How blood vessel properties affect anesthesia-related low blood pressure in very young and older patients
Vascular Determinants of Anesthesia-Induced Hypotension at the Extremes of Age
This study is looking into why babies and older adults often have low blood pressure when they are put under anesthesia, so we can find better ways to keep them safe during surgery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10898716 on NIH RePORTER |
What this research studies
This research investigates the reasons why very young patients (like infants) and older adults are more likely to experience low blood pressure during anesthesia. By using both laboratory and animal studies, the researchers aim to uncover the unique characteristics of blood vessels in these age groups that contribute to this problem. Understanding these mechanisms could help improve anesthesia safety and outcomes for vulnerable populations. The findings could lead to better strategies for managing blood pressure during surgeries.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants, children, and older adults who are scheduled for surgeries requiring general anesthesia.
Not a fit: Patients who are not undergoing surgery or those outside the age extremes (neonates and older adults) may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved anesthesia techniques that reduce the risk of low blood pressure in very young and older patients during surgery.
How similar studies have performed: Previous research has indicated that understanding vascular responses in different age groups can lead to improved anesthesia practices, suggesting potential success for this approach.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Whitaker, Emmett E — Johns Hopkins University
- Study coordinator: Whitaker, Emmett E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.