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Gastric Cancer (GC) clinical trials and research

• 30Clinical trials
• 1New in 30 days
• 11Countries

Newest Gastric Cancer (GC) clinical trials

All recruiting trials (30)

• TEAS after gastrectomy to aid recovery after laparoscopic stomach cancer surgery

  A randomized trial tests whether transcutaneous electrical acupoint stimulation (TEAS) after laparoscopic gastrectomy helps people recover faster and with less pain compared with a sham treatment.

  Recruiting at 8 sites The Affiliated Hospital of Qingdao University · Qingdao, Shandong and 7 other locations · NCT07898293

• Anti-PD-1 with chemotherapy and intraperitoneal nab-paclitaxel for untreated advanced gastric cancer with ascites

  This study tests whether adding anti-PD-1 therapy to standard chemotherapy plus intraperitoneal nab-paclitaxel can help patients with untreated advanced gastric cancer and malignant ascites.

  Recruiting Zhejiang Cancer Hospital · Hangzhou, Zhejiang · NCT07855640

• Intratumoral oncolytic virus plus immune checkpoint inhibitors in metastatic colorectal, gastric, or liver cancer

  Doctors are testing whether injecting an oncolytic virus directly into tumors along with immune checkpoint drugs is safe and may help people with advanced colorectal, gastric, or liver cancer who have tried many treatments.

  Recruiting Foshan Fosun Chancheng Hospital · Guangdong, Foshan · NCT07850882

• Multimodal Prehabilitation for Gastric Cancer Patients

  This program tests whether a combined pre- and post-operative wellness plan can reduce inflammation after gastric cancer surgery in adults.

  Recruiting National University Hospital, Singapore · Singapore · NCT07839702

• MGC030 in adults with advanced solid tumors

  This trial tests MGC030 in adults with advanced urothelial, gastric/GEJ, esophageal, colorectal, gastric, pancreatic, or GEJ cancers to see if it is safe and whether it can shrink tumors or stop growth.

  Recruiting Phase 1 MacroGenics · Lake Success, New York · NCT07822399

• TS-104: a first-in-human, dose-escalation study for advanced solid tumors

  This study tests TS-104, a peptide-drug conjugate, as a single therapy in adults with advanced solid tumors like NSCLC, HNSCC, esophageal, gastric, ovarian, or endometrial cancer to see if it is safe and tolerable and whether it shows any benefit.

  Recruiting at 3 sites Phase 1 TwoStep Therapeutics, Inc. · Maumee, Ohio and 2 other locations · NCT07814248

• Targeted alpha-radiation therapy for NTSR1-positive tumors using SKL35501/SKL35502

  This early-phase trial tests whether a two-part approach—an imaging agent to find NTSR1-expressing tumors and a targeted alpha-ray therapy—can be safely used in adults with certain advanced solid tumors.

  Recruiting Phase 1 SK Life Science, Inc. · Glen Burnie, Maryland and 4 other locations · NCT07812805

• Medical AI fine-tuning platform for major diseases

  This study tests a smart AI system that uses hospital data to help diagnose and guide care for patients with chronic gastritis, gastric cancer, reflux, coronary artery disease, or stroke.

  Recruiting Beijing Friendship Hospital · Beijing · NCT07795645

• Prevalence and possible role of non-H. pylori Helicobacter species in gastric conditions and cancers

  Researchers will test stomach tissue from people with functional dyspeasia, various gastritis conditions, gastric cancer, and bariatric patients to see if non-H. pylori Helicobacter species are present.

  Recruiting at 3 sites Universiteit Antwerpen · Edegem and 2 other locations · NCT07770126

• Concurrent Immunotherapy and SBRT for Stage IV Cancers

  This trial tests whether giving stereotactic body radiation therapy (SBRT) alongside approved immunotherapies can safely help control advanced cancers that have spread, while patients continue their planned treatments.

  Recruiting Phase 2 University of Kentucky · Lexington, Kentucky · NCT07770100

• TEAS timing to aid recovery after stomach cancer surgery

  This trial tests whether transcutaneous electrical acupoint stimulation (TEAS) given around surgery helps people recover faster after laparoscopic gastrectomy for gastric cancer.

  Recruiting The Affiliated Hospital of Qingdao University · Dongying, Shandong and 12 other locations · NCT07714980

• [68Ga]BED003 PET imaging to see fibroblast activity in selected cancers

  This study tests a PET imaging agent, [68Ga]BED003, to see how well it detects tumors in colorectal, gastric, pancreatic, ovarian, and invasive lobular breast cancers.

  Recruiting at 5 sites Phase 2 Blue Earth Diagnostics · Bergamo, Lombardy and 5 other locations · NCT07702292

• Chemoradiotherapy with CAPOX and SHR-1701 for unresectable gastric or GEJ cancer

  This study tests whether adding SHR-1701 to radiotherapy and CAPOX helps patients with unresectable locally advanced or metastatic gastric or gastroesophageal junction cancer see if they harm or help, with the goal of delaying progression and enabling possible surgery.

  Recruiting at 3 sites Phase 2 Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Shenzhen, Guangdong and 2 other locations · NCT07689851

• THE-0504 in patients with solid tumors

  A first-in-human, dose-escalation study to see if THE-0504 is safe and tolerable in adults with solid tumors such as SCLC, CRC, GC, TNBC, and pancreatic cancer.

  Recruiting Phase 1 Thena Biotech S.r.l. · Rome, Lazio · NCT07646106

• Double-tract vs tubular gastric reconstruction after proximal gastric cancer surgery

  This study compares two stomach-sparing surgeries after proximal gastric cancer to see how patients fare afterward.

  Recruiting Qilu Hospital of Shandong University · Jinan, Shandong · NCT07635836

• Personalized mRNA tumor vaccine plus standard therapy for high-risk recurrent solid tumors

  This early-phase study tests XH001, a personalized mRNA neoantigen vaccine, with standard adjuvant treatment in people with high-risk recurrent solid cancers after surgery to see if it’s safe and may help delay relapse.

  Recruiting at 2 sites Phase 1 Shenzhen Xinhe Biomedical · Beijing and 1 other locations · NCT07594964

• Immediate and functional outcomes after different reconstructions following proximal stomach removal

  This project will compare different ways of reconnecting the digestive tract after proximal gastrectomy to see which approach leads to better function and quality of life for people having surgery for cancers at the top of the stomach or the esophagogastric junction.

  Recruiting P. Herzen Moscow Oncology Research Institute · Moscow · NCT07441785

• AI-based prediction of who will respond to pre-surgery immunotherapy in locally advanced gastric cancer

  A real-world study will test whether an AI system can predict which patients with locally advanced gastric cancer will respond to neoadjuvant chemotherapy plus PD-1 inhibitors before surgery.

  Recruiting at 9 sites Hebei Medical University · Fuyang, Anhui and 8 other locations · NCT07401199

• SH009 injection for advanced solid tumors

  This trial will test whether SH009 injections are safe and can shrink or slow advanced solid tumors in adults with cancers such as liver, lung, breast, head and neck, and esophageal cancer who have progressed after prior treatment.

  Recruiting Phase 1 Nanjing Sanhome Pharmaceutical, Co., Ltd. · Shanghai · NCT07390838

• Comparing oxaliplatin plus S-1 versus docetaxel plus S-1 after surgery for stage III stomach cancer

  This trial tests whether oxaliplatin plus S-1 or docetaxel plus S-1 is better at preventing cancer recurrence in people with stage III gastric cancer after D2 gastrectomy.

  Recruiting Phase 3 Ruijin Hospital · Shaoguan, Guandong and 4 other locations · NCT07366528

• QL1706 (Iparomlimab + Tuvonralimab) with SOX chemotherapy for untreated advanced or metastatic gastric or gastroesophageal junction cancer

  This trial will test whether adding QL1706 (two immunotherapy drugs) to SOX chemotherapy helps people with previously untreated advanced or metastatic gastric or gastroesophageal junction cancer get a better tumor response.

  Recruiting Phase 2 Beijing Friendship Hospital · Beijing, Beijing Municipality · NCT07315854

• HIPEC during curative gastrectomy for advanced or low‑volume metastatic gastric cancer

  This tests whether adding a single heated dose of chemotherapy inside the abdomen (HIPEC) during curative gastrectomy helps people with T4 tumors or low‑volume peritoneal gastric cancer.

  Recruiting Ukrainian Society of Clinical Oncology · Kyiv · NCT07313579

• SHR-1701 plus rivoceranib (with or without SHR-2554) for advanced gastric and gastroesophageal junction adenocarcinoma after first-line immunotherapy

  This will see if combining SHR-1701 with rivoceranib, with or without SHR-2554, helps people with advanced gastric or gastroesophageal junction cancer whose disease progressed on or who couldn't tolerate first-line immunotherapy.

  Recruiting Phase 2 China Medical University, China · Shenyang, Liaoning · NCT07311408

• Noninvasive blood miRNA test to screen for multiple gastrointestinal cancers.

  This project will test whether a blood-based microRNA panel can detect several types of gastrointestinal cancer in adults using stored blood samples.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07224750

• 18F-FAPI PET/CT to find spread of stomach or esophageal cancer

  We will test whether a single [18F]FAPI-74 PET/CT scan can find metastatic disease in adults with confirmed gastric, gastroesophageal junction, or esophageal cancer.

  Recruiting at 17 sites Phase 3 Sofie · Cerritos, California and 18 other locations · NCT07217704

• Defining how much No.4sb lymph node to remove for advanced distal stomach cancer

  This project will try to find the best range of No.4sb lymph node removal during surgery for people with locally advanced distal stomach cancer.

  Recruiting Tianjin Medical University Cancer Institute and Hospital · Tianjin, Tianjin Municipality · NCT07183150

• NK510 for advanced gastric and colorectal cancer (early phase 1)

  A first-in-human-type trial will test NK510 in adults with advanced stomach or colon/rectal cancer that has not responded to multiple treatments.

  Recruiting Early Phase 1 Base Therapeutics (Shanghai) Co., Ltd. · Nanjing, Jiangsu · NCT07166263

• Neoadjuvant radiotherapy plus SOX chemotherapy with Iparomlimab and Tuvonralimab for resectable gastric and gastroesophageal junction adenocarcinoma

  This trial will test whether adding radiotherapy to pre-surgery SOX chemotherapy plus two immunotherapy drugs (Iparomlimab and Tuvonralimab) helps people with resectable, HER2‑negative gastric or gastroesophageal junction cancer.

  Recruiting Phase 2 Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Chongqing, Other (Non U.s.) · NCT07165847

• Investigating OKN4395 and Pembrolizumab for Solid Tumors

  This study is testing a new drug called OKN4395, alone and with another drug called pembrolizumab, to see if it can help people with solid tumors who have run out of other treatment options.

  Recruiting at 10 sites Phase 1 Epkin · Beverly Hills, California and 9 other locations · NCT06789172

• Comparing two imaging techniques for gastrointestinal surgeries

  This study is testing two different imaging methods to see which one better helps doctors check blood flow in patients who have had gastrointestinal surgeries.

  Recruiting at 2 sites Saint Petersburg State University, Russia · Yantai, Shandong and 2 other locations · NCT06222645

Related topics

Quick answers

How many Gastric Cancer (GC) clinical trials are recruiting right now?

30, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in China (17 trials), United States (7 trials), Russia (2 trials), Italy (2 trials), Belgium (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 7, Phase 2: 6, Phase 3: 2, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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