Cleansing options to improve colonoscopy tolerance
Official title: Cleansing Options in Outpatient Setting to Improve Tolerance (COOP SIT) Trial
Run by Morehouse School of Medicine · NCT07215000 · Data updated 2026-11-12
This test compares low-volume tablet bowel preps (Sutab/Suflave) with standard Golytely for adults having outpatient colonoscopies to see which is better tolerated and preferred.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Morehouse School of Medicine Academic / other |
| Locations | 1 site (Atlanta, Georgia) |
| Status | Recruiting |
| Started | October 1, 2025 |
| Main results expected | January 2027 |
| Study ends | June 2027 |
| Registry record updated | October 9, 2025 |
| Trial ID | NCT07215000 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 and older scheduled for outpatient colonoscopy who can provide informed consent in English or Spanish are ideal candidates.
✕Probably not a fit
Pregnant or nursing people, those under 18, incarcerated individuals, or anyone unable to give informed consent would not be eligible and thus would not benefit from participating.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
About 300 adults scheduled for outpatient colonoscopy will be randomized in a 2:1 ratio to receive either a low-volume tablet preparation (Sutab/Suflave) or standard polyethylene glycol solution (Golytely). Participants will complete brief surveys before and after their procedures over a 12-month enrollment period to capture completion rates, satisfaction, and tolerability. Endoscopists will rate bowel cleanliness to compare the endoscopic adequacy of each method. The trial will compare patient-reported experience and objective cleansing outcomes between the two prep strategies.
Why it matters
Potential benefit: If successful, a more tolerable prep could make bowel cleansing easier, increase completion rates, and improve the quality of colonoscopy screenings.
How similar studies have gone: Prior trials have shown low-volume tablet preps like Sutab can provide similar cleansing efficacy to PEG solutions and are often better tolerated and preferred by patients.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults over age of 18 years undergoing outpatient colonoscopy for various indications, ability to consent in English or Spanish. Patients will still be allowed to join if there is a history of colorectal cancer or previous surgery Exclusion Criteria: * Patient is less than 18 years of age, any pregnant or nursing women, unable to consent, or patient is incarcerated.
Where it's running
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Morehouse School of Medicine
Atlanta, Georgia, United States Recruiting
Study contacts
- Principal investigator: Jesus M Luevano, MD, MS — Morehouse School of Medicine
- Study coordinator: Julia J Liu, MD, MSc
- Email: jjliu@msm.edu
- Phone: (404) 756-1369
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.