Clinical trial Recruiting at 1 site Phase 4 Interventional Ages 18 and up

Cleansing options to improve colonoscopy tolerance

Official title: Cleansing Options in Outpatient Setting to Improve Tolerance (COOP SIT) Trial

Run by Morehouse School of Medicine · NCT07215000 · Data updated 2026-11-12

This test compares low-volume tablet bowel preps (Sutab/Suflave) with standard Golytely for adults having outpatient colonoscopies to see which is better tolerated and preferred.

Quick facts

PhasePhase 4
Study typeInterventional
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorMorehouse School of Medicine
Academic / other
Locations1 site (Atlanta, Georgia)
StatusRecruiting
StartedOctober 1, 2025
Main results expectedJanuary 2027
Study endsJune 2027
Registry record updatedOctober 9, 2025
Trial IDNCT07215000 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18 and older scheduled for outpatient colonoscopy who can provide informed consent in English or Spanish are ideal candidates.

Probably not a fit

Pregnant or nursing people, those under 18, incarcerated individuals, or anyone unable to give informed consent would not be eligible and thus would not benefit from participating.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

About 300 adults scheduled for outpatient colonoscopy will be randomized in a 2:1 ratio to receive either a low-volume tablet preparation (Sutab/Suflave) or standard polyethylene glycol solution (Golytely). Participants will complete brief surveys before and after their procedures over a 12-month enrollment period to capture completion rates, satisfaction, and tolerability. Endoscopists will rate bowel cleanliness to compare the endoscopic adequacy of each method. The trial will compare patient-reported experience and objective cleansing outcomes between the two prep strategies.

Why it matters

Potential benefit: If successful, a more tolerable prep could make bowel cleansing easier, increase completion rates, and improve the quality of colonoscopy screenings.

How similar studies have gone: Prior trials have shown low-volume tablet preps like Sutab can provide similar cleansing efficacy to PEG solutions and are often better tolerated and preferred by patients.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults over age of 18 years undergoing outpatient colonoscopy for various indications, ability to consent in English or Spanish. Patients will still be allowed to join if there is a history of colorectal cancer or previous surgery

Exclusion Criteria:

* Patient is less than 18 years of age, any pregnant or nursing women, unable to consent, or patient is incarcerated.

Where it's running

  • Morehouse School of Medicine
    Atlanta, Georgia, United States
    Recruiting

Study contacts

  • Principal investigator: Jesus M Luevano, MD, MS — Morehouse School of Medicine
  • Study coordinator: Julia J Liu, MD, MSc
  • Email: jjliu@msm.edu
  • Phone: (404) 756-1369

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.