Does GP endorsement and early information improve colonoscopy follow-up after a positive colorectal cancer screening test?
Official title: EFFECTIVENESS OF EARLY INFORMATION AND ENDORSMENT BY GP TO INCREASE COLONOSCOPY FOLLOW-UP AND REDUCE DELAYS IN PEOPLE WITH A POSITIVE COLORECTAL CANCER SCREENING TEST, A RANDOMISED CONTROLLED TRIAL. (SUIVICOLO)
Run by University Hospital, Caen · NCT07520578 · Data updated 2026-11-12
This study tests whether giving patients early information about colonoscopy and having their GP endorse the follow-up can increase how many people in France get a colonoscopy within six months after a positive screening result.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 50 Years to 75 Years |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | University Hospital, Caen Academic / other |
| Locations | 1 site (Tours, France) |
| Status | Recruiting |
| Started | March 24, 2026 |
| Main results expected | March 24, 2027 |
| Study ends | October 24, 2028 |
| Registry record updated | September 18, 2026 |
| Trial ID | NCT07520578 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 50–75 with a recent positive screening result, living in Centre Val de Loire, and enrolled with a health insurance fund.
✕Probably not a fit
Patients without access to primary care or with contraindications to colonoscopy may see no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In France, many people with a positive colorectal cancer screening test delay or miss diagnostic colonoscopy. This phase 3 interventional study compares usual follow-up with two enhanced approaches: an information leaflet about colonoscopy follow-up and a GP endorsement of the CRCDC follow-up letters. The goal is to increase the rate of completed colonoscopies at six months. Participants are adults 50–75 with a recent positive screening result and residing in the Centre Val de Loire region. Outcomes focus on follow-up adherence and timeliness of diagnostic colonoscopy.
Why it matters
Potential benefit: If successful, the strategies could lead to more timely diagnostic colonoscopies and earlier detection of colorectal cancer.
How similar studies have gone: Prior work in screening programs suggests that targeted information and physician endorsement can improve follow-up rates, but effectiveness may vary by setting.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged between 50 and 75 at the time of the positive colorectal cancer screening test * Residing in one of the departments of the Centre Val de Loire region * Date on which the positive CRC screening test result was sent to the beneficiary recorded * Colorectal cancer screening test results sent to the beneficiary within 30 days of the test being read * Affiliated with a health insurance fund Exclusion Criteria: * Subjects who have notified their refusal to allow their data to be used for research purposes will be excluded from the analyses.
Where it's running
-
Crcdc-Cvl
Tours, France, France Recruiting
Study contacts
- Study coordinator: Lydia GUITTET, MD,PhD
- Email: lydia.guittet@unicaen.fr
- Phone: 231065781
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.