Closing the gap between a positive FIT test and diagnostic colonoscopy
Official title: Fit Abnormal to Colonoscopy: Equity in Screening Completion (FACES)
Run by Massachusetts General Hospital · NCT06763432 · Data updated 2026-11-12
This project will test patient- and system-level strategies to increase follow-up colonoscopy after a positive FIT for patients aged 45–75 at a Boston community health center.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 45 Years to 75 Years |
| Sex | All |
| Enrollment | 45 (estimated) |
| Sponsor | Massachusetts General Hospital Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Status | Recruiting |
| Started | June 16, 2025 |
| Main results expected | August 31, 2029 |
| Study ends | August 31, 2029 |
| Registry record updated | November 13, 2025 |
| Trial ID | NCT06763432 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients aged 45–75 who receive care at Codman Square Health Center and are willing to provide consent, especially those with a recent positive FIT or who are due for colorectal cancer screening.
✕Probably not a fit
Patients with a personal or family history of colorectal cancer, inflammatory bowel disease, high-risk cancer syndromes, or those not receiving care at Codman Square or unwilling to consent are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The project uses mixed methods guided by the Consolidated Framework for Implementation Research (CFIR 2.0) to identify patient- and system-level determinants of follow-up colonoscopy after a positive FIT. Investigators will develop equity-driven implementation strategies matched to those determinants and pilot them at Codman Square Health Center. Pilot outcomes and feasibility will be measured using the RE-AIM framework with an explicit equity lens. The setting focuses on a predominantly Black, low-income clinic population with historically low screening and follow-up rates.
Why it matters
Potential benefit: If successful, these strategies could increase timely diagnostic colonoscopy after positive FIT and help reduce colorectal cancer disparities in this high-risk community.
How similar studies have gone: Previous implementation efforts and patient-navigation interventions have improved screening and follow-up in some settings, but follow-up after positive FIT remains variable and often insufficient, so results have been mixed.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals aged 45-75 * Individuals who are patients at Codman Square Health Center * Individuals that are willing and able to give verbal/written consent Exclusion Criteria: * Individuals with a personal history of colorectal cancer * Individuals with a family history of colorectal cancer * Individuals with a history of inflammatory bowel disease or high-risk cancer syndrome
Where it's running
-
Codman Square Health Center
Boston, Massachusetts, United States Recruiting
Study contacts
- Study coordinator: Adjoa Anyane-Yeboa, MD, MPH
- Email: aanyane-yeboa@mgh.harvard.edu
- Phone: 617-726-6609
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.