Condition

Bradycardia clinical trials and research

• 38Clinical trials
• 1NIH research projects
• 44Countries

Newest Bradycardia clinical trials

All recruiting trials (38)

• SPIKE FLOW endocardial pacing lead safety and performance study

  This study tests whether the SPIKE FLOW temporary endocardial pacing lead is safe and effective in adults needing temporary pacing during heart-related conditions.

  Recruiting at 2 sites FIAB SpA · Acquaviva delle Fonti, Bari and 2 other locations · NCT07820072

• Factors Linked to Slow Heart Rate After Pulsed Field Ablation for Atrial Fibrillation

  This study looks for factors that might cause bradycardia during the hospital stay after AF ablation using pulsed field technology.

  Recruiting Wroclaw Medical University · Wroclaw, Lower Silesian Voivodeship · NCT07809347

• Transjugular implantation of a leadless pacemaker (Aveir VR) for ventricular pacing

  This study tests whether placing an Aveir VR leadless pacemaker through the neck vein can safely provide ventricular pacing in adults with bradycardia.

  Recruiting Xijing Hospital · Xi'an, Shaanxi · NCT07802119

• Conduction System Pacing Display Research During LBBAP Implant

  Researchers are testing a CSP Display System during left bundle branch area pacing pacemaker implant to see if it accurately shows heart signals compared with a standard ECG.

  Recruiting at 2 sites Medtronic Cardiac Rhythm and Heart Failure · Madurai, Tamil Nadu and 1 other locations · NCT07733960

• Focal Cryoablation vs. Radiofrequency Cardioneuroablation for Bradyarrhythmias

  This study tests whether focal cryoablation can treat vagally driven slow heart rhythms as well as traditional radiofrequency ablation in adults with bradycardia or related syncope.

  Recruiting Tomsk National Research Medical Center of the Russian Academy of Sciences · Tomsk, Tomsk Oblast · NCT07671898

• Personalized pacing rate to see if higher lower rate helps heart and brain flow

  In hypertensive patients with bradycardia who need a dual-chamber pacemaker, the study tests whether setting a higher, personalized pacing rate improves heart function and brain blood flow compared with the standard 60 bpm.

  Recruiting Medtronic Cardiac Rhythm and Heart Failure · Taiyuan, Shanxi · NCT07589452

• Permanent Conduction System Pacing vs Native Conduction in Wide QRS with Intermittent Bradycardia

  This study tests whether conduction system pacing can better preserve heart function than native conduction in adults with wide QRS and intermittent bradycardia who need a pacemaker.

  Recruiting at 3 sites Spanish Society of Cardiology · Granada, Andalusia and 2 other locations · NCT07585799

• Personalized pacemaker rate setting to improve symptoms in heart failure with bradycardia

  Researchers will try adjusting the pacemaker lower rate to a personalized, hemodynamically optimized heart rate to see if it reduces symptoms in people with heart failure who need a pacemaker.

  Recruiting Samsung Medical Center · Seoul, Seoul · NCT07563153

• Sedation with dexmedetomidine, propofol, or both during cataract surgery

  This project will test whether dexmedetomidine, propofol, or their combination (each given with fentanyl) provides the best sedation, safety, and surgeon satisfaction for adults having cataract surgery.

  Recruiting Saint-Joseph University · Beirut · NCT07556133

• HeartBeam ECG Registry: See How Heartbeat Patterns Look Across People

  This registry tests HeartBeam ECG recordings in real-world patients to build a de-identified database for research.

  Recruiting HeartBeam, Inc. · Pittsburgh, Pennsylvania · NCT07501299

• BIOTRONIK CSP Lead Registry for Left Bundle Branch Area Pacing

  This registry tests BIOTRONIK’s CSP-based pacing lead in patients needing a pacemaker or CRT, to see how it performs in real-life use.

  Recruiting at 12 sites Biotronik SE & Co. KG · Adelaide and 45 other locations · NCT07393009

• LINEA pacing lead for septal placement in pacemaker patients

  This study tests the safety and performance of a new LINEA cardiac pacing lead for patients getting a new pacemaker with septal placement.

  Recruiting at 14 sites MicroPort CRM · Ghent and 13 other locations · NCT07342608

• Dexmedetomidine versus dexamethasone added to ropivacaine for supraclavicular nerve block in upper‑limb surgery

  This test compares two medicines added to ropivacaine to see which gives faster onset and longer pain relief for adults having upper‑limb surgery with an ultrasound‑guided supraclavicular nerve block.

  Recruiting Phase 2/3 Sahiwal medical college sahiwal · Sāhīwāl, Punjab Province · NCT07290595

• Leadless Conduction System Pacemaker for Chronic Bradycardia

  This study tests a leadless AVEIR CSP pacemaker to see if it safely and reliably keeps heart rhythm in adults who need a pacemaker.

  Recruiting Abbott Medical Devices · Prague · NCT07287423

• Supra- versus infra-inguinal fascia iliaca blocks for easier spinal positioning and pain relief in lower limb surgery

  This test will compare two ultrasound-guided fascia iliaca nerve blocks to see which helps adults aged 30–60 with thigh or knee fractures have less pain and easier positioning for spinal anesthesia.

  Recruiting Phase 2/3 Sahiwal medical college sahiwal · Sāhīwāl, Punjab Province · NCT07221682

• Left bundle branch area pacing with Tendril STS or UltiPace leads

  This study will try left bundle branch area pacing with the Tendril STS or UltiPace lead in adults who need pacemaker leads for bradycardia or related heart conditions to see if pacing and sensing are safe and work through six months after implant.

  Recruiting at 13 sites Abbott Medical Devices · Rio de Janeiro, Rio de Janeiro and 14 other locations · NCT07217392

• LivIQ leadless pacemaker system for ventricular pacing

  This trial will test the LivIQ leadless pacemaker in adults who need ventricular pacing (VVI or VDD) to see if it is safe and maintains appropriate heart rhythm and AV timing.

  Recruiting at 41 sites Biotronik, Inc. · Burlingame, California and 42 other locations · NCT07118358

• Kardi Ai ECG telemetry monitoring for detecting heart rhythm problems

  The Kardi Ai wearable ECG system will be tested to see if it can accurately detect irregular heart rhythms in adults with or suspected of having heart rhythm disorders.

  Recruiting at 2 sites KARDI AI Technologies s.r.o. · Olomouc, Czechia and 1 other locations · NCT07018648

• AVEIR leadless pacemaker registry in the United Kingdom

  This project will follow people in the UK who receive an AVEIR leadless pacemaker to see how well the device works and how safe it is over five years.

  Recruiting Royal Brompton & Harefield NHS Foundation Trust · London, UK and 1 other locations · NCT06854484

• Ultra-high-frequency ECG to diagnose ventricular electrical dyssynchrony in patients getting pacemakers

  This test checks whether an ultra-high-frequency ECG can safely and accurately detect ventricular dyssynchrony in adults with bradycardia or heart failure who are having their first pacemaker implanted.

  Recruiting at 12 sites VDI Technologies · Avondale, Arizona and 11 other locations · NCT06641362

• Comparing two types of nerve blocks for pain relief in femur fracture surgery

  This study is testing which of two types of nerve blocks can provide better pain relief for patients having surgery for femur fractures.

  Recruiting Phase 2/3 Sahiwal medical college sahiwal · Sahiwal, Punjab Province · NCT06568770

• Effect of phosphocreatine on patients treated by medical emergency teams

  This study tests if giving phosphocreatine to hospitalized patients with serious conditions can help them recover faster and shorten their hospital stays compared to those who receive a placebo.

  Recruiting Phase 3 Università Vita-Salute San Raffaele · Milan · NCT06503016

• Cardioneuroablation for treating bradycardia

  This study is testing a new procedure called cardioneuroablation to see if it can help people with slow heart rates feel better without needing a permanent pacemaker.

  Recruiting Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health · Saint Petersburg · NCT06288633

• Registry for cardioneuroablation in patients with recurrent vasovagal syncope

  This study is collecting information to see how well a new treatment called cardioneuroablation works for people with frequent fainting spells caused by vasovagal syncope.

  Recruiting at 11 sites University Hospital, Bordeaux · Bron and 13 other locations · NCT06159764

• Evaluating the Aveir Atrial Leadless Pacemaker for Medicare Patients

  This study is testing how well the Aveir Atrial Leadless Pacemaker works and what complications it might cause for Medicare patients compared to a regular pacemaker.

  Recruiting Abbott Medical Devices · Sylmar, California · NCT06100770

• Chronic Evaluation of a New Pacemaker System

  This study tests a new single‑chamber pacemaker called Calyan to see if it is safe and may work for adults with bradycardia who need ventricular pacing.

  Recruiting Calyan Technologies · Minneapolis, Minnesota · NCT06056817

• Evaluating the long-term safety of the Aveir DR leadless pacemaker

  This study is testing the long-term safety of the Aveir DR leadless pacemaker in real-world patients to make sure it’s safe for use.

  Recruiting Abbott Medical Devices · Sylmar, California · NCT05935007

• Comparing cardioneuroablation and permanent pacing for treating bradycardia symptoms.

  This study is testing if a new treatment called cardioneuroablation can help people with slow heart rates feel better and possibly stop using their pacemakers.

  Recruiting at 2 sites 4th Military Clinical Hospital with Polyclinic, Poland · Radom, Masovian Voivodeship and 1 other locations · NCT05896592

• Comparing two pacing methods for treating slow heart rates

  This study is testing two different ways to help people with slow heart rates feel better by comparing traditional pacing to a newer method in 2600 patients.

  Recruiting at 45 sites Imperial College London · Dublin and 44 other locations · NCT05815745

• New Algorithm for Cardiac Neuromodulation Therapy

  This study is testing a new way to set up a heart device to see if it can help people with slow heart rates and high blood pressure feel better.

  Recruiting at 3 sites BackBeat Medical Inc · Prague and 6 other locations · NCT05719454

• Using womb sounds to help preterm infants breathe better

  This study tests if playing womb sounds can help preterm infants breathe better by supporting their brain development during a crucial time.

  Recruiting Case Western Reserve University · Cleveland, Ohio · NCT05298748

• Assessing remote monitoring functions in pacemakers

  This study is testing how well remote monitoring features in certain pacemakers work to keep patients safe over four years after their surgery.

  Recruiting at 18 sites MicroPort CRM · Krems and 18 other locations · NCT05165095

• Monitoring sleep apnea using pacemakers

  This study is testing if data from pacemakers can help track sleep apnea and daily activity in people with slow heart rates, while also looking at how these factors relate to heart health over five years.

  Recruiting Medical University Innsbruck · Innsbruck, Tyrol · NCT05127720

• Monitoring heart rate changes during eye muscle surgery

  This study is testing how eye muscle surgery affects heart rate in patients to better understand their body's response during the procedure.

  Recruiting Alaska Blind Child Discovery · Anchorage, Alaska · NCT04353960

• Observing patients with BIOTRONIK Implantable Cardiac Monitors

  This study looks at how well the BIOMONITOR III and similar heart monitors work and keep patients safe over time.

  Recruiting at 23 sites Biotronik SE & Co. KG · Adelaide and 30 other locations · NCT04075084

• Registry for implantable cardiac devices

  This study is tracking how well pacemakers and defibrillators work for people with heart rhythm problems to see if they can improve patient care and outcomes.

  Recruiting Heinrich-Heine University, Duesseldorf · Düsseldorf · NCT03360227

• Evaluating His Bundle Pacing for Heart Conditions

  This study is testing if special pacing techniques during pacemaker implantation can help improve heart function in people with heart failure or slow heart rates.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT03008291

• Evaluating long-term performance of Medtronic cardiac devices

  This study is testing how well Medtronic heart devices, like pacemakers and defibrillators, work over the long term for people who have recently received or are about to receive one of these implants.

  Recruiting at 223 sites Medtronic · Birmingham, Alabama and 337 other locations · NCT00271180

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Improving chest compressions for newborns with low heart rates during resuscitation

  This study is looking at the best way to give chest compressions to newborns with slow heart rates during resuscitation, to help improve their chances of survival and protect their brains.

  NIH research State University of New York at Buffalo · Amherst, United States · NIH-11158673

Related topics

Quick answers

How many Bradycardia clinical trials are recruiting right now?

38, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 44 countries. The most sites are in United States (9 trials), France (8 trials), Czechia (7 trials), Germany (7 trials), Italy (7 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 3, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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