Increasing follow-up colonoscopies after a positive FIT in community clinics
Official title: Evaluating a Multilevel Intervention to Increase Colonoscopic Follow-up after Abnormal Stool-based Colorectal Cancer Screening in a Community Safety-Net Setting
Funded at University of California Los Angeles · NIH-11399152 · Data updated 2026-11-12
Aims to help people with abnormal stool tests for colorectal cancer get timely follow-up colonoscopies in safety-net clinics.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 5, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $1,820,245 |
| NIH project number | 4R01CA292236-03 |
| Project ID | NIH-11399152 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults receiving FIT screening at participating FQHCs who have an abnormal FIT result and are eligible for colonoscopy.
✕Less likely to help
Patients who do not experience barriers to follow-up or who choose not to undergo colonoscopy may derive little direct benefit.
What this research studies
This project tests a multilevel approach to boost the odds that individuals with a positive FIT will complete a colonoscopy in Federally Qualified Health Centers. It uses a cluster-randomized design across clinics to identify strategies that work in real-world, resource-limited settings. The focus is on practical teamwork, patient navigation, and system changes that can be adopted in community care to reduce delays in follow-up care. The study will occur in safety-net settings in Los Angeles, involving patients who have had abnormal stool tests.
Why it matters
Potential benefit: If successful, patients with abnormal FIT results could receive timely colonoscopies, reducing the risk of missed cancers and improving survival.
How similar studies have gone: Previous work has shown that targeted interventions can improve follow-up rates, but results vary by setting; this study tests a multilevel approach in safety-net clinics.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: May, Folasade Popoola — University of California Los Angeles
- Study coordinator: May, Folasade Popoola
Related research
Other NIH-funded projects on the same topics.
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Improving colorectal cancer screening and follow-up care.
This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.
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Making colorectal cancer screening easier and more likely to happen
This project uses default options, simpler choices, and direct outreach to help average-risk adults who are overdue complete colorectal cancer screening with colonoscopy or stool tests.
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AI/AN Tailoring of a Home-Based Cervical and Colorectal Cancer Screening Program
A tailored, home-based cancer screening program helps AI/AN adults screen for cervical and colorectal cancer from home using self-collection tests and culturally aligned education.
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Bringing colorectal cancer screening to adults 45–54 who haven’t been screened
A grant to help low-income adults aged 45–54 start colorectal cancer screening through the Boston area’s community health centers.
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Colorectal cancer screening with real-time imaging that may replace sedated scopes
Researchers are testing a new imaging method called optical coherence tomography (OCT) to spot and treat colon polyps without the need for sedation during a screening colonoscopy.
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Promoting follow-up after abnormal colorectal cancer screening in safety-net systems
A multilevel program will help people in safety-net hospitals complete follow-up colonoscopy after an abnormal stool test.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.