Condition

Colon Adenocarcinoma clinical trials and research

• 12Clinical trials
• 31Countries

Newest Colon Adenocarcinoma clinical trials

All recruiting trials (12)

• Postoperative ctDNA Monitoring to Predict Recurrence in Driver-Mutant Stage I-III Colon Cancer

  This study tests whether checking blood tumor DNA after surgery can predict if driver-mutant stage I-III colon cancer will come back.

  Recruiting Ruijin Hospital · Shanghai, Shanghai Municipality · NCT07795528

• Adding tolecizumab to chemoimmunotherapy before surgery for locally advanced pMMR/MSS colon cancer

  We're testing whether adding tolecizumab (a PCSK9 blocker) to sintilimab plus CapeOX before surgery helps people with pMMR/MSS locally advanced colon cancer (cT3c or higher) achieve a complete tumor response.

  Recruiting Phase 2 Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Chongqing, Chongqing Municipality · NCT07468630

• Family genetics: who shares test results with relatives

  This study tests whether letting patients share genetic results with their relatives is as good as doctors sharing the results to help first-degree relatives get genetic testing for hereditary cancer risk.

  Recruiting at 362 sites Alliance for Clinical Trials in Oncology · Birmingham, Alabama and 364 other locations · NCT07143487

• Calderasib plus cetuximab and chemotherapy for KRAS G12C colorectal cancer

  This trial will test whether adding calderasib and cetuximab to mFOLFOX6 helps people with unresectable locally advanced or metastatic colorectal cancer that has a KRAS G12C mutation live longer without their cancer growing.

  Recruiting at 244 sites Phase 3 Merck Sharp & Dohme LLC · Phoenix, Arizona and 244 other locations · NCT06997497

• Testing a new stool test for colorectal cancer detection

  This study is testing a new stool test to see if it can help find colorectal cancer and advanced growths in people aged 45 and older who are at average risk.

  Recruiting Mainz Biomed · Morrisville, North Carolina · NCT06864338

• Elderly patients with metastatic colorectal cancer: first-line reduced-dose chemo plus targeted antibody

  This retrospective study looks at whether starting older patients (70+) on a reduced-dose doublet chemotherapy combined with a full-dose monoclonal antibody can be feasible in first-line treatment for metastatic colorectal cancer.

  Recruiting Ente Ospedaliero Ospedali Galliera · Genova, GE and 1 other locations · NCT06840977

• Using HDAC inhibitors with chemoimmunotherapy for advanced colon cancer treatment

  This study is testing if adding HDAC inhibitors to chemotherapy and immunotherapy can help people with advanced colon cancer have better treatment results and improve their chances of recovery.

  Recruiting Phase 2 Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Chongqing, Chongqing Municipality · NCT06709885

• Evaluating PreveCol for Early Detection of Colorectal Cancer

  This study is testing a new blood test called PreveCol to see if it can help find colorectal cancer and advanced polyps in people aged 50-69 who have already had a positive stool test.

  Recruiting Advanced Marker Discovery S.l. · Lisbon, Lisbon District and 1 other locations · NCT06703632

• Minimally invasive surgery for early-stage colon cancer

  This study is testing a new, less invasive surgery for early-stage colon cancer to see if it can lower the chances of cancer coming back compared to the standard surgery.

  Recruiting Meander Medical Center · Amersfoort · NCT06652672

• Living donor liver transplant for patients with non-resectable colorectal cancer liver metastasis

  This study is testing whether living donor liver transplants can help patients with colorectal cancer that has spread to the liver live longer and healthier lives.

  Recruiting Azienda Ospedaliero-Universitaria di Modena · Modena, MO · NCT05186116

• Observing cancer recurrence using a blood test

  This study is testing a new blood test to see if it can help find out if cancer comes back in people who have been treated for early-stage solid tumors.

  Recruiting at 49 sites Guardant Health, Inc. · Birmingham, Alabama and 56 other locations · NCT05059444

• Using ctDNA to guide treatment changes for colon cancer

  This study is testing if a new combination of cancer treatments can help people with colon cancer who still have traces of the disease after surgery feel better and live longer.

  Recruiting Phase 1 University of California, Irvine · Orange, California · NCT04920032

Related topics

Quick answers

How many Colon Adenocarcinoma clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 31 countries. The most sites are in United States (5 trials), Italy (4 trials), China (4 trials), Spain (3 trials), France (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 3: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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