinal anesthesia–induced hypotension in elderly urologic oncology patients is largely novel and unproven.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 65 years and older * Patients scheduled for elective urologic oncology surgery under spinal anesthesia * American Society of Anesthesiologists (ASA) physical status I-III * Patients who provide written informed consent to participate in the study Exclusion Criteria: * Refusal to participate or inability to provide informed consent * Contraindication to spinal anesthesia (e.g., infection at puncture site, coagulopathy) * Severe cardiac conduction abnormalities or presence of a cardiac pacemaker * Severe autonomic dysfunction or known neuropathy affecting autonomic responses * Use of medications that significantly affect autonomic nervous system activity * Baseline hypotension or hemodynamic instability before spinal anesthesia * Inability to obtain reliable skin conductance measurements (e.g., severe skin lesions at electrode placement site)
Where this trial is running
Ankara, Yenimahalle
- Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital Clinic of Anesthesiology and Rea — Ankara, Yenimahalle, Turkey (Türkiye) (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Hypotension, Urologic Neoplasms, Aged, Spinal Anesthesia