Clinical trial Recruiting at 1 site Interventional Ages 45 to 75

Education and screening for colorectal cancer and hepatitis C

Official title: Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening (MATCHES)

Run by H. Lee Moffitt Cancer Center and Research Institute · NCT06745895 · Data updated 2026-11-12

This study is trying to see if educating patients aged 45-75 about colorectal cancer and hepatitis C can help them get screened for these conditions more often.

More Colorectal Cancer Screening trials

Quick facts

Study typeInterventional
Ages45 Years to 75 Years
SexAll
Enrollment350 (estimated)
SponsorH. Lee Moffitt Cancer Center and Research Institute
Academic / other
Locations1 site (Tampa, Florida)
StatusRecruiting
StartedOctober 21, 2024
Main results expectedOctober 2027
Study endsApril 30, 2028
Registry record updatedSeptember 16, 2026
Trial IDNCT06745895 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients aged 45-75 receiving care at participating FQHC clinics who are not up to date with CRC screening and have never been screened for HCV.

Probably not a fit

Patients with a personal history of colorectal cancer or current symptoms suggestive of CRC will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This intervention promotes concurrent screening for colorectal cancer (CRC) and hepatitis C virus (HCV) among patients aged 45-75 at Federally Qualified Health Centers (FQHCs). The MATCHES program focuses on educating patients about the importance of screening and ensuring they receive the necessary tests. The study aims to improve screening rates by targeting individuals who are not up to date with CRC screening and have never been screened for HCV. The intervention includes providing educational materials and support to facilitate participation in screening.

Why it matters

Potential benefit: If successful, this initiative could significantly increase screening rates for colorectal cancer and hepatitis C, leading to earlier detection and improved patient outcomes.

How similar studies have gone: Other studies have shown success in increasing screening rates through educational interventions, making this approach promising but not entirely novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants must be receiving care at one of the participating FQHC clinics.
* Participants must be 45-75 years of age.
* Participants must not be up to date with Colorectal Cancer (CRC) screening recommendations such as no colonoscopy in the past 10 years, occult blood test in the past 12 months.
* Participants must never have had Hepatitis C Virus (HCV) antibody screening.
* Participants must be able to read, write, and understand English or Spanish.
* Participants must have no personal history of CRC or current presumptive CRC symptoms such as unresolved rectal bleeding or abdominal pain/bloating.
* Participants must be at average risk for CRC (no hereditary CRC syndromes such as lower gastrointestinal (GI) bleeding, persistent diarrhea, bloating, or lower GI pain, no strong family history of CRC).
* Participants must be asymptomatic for HCV.
* Participants receiving intervention materials must be able and willing to complete surveys and receive the patient level intervention.
* Participants completing qualitative interviews must be willing to complete a remote interview via phone or teleconference software such as ZOOM.
* Participants completing qualitative interviews must be willing to be audio recorded.
* Participants recruited for qualitative interviews only (did not receive MATCHES intervention materials) must have a clinic visit within prior two months.
* All Participants must be able to provide informed consent.

Exclusion Criteria:

* Participants that do not meet all Inclusion Eligibility requirements will be excluded.

Where it's running

  • Moffitt Cancer Center
    Tampa, Florida, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.