Pulse palpation vs arterial blood pressure in circulatory shock

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This international, multicenter, prospective observational study examines the relationship between palpable peripheral pulses (carotid, femoral, and radial) and concurrently measured arterial blood pressure in adults with circulatory shock or impending circulatory failure. Patients already under routine hemodynamic monitoring will have pulse palpation performed as part of standard care, while non-invasive or invasive blood pressure data are collected from their monitoring. The study aims to quantify how pulse presence or absence relates to systolic blood pressure, identify thresholds where pulses are palpable, compare invasive and non-invasive measurements, and explore how factors like vascular disease or vasoactive medications affect palpability. No changes to treatment will be made for the study, and data collection occurs during normal clinical care. Results could improve bedside assessment of circulation in emergency, critical care, and resuscitation settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical signs of circulatory shock or impending circulatory failure
* Availability of non-invasive and/or invasive arterial blood pressure monitoring
* Pulse palpation possible without interfering with emergency care

Exclusion Criteria:

* Peripheral vascular conditions preventing reliable pulse palpation
* Major extremity amputation affecting assessment sites
* Clinical situations where study procedures interfere with life-saving treatment

Where it's running

• Region Stockholm, all hospitals
  Stockholm, Stockholm County, Sweden Recruiting

Study contacts

• Study coordinator: Mattias Günther, MD PhD
• Email: mattias.gunther@ki.se
• Phone: 46812361000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.