Condition

Hemodynamic Instability clinical trials and research

• 20Clinical trials
• 1NIH research projects
• 11Countries

Newest Hemodynamic Instability clinical trials

All recruiting trials (20)

• Preoperative NPAR and Post-Induction Hemodynamic Vulnerability in Major Oncologic Surgery

  This study checks if the preoperative neutrophil percentage-to-albumin ratio (NPAR) can flag who might become hemodynamically unstable after anesthesia induction in adults having major cancer surgery.

  Recruiting Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · Ankara, Yeni̇mahalle · NCT07804706

• Pulse palpation vs arterial blood pressure in circulatory shock

  This study tests how well feeling for a pulse at typical sites matches the actual arterial blood pressure in adults with circulatory shock or risk of failure.

  Recruiting Region Stockholm · Stockholm, Stockholm County · NCT07609095

• Mindfulness-based breathing before spinal anesthesia for elective cesarean delivery

  This trial will test whether a 5-minute mindfulness slow-breathing exercise just before spinal anesthesia can reduce blood pressure drops and anxiety in pregnant women having elective cesarean delivery.

  Recruiting Ataturk University · Erzurum · NCT07494955

• Electrical stimulation plus isometric exercise to improve blood flow in resistant high blood pressure

  This will try whether adding upper‑thoracic electrical stimulation (TENS) and isometric exercise to usual blood pressure medications can lower blood pressure and improve peripheral blood flow in men and women aged 50–60 with resistant hypertension.

  Recruiting Cairo University · Port Said, Port Said Governorate · NCT07383220

• Predicting fluid responsiveness using PLR, PPV, and LVOT VTI in ICU patients

  In critically ill adults on ventilators, researchers test whether measuring LVOT VTI during a passive leg raise can help predict who will respond to fluid therapy.

  Recruiting Izmir Katip Celebi University · Izmir · NCT07304661

• Non-invasive continuous blood pressure monitoring during intracranial aneurysm coil embolization

  This trial tests whether the ClearSight non‑invasive continuous blood pressure monitor can safely replace radial arterial catheter monitoring for adults having coil embolization of unruptured intracranial aneurysms.

  Recruiting Korea University Anam Hospital · Seoul · NCT07246148

• HemoSphere Alta advanced hemodynamic and cerebral monitoring during transplant and cardiac surgery

  This project will test the HemoSphere Alta monitoring platform with a pulmonary artery catheter plus brain and hemodynamic sensors in adults having cardiac or liver transplant surgery who need advanced intraoperative monitoring.

  Recruiting Becton, Dickinson and Company · Rochester, New York · NCT07148323

• Oxygen use and carbon dioxide production after stabilizing blood flow in shock

  This project will see if giving fluids or norepinephrine to adults in the ICU with shock changes how much oxygen their bodies use and how much carbon dioxide they make, measured from the ventilator and compared with blood gas calculations.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma · NCT07107724

• AI-guided blood-pressure and fluid management during cytoreductive surgery with HIPEC

  This trial will test whether an AI-based hemodynamic monitoring protocol during cytoreductive surgery with HIPEC helps adults with ovarian cancer avoid low blood pressure and fluid overload.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome · NCT07070973

• Urine Output Monitoring to Guide Fluid and Diuretic Therapy in Cardiac ICU Patients

  This observational study tests how continuous urine output data from the FIZE kUO device can help guide fluid therapy and diuretic use in adults after heart surgery.

  Recruiting FIZE Medical ltd · Petah Tikva · NCT07022314

• Evaluating AI in Analyzing Arterial Waveform Data

  This study tests whether AI models can accurately analyze heart data from patients having surgery to help doctors make better treatment decisions.

  Recruiting Kanuni Sultan Suleyman Training and Research Hospital · Istanbul · NCT06828575

• Observing the effects of Pipeline embolization on intracranial aneurysms

  This study looks at how well the Pipeline device works and its safety for people with brain aneurysms who have had it implanted.

  Recruiting Zhujiang Hospital · Guangzhou, Guangdong · NCT06446778

• Monitoring blood flow during surgery for craniosynostosis

  This study is testing new ways to monitor blood flow during surgery for craniosynostosis in infants to see if they can make the procedure safer and more effective.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, BO · NCT06263075

• Understanding how different anesthetics affect brain blood flow and oxygen levels during MRI

  This study is testing how different types of anesthesia affect blood flow and oxygen levels in the brain during MRI scans in kids and teens.

  Recruiting Children's Hospital Los Angeles · Los Angeles, California · NCT06195345

• Improving heart assessment in fetuses and newborns

  This study is testing new ways to check the heart health of unborn babies and newborns to help prevent serious problems during delivery.

  Recruiting Oslo University Hospital · Oslo · NCT06186973

• Measuring blood flow and circulation in ICU patients with septic shock

  This study is testing how the medication norepinephrine affects blood flow in adults with septic shock to help doctors provide better treatment.

  Recruiting Copenhagen University Hospital, Hvidovre · Hvidovre, Copenhagen · NCT05225402

• Using carotid doppler peak velocity to predict fluid responsiveness during major abdominal surgery

  This study is testing if measuring changes in blood flow in the carotid artery can help doctors decide how much fluid patients with septic shock need during major abdominal surgery.

  Recruiting Johannes Gutenberg University Mainz · Mainz, Rhineland-Palatinate · NCT05185141

• Evaluating the use of transesophageal echocardiography in critically-ill patients

  This study tests how using a special heart ultrasound called transesophageal echocardiography can help critically-ill patients in emergency and intensive care settings.

  Recruiting University of Pennsylvania · Chicago, Illinois · NCT04972526

• Monitoring blood flow changes during controlled low blood volume conditions

  This study is testing how lowering blood volume affects blood flow in healthy people to find the best ways to monitor these changes.

  Recruiting Yale University · New Haven, Connecticut · NCT03592290

• Optimizing oxygen consumption during major abdominal surgery

  This study tests a new way to manage fluid levels during major abdominal surgery to see if it helps patients recover better compared to the usual care.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma · NCT03113435

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• How bicarbonate levels in dialysis affect heart stability and rhythm

  This study is looking at how the amount of bicarbonate in the dialysis fluid affects blood pressure and heart health for people on hemodialysis, with the goal of finding the best levels to help keep patients safe and healthy during their treatments.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10829336

Related topics

Quick answers

How many Hemodynamic Instability clinical trials are recruiting right now?

20, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in Italy (4 trials), United States (4 trials), Turkey (Türkiye) (4 trials), South Korea (1 trial), Sweden (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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