Using prior CT scans to guide colonoscope insertion
Official title: The Impact of Image-Assisted Colonoscope on Patient Experience, Physician Workload, and Examination Quality
Run by Peking Union Medical College Hospital · NCT07541924 · Data updated 2026-11-12
This trial will test whether using a patient's existing abdominal/pelvic CT scan to guide colonoscope insertion makes colonoscopy faster and more comfortable for adults having screening or diagnostic colonoscopy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Peking Union Medical College Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | December 9, 2025 |
| Main results expected | January 30, 2026 |
| Study ends | May 28, 2026 |
| Registry record updated | April 21, 2026 |
| Trial ID | NCT07541924 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–80 undergoing colonoscopy at Peking Union Medical College Hospital who have an abdominal/pelvic CT from within the past 5 years and no major abdominal surgery afterward are ideal candidates.
✕Probably not a fit
Patients without a usable CT within 5 years, those with prior colonic resections that alter anatomy, and those with severe cardiopulmonary dysfunction, coagulopathy, or pregnancy are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-blind, randomized controlled trial at Peking Union Medical College Hospital will randomize 140 participants 1:1 to image-assisted insertion based on a prior abdominal/pelvic CT (≤5 years) or to standard insertion. The primary outcome is cecal intubation time, with secondary outcomes including patient-reported pain (VAS), willingness for future colonoscopy, operator workload (NASA-TLX), looping events, total procedure time, and polyp detection rate. Operators will record procedural findings and investigators will compare those findings with CT-based anatomical predictions to measure consistency and feasibility. The trial aims to provide prospective evidence on whether individualized, anatomy-informed insertion strategies improve examination quality and patient experience.
Why it matters
Potential benefit: If successful, this approach could shorten insertion time, reduce patient discomfort and operator workload, and improve overall exam quality and polyp detection.
How similar studies have gone: Retrospective CT-based analyses and fluoroscopy-guided maneuvers have suggested anatomical guidance can reduce looping and procedural difficulty, but prospective randomized evidence is currently lacking.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-80 years, or expected natural survival \>3 years * Undergoing colonoscopy at Peking Union Medical College Hospital * Presence of an abdominal/pelvic CT scan performed within ≤5 years and no - - - major abdominal surgery afterward * Patient or legal guardian able to understand the study and provide written consent Exclusion Criteria: * No available CT or CT quality insufficient for anatomical evaluation * Prior colonic surgery affecting anatomy (e.g., right hemicolectomy, transverse colectomy) * Severe cardiopulmonary dysfunction or coagulopathy * Pregnancy * Refusal to participate or inability to complete questionnaires * Patient or guardian unable to understand study requirements
Where it's running
-
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Study coordinator: Kun He, MD
- Email: hk6290418@163.com
- Phone: 15901623698
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.