Clinical trial Recruiting at 1 site Phase 3 Interventional Ages 50 to 75

Does GP endorsement and early information improve colonoscopy follow-up after a positive colorectal cancer screening test?

Official title: EFFECTIVENESS OF EARLY INFORMATION AND ENDORSMENT BY GP TO INCREASE COLONOSCOPY FOLLOW-UP AND REDUCE DELAYS IN PEOPLE WITH A POSITIVE COLORECTAL CANCER SCREENING TEST, A RANDOMISED CONTROLLED TRIAL. (SUIVICOLO)

Run by University Hospital, Caen · NCT07520578 · Data updated 2026-11-12

This study tests whether giving patients early information about colonoscopy and having their GP endorse the follow-up can increase how many people in France get a colonoscopy within six months after a positive screening result.

More Colorectal Cancer Screening trials

Quick facts

PhasePhase 3
Study typeInterventional
Ages50 Years to 75 Years
SexAll
Enrollment2000 (estimated)
SponsorUniversity Hospital, Caen
Academic / other
Locations1 site (Tours, France)
StatusRecruiting
StartedMarch 24, 2026
Main results expectedMarch 24, 2027
Study endsOctober 24, 2028
Registry record updatedSeptember 18, 2026
Trial IDNCT07520578 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 50–75 with a recent positive screening result, living in Centre Val de Loire, and enrolled with a health insurance fund.

Probably not a fit

Patients without access to primary care or with contraindications to colonoscopy may see no benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In France, many people with a positive colorectal cancer screening test delay or miss diagnostic colonoscopy. This phase 3 interventional study compares usual follow-up with two enhanced approaches: an information leaflet about colonoscopy follow-up and a GP endorsement of the CRCDC follow-up letters. The goal is to increase the rate of completed colonoscopies at six months. Participants are adults 50–75 with a recent positive screening result and residing in the Centre Val de Loire region. Outcomes focus on follow-up adherence and timeliness of diagnostic colonoscopy.

Why it matters

Potential benefit: If successful, the strategies could lead to more timely diagnostic colonoscopies and earlier detection of colorectal cancer.

How similar studies have gone: Prior work in screening programs suggests that targeted information and physician endorsement can improve follow-up rates, but effectiveness may vary by setting.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged between 50 and 75 at the time of the positive colorectal cancer screening test

  * Residing in one of the departments of the Centre Val de Loire region
  * Date on which the positive CRC screening test result was sent to the beneficiary recorded
  * Colorectal cancer screening test results sent to the beneficiary within 30 days of the test being read
  * Affiliated with a health insurance fund

Exclusion Criteria:

* Subjects who have notified their refusal to allow their data to be used for research purposes will be excluded from the analyses.

Where it's running

  • Crcdc-Cvl
    Tours, France, France
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.