Pupil light reflex to predict low blood pressure after spinal anesthesia in cesarean deliveries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational study will measure pre-anesthetic pupillary light reflex (PLR) parameters, such as reaction latency, baseline pupil size, constriction velocity, and minimum diameter, using a handheld pupillometer after dark adaptation. Researchers will then monitor maternal blood pressure every 5 minutes for the first 20 minutes after spinal anesthesia with hyperbaric bupivacaine and fentanyl, defining hypotension as a greater than 20% drop in systolic pressure. The goal is to determine whether PLR metrics can predict the occurrence and severity of post-spinal hypotension in elective cesarean patients and improve risk stratification beyond current predictors like baseline BP and BMI.

Why it matters

Who can join: the full rules

Inclusion Criteria:

ASA II Term pregnancy ≥37 weeks Singleton pregnancy Elective cesarean section Age 18-45 years Written informed consent

Exclusion Criteria:

Emergency cesarean section Hypertensive disorders Diabetes mellitus Cardiovascular disease Neurological or autonomic disorders Ophthalmic disease Medications affecting autonomic function BMI \>40 kg/m² Failed spinal anesthesia

Where it's running

• Al-Azhar University Hospitals
  Damietta, Egypt Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.