Condition

Colorectal Cancer Screening clinical trials and research

• 16Clinical trials
• 47NIH research projects
• 6Countries

Newest Colorectal Cancer Screening clinical trials

All recruiting trials (16)

• Electrolyte beverage plus PEG for colonoscopy bowel prep

  This randomized trial tests different mixes of electrolyte drink and water with PEG to see which bowel prep regimen gives the best cleansing for adults getting colonoscopy.

  Recruiting Nanfang Hospital, Southern Medical University · Guangzhou, Guangdong · NCT07608120

• Using prior CT scans to guide colonoscope insertion

  This trial will test whether using a patient's existing abdominal/pelvic CT scan to guide colonoscope insertion makes colonoscopy faster and more comfortable for adults having screening or diagnostic colonoscopy.

  Recruiting Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT07541924

• Animated storytelling video to boost colorectal cancer screening

  A short animated video is being tested to see if it makes adults in the U.S. who haven’t been screened more likely to plan getting screened for colorectal cancer.

  Recruiting Stanford University · Stanford, California · NCT07522177

• Does GP endorsement and early information improve colonoscopy follow-up after a positive colorectal cancer screening test?

  This study tests whether giving patients early information about colonoscopy and having their GP endorse the follow-up can increase how many people in France get a colonoscopy within six months after a positive screening result.

  Recruiting Phase 3 University Hospital, Caen · Tours, France · NCT07520578

• Pilot of a colorectal cancer education program

  This program will test whether a culturally and language‑targeted education program helps adults aged 45–75 who are overdue for colorectal cancer screening complete recommended screening.

  Recruiting NYU Langone Health · New York, New York · NCT07361614

• Noninvasive blood miRNA test to screen for multiple gastrointestinal cancers.

  This project will test whether a blood-based microRNA panel can detect several types of gastrointestinal cancer in adults using stored blood samples.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07224750

• Cleansing options to improve colonoscopy tolerance

  This test compares low-volume tablet bowel preps (Sutab/Suflave) with standard Golytely for adults having outpatient colonoscopies to see which is better tolerated and preferred.

  Recruiting Phase 4 Morehouse School of Medicine · Atlanta, Georgia · NCT07215000

• Testing a new stool test for colorectal cancer detection

  This study is testing a new stool test to see if it can help find colorectal cancer and advanced growths in people aged 45 and older who are at average risk.

  Recruiting Mainz Biomed · Morrisville, North Carolina · NCT06864338

• Lifestyle advice for people with adenomas after a positive colorectal screening test

  This trial will try giving evidence-based diet and lifestyle advice to people in France who had a positive FIT and adenomas but no cancer to see if it improves their diet, activity, quality of life, and body measurements over one year.

  Recruiting Centre Leon Berard · Lyon, France · NCT06827366

• Closing the gap between a positive FIT test and diagnostic colonoscopy

  This project will test patient- and system-level strategies to increase follow-up colonoscopy after a positive FIT for patients aged 45–75 at a Boston community health center.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT06763432

• Colorectal cancer screening for unscreened people aged 45–54

  This project will try to find what helps or gets in the way of colorectal cancer screening for patients aged 45–54 at community health centers by talking with patients and staff and linking staff survey results to clinic records.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT06757192

• Education and screening for colorectal cancer and hepatitis C

  This study is trying to see if educating patients aged 45-75 about colorectal cancer and hepatitis C can help them get screened for these conditions more often.

  Recruiting H. Lee Moffitt Cancer Center and Research Institute · Tampa, Florida · NCT06745895

• Identifying gut microbiome biomarkers for early colorectal cancer screening in Portugal

  This study is trying to find specific gut bacteria in stool samples from people aged 40-74 in Lisbon to see if they can help detect early signs of colorectal cancer more accurately.

  Recruiting Gulbenkian Institute for Molecular Medicine · Lisbon, Lisbon District · NCT06741293

• Collecting blood samples to develop a colorectal cancer screening test

  This study is collecting blood samples from people at average risk for colorectal cancer to see if they can create a new blood test for early detection of the disease.

  Recruiting Natera, Inc. · Austin, Texas · NCT06620627

• Total underwater colonoscopy for better colorectal cancer screening

  This study is testing if total underwater colonoscopy can find more hard-to-detect lesions during colorectal cancer screening in people who need a colonoscopy after a positive stool test.

  Recruiting at 5 sites Vestre Viken Hospital Trust · Drammen and 4 other locations · NCT06333392

• Training doctors to improve patient decision-making in colorectal cancer screening

  This study tests whether training doctors to communicate better with patients can help more people get screened for colorectal cancer.

  Recruiting CNGE Conseil · Soisy-sous-Montmorency · NCT06074536

NIH-funded research (newest 40 of 47)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Improving colorectal cancer screening and follow-up care.

  This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.

  NIH research Research Triangle Institute · Research Triangle Park, United States · NIH-9627071

• Making colorectal cancer screening easier and more likely to happen

  This project uses default options, simpler choices, and direct outreach to help average-risk adults who are overdue complete colorectal cancer screening with colonoscopy or stool tests.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11473206

• AI/AN Tailoring of a Home-Based Cervical and Colorectal Cancer Screening Program

  A tailored, home-based cancer screening program helps AI/AN adults screen for cervical and colorectal cancer from home using self-collection tests and culturally aligned education.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11443461

• Bringing colorectal cancer screening to adults 45–54 who haven’t been screened

  A grant to help low-income adults aged 45–54 start colorectal cancer screening through the Boston area’s community health centers.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11399873

• Increasing follow-up colonoscopies after a positive FIT in community clinics

  Aims to help people with abnormal stool tests for colorectal cancer get timely follow-up colonoscopies in safety-net clinics.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11399152

• Colorectal cancer screening with real-time imaging that may replace sedated scopes

  Researchers are testing a new imaging method called optical coherence tomography (OCT) to spot and treat colon polyps without the need for sedation during a screening colonoscopy.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11387602

• Promoting follow-up after abnormal colorectal cancer screening in safety-net systems

  A multilevel program will help people in safety-net hospitals complete follow-up colonoscopy after an abnormal stool test.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11381170

• Bundled home self-collection for cervical and colorectal cancer screening

  This study tests whether sending at-home self-collection kits for both cervical and colorectal cancer screening together increases screening for women who are overdue.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11344260

• Understanding colorectal cancer screening gaps among Veterans to improve outcomes

  This project looks at why Veterans aren’t getting recommended colorectal cancer screening and how to fix barriers to improve health outcomes.

  NIH research Veterans Admin Palo Alto Health Care Sys · Palo Alto, United States · NIH-11343579

• Helping childhood cancer survivors and their primary care doctors increase colorectal cancer screening

  A remote digital program will help childhood cancer survivors aged 30 and older and their primary care doctors get recommended colorectal cancer screening.

  NIH research Lurie Children's Hospital of Chicago · Chicago, United States · NIH-11326096

• Helping patients in primary care complete colorectal cancer screening, especially Spanish speakers

  This project offers a brief decision tool and clinic support to help adults, especially those who prefer Spanish, complete colorectal cancer screening.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11322124

• Bringing colorectal cancer screening to rural clinics

  This project tests whether mailing FIT kits plus offering patient navigation helps more people in rural communities complete colorectal cancer screening.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11294213

• Tracking community programs to increase colorectal cancer screening among African Americans

  This project reconnects with African American adults to help more people complete at-home stool tests and get needed follow-up care for colorectal cancer screening.

  NIH research Florida Agricultural and Mechanical Univ · Tallahassee, United States · NIH-11290721

• Colon cancer screening based on your life expectancy

  This project tries a new way to help doctors and patients decide whether adults over 75 should get colon cancer screening by using estimated life expectancy.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11252600

• Best way to start colon cancer screening earlier

  Finding better ways to encourage colon cancer screening for adults aged 45–49 so cancers can be found earlier.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11251956

• Colorectal cancer screening at community pharmacies

  This project offers at-home stool tests (FIT) through neighborhood pharmacies to help adults 21 and older get screened for colorectal cancer.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11251595

• Making colorectal cancer screening easier and more automatic

  This project compares two ways of inviting adults overdue for colorectal cancer screening—using doctor prompts and outreach—to help more people complete screening.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11235900

• Improving colorectal cancer screening using behavioral economics

  This study is looking to improve how many people get screened for colorectal cancer by using friendly reminders from doctors and reaching out directly to patients, and it will compare two options for screening: getting a colonoscopy right away or starting with a simpler test first, for those who might want to wait.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11212487

• Increasing colonoscopy follow‑up after a positive stool colorectal screening at community health clinics

  This project tests clinic‑level and patient supports to help people at community health centers get timely colonoscopies after a positive stool-based colorectal cancer screening.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11184329

• A digital health guide for colorectal cancer screening

  This project is creating an easy-to-use online tool to help more people get screened for colorectal cancer.

  NIH research Digital Health Navigation Solutions, LLC · Winston Salem, United States · NIH-11146650

• Optical coherence tomography for improved colon polyp detection and treatment

  This work is developing a tiny imaging tool that can see behind colon folds to help doctors spot, diagnose, and potentially treat polyps in real time without routine sedation.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11142667

• A digital health program to improve colorectal cancer screening

  This study is testing a new online program called mPATH™ that helps people understand the importance of getting screened for colorectal cancer and makes it easier for them to request their screening tests, all to encourage more folks to get screened.

  NIH research Digital Health Navigation Solutions, LLC · Winston Salem, United States · NIH-11116005

• Improving colorectal cancer screening in primary care for Spanish-speaking communities

  This study is looking to improve colorectal cancer screening for Spanish-speaking patients by testing a new decision-making tool in clinics, comparing two different ways to introduce it, so we can find the best way to help more people get screened.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11087614

• Improving colorectal cancer screening in underserved communities in Brooklyn

  This study is working to help more people in Brooklyn get screened for colorectal cancer by reaching out to those who might not usually go to the doctor, especially by sending them invitations and offering support to make the process easier.

  NIH research New York University School of Medicine · New York, United States · NIH-11077751

• Improving colorectal cancer screening using a digital toolkit

  This study is testing a helpful digital tool called the eNav Toolkit to make it easier for people at community health centers to get screened for colorectal cancer by providing reminders and information right on their phones or computers.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11051184

• Increasing colorectal cancer screening in African Americans

  This study is helping African Americans aged 45-64 in north Florida get better access to colorectal cancer screenings by providing support and education through a friendly 6-week program, so they feel motivated to complete their tests.

  NIH research Florida Agricultural and Mechanical Univ · Tallahassee, United States · NIH-11047657

• Improving decisions for colorectal cancer screening based on life expectancy

  This study is looking to help doctors make better decisions about colorectal cancer screening for older adults aged 76 to 85 by taking into account how long they might live, so that patients can get the right care based on their health and needs.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11047229

• Helping childhood cancer survivors and their doctors improve colorectal cancer screening

  This study is looking to help childhood cancer survivors who had radiation treatment in their belly or pelvis and are at a higher risk for colorectal cancer by using a digital program to encourage them and their doctors to follow screening guidelines better.

  NIH research University of Chicago · Chicago, United States · NIH-11030321

• Improving access to colorectal cancer screening through pharmacies

  This study is looking at how we can make it easier for people in underserved communities to get screened for colorectal cancer by offering simple tests at local pharmacies, so they don’t have to go to a doctor’s office, and then helping those who test positive get the follow-up care they need.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11018612

• Improving colorectal cancer screening in rural clinics

  This study is looking for ways to help more people in rural areas get screened for colorectal cancer by sending them easy-to-use home tests and providing support to help them follow up with necessary doctor visits.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11011364

• Improving colorectal cancer screening using behavioral economics

  This study is looking to help more people get screened for colorectal cancer by trying out different ways to encourage both doctors and patients, and it will involve about 20,000 patients who are due for screening at 30 different primary care clinics.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11000832

• Increasing colorectal cancer screening for people aged 45 to 54

  This study is working to help more people aged 45 to 54, especially in the Black community, get screened for colorectal cancer by finding better ways to raise awareness and make screening easier at Codman Square Health Center in Boston.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-10985080

• Improving colorectal cancer screening using advanced imaging technology

  This study is testing a new imaging technology called optical coherence tomography (OCT) to make colorectal cancer screenings better by helping doctors see hard-to-reach areas in the colon, which could lead to more accurate polyp detection and a more comfortable, less invasive experience for patients.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-10979884

• Finding the best age to start screening for colorectal cancer

  This study is looking at the best age for people between 45 and 49 to start getting screened for colorectal cancer, and it wants to find out how comfortable they feel about it and what might encourage them to participate, while also making sure everyone, no matter their background, has a fair chance to get screened.

  NIH research University of California, San Diego · La Jolla, United States · NIH-10949013

• Improving follow-up colonoscopy after abnormal stool tests for colorectal cancer

  This study is looking for better ways to help patients with abnormal stool test results get the colonoscopies they need, especially in community health centers, so we can catch and prevent colorectal cancer early.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-10940536

• Improving colorectal cancer screening for underserved populations

  This study is all about helping Black individuals get screened for colorectal cancer more often, as they are at higher risk, by providing support and guidance through the healthcare system to make the process easier and more accessible.

  NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-10933504

• Improving colorectal cancer screening for Alaska Native people using a new stool DNA test

  This study is looking at a new at-home stool DNA test for colorectal cancer to see if it can help more people in Alaska Native communities get screened and reduce cancer deaths, all while working closely with local health organizations to make sure it fits their needs.

  NIH research Alaska Native Tribal Health Consortium · Anchorage, United States · NIH-10918041

• Improving colorectal cancer screening for diabetes patients in community health centers

  This study is looking at how to make colorectal cancer screening easier and more effective for people with diabetes, especially those in low-income communities, so everyone can get the preventive care they need, no matter their background.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-10904675

• Improving colorectal cancer screening for Chinese American immigrants

  This study is creating a friendly program called CLEAN to help Chinese American immigrants understand and get screened for colorectal cancer, making it easier for them to take part in this important health check.

  NIH research New York University School of Medicine · New York, United States · NIH-10903748

• An online tool to help people decide on colorectal cancer screening options

  This study is testing a helpful online tool called ACCESS that aims to make it easier for people to understand their options for colorectal cancer screening, so they can make informed choices and talk more effectively with their doctors about getting screened.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-10839837

Related topics

Quick answers

How many Colorectal Cancer Screening clinical trials are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (9 trials), France (3 trials), China (2 trials), Portugal (1 trial), Norway (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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