Electrolyte beverage plus PEG for colonoscopy bowel prep
Official title: Randomized Controlled Trial of Different Ratios of Electrolyte Beverage and Water Combined With Polyethylene Glycol on Bowel Preparation Quality and Ingestion Rhythm Before Colonoscopy
Run by Nanfang Hospital, Southern Medical University · NCT07608120 · Data updated 2026-11-12
This randomized trial tests different mixes of electrolyte drink and water with PEG to see which bowel prep regimen gives the best cleansing for adults getting colonoscopy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 405 (estimated) |
| Sponsor | Nanfang Hospital, Southern Medical University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Status | Recruiting |
| Started | May 18, 2026 |
| Main results expected | January 31, 2027 |
| Study ends | May 31, 2027 |
| Registry record updated | May 27, 2026 |
| Trial ID | NCT07608120 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18-75 scheduled for elective colonoscopy who can comply with PEG intake and study procedures.
✕Probably not a fit
Patients with known PEG allergy, significant kidney or heart conditions, or other exclusions may not benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults aged 18-75 undergoing elective colonoscopy are randomly assigned to three bowel prep regimens: PEG with water only, PEG with a low-dose electrolyte beverage, and PEG with a medium-dose electrolyte beverage. The study will measure bowel cleansing quality with the Boston Bowel Preparation Scale, as well as tolerability, adverse events, completion rate, need for repeat colonoscopy, and adenoma detection rate. It also explores whether electrolyte beverage use affects ingestion rhythm and adherence during PEG intake. The trial is conducted at Nanfang Hospital, Southern Medical University, with the lead sponsor coordinating the study.
Why it matters
Potential benefit: If successful, electrolyte beverage-assisted regimens could improve bowel cleansing quality and patient experience before colonoscopy.
How similar studies have gone: Previous work in bowel preparation has explored electrolyte-containing regimens, with mixed results; this study adds a controlled comparison of two electrolyte-dose levels.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18-75 years scheduled to undergo elective colonoscopy * Meet the standard clinical indications for colonoscopy; * Able to understand and comply with the bowel preparation procedure and complete oral polyethylene glycol (PEG) intake as required; * Able to comply with study-related data collection and follow-up; * Provide written informed consent voluntarily. Exclusion Criteria: * Previously diagnosed colorectal cancer, intestinal obstruction, or suspected intestinal obstruction; * Active gastrointestinal bleeding or a definite history of gastrointestinal bleeding within the past 4 weeks (including melena, hematochezia, or hematemesis); * Severe renal insufficiency, decompensated heart failure, significant electrolyte imbalance, or other conditions unsuitable for PEG bowel preparation; * Known allergy to polyethylene glycol or components of the electrolyte beverage used in the study; * Pregnant or breastfeeding women; * Any other condition considered by the investigators to make the participant unsuitable for the study.
Where it's running
-
Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China Recruiting
Study contacts
- Study coordinator: Aimin Li
- Email: lam0725@163.com
- Phone: +86 13580317630
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.