Compare two norepinephrine doses to prevent low blood pressure after spinal anesthesia for C-section

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center interventional study compares two prophylactic norepinephrine infusion rates given around the time of spinal anesthesia for planned cesarean delivery. Eligible term pregnant women without major cardiac disease, hypertensive disorders, severe obesity, or contraindications to spinal anesthesia will receive one of the two norepinephrine regimens during the operation. Maternal blood pressure, need for rescue vasopressors, and common side effects such as nausea, bradycardia, or hypertension will be recorded and compared between groups. The goal is to identify which infusion rate better prevents post-spinal hypotension with acceptable safety.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pregnant women scheduled for cesarean section under spinal anesthesia
* Gestational age of at least 37 weeks

Exclusion Criteria:

* Patient refusal
* Contraindications of spinal anesthesia
* Allergy to the study drug
* Height\<150 cm, weight \< 60 kg, body mass index (BMI) ≥40 kg/m2.
* patients with cardiac morbidities
* Hypertensive disorders of pregnancy.
* Prepartum hemorrhage

Where it's running

• Assiut University Woman Health Hospital
  Asyut, Egypt Recruiting

Study contacts

• Study coordinator: Zakaria A. Zakaria
• Email: za6841924@gmail.com
• Phone: +201150637566

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Predicting low blood pressure from spinal anesthesia during cesarean section

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• Mindfulness-based breathing before spinal anesthesia for elective cesarean delivery

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• Cardiac Arrest: Using Ultrasound to Find Hidden Blood Flow

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  Recruiting University of Massachusetts, Worcester · Denver, Colorado and 7 other locations · NCT07897370

• Effects of massage and exercises on cesarean scar and recovery

  This study tests whether direct scar massage or indirect massage plus exercise helps people recover after a cesarean birth and reduces scar-related pain.

  Recruiting Concordia University, Montreal · Montreal, Quebec · NCT07897253

• Reflexology and hand massage after cesarean section

  This study tests whether reflexology hand massage or stroking hand massage can reduce anxiety and increase satisfaction, and how they affect heart/blood pressure after cesarean delivery.

  Recruiting Dokuz Eylul University · Izmir · NCT07880587

• Health education to see if primigravida women choose vaginal delivery more often

  A health education program is being tested to see if it helps first-time pregnant women in choosing vaginal delivery over unnecessary cesareans.

  Recruiting Assiut University · Asyut, Asyut Governorate · NCT07810751

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.