Improving colorectal cancer screening for Alaska Native people using a new stool DNA test

Randomized controlled trial of the stool DNA test to improve colorectal cancer screening among Alaska Native people

NIH-funded research Alaska Native Tribal Health Consortium · NIH-10918041

This study is looking at a new at-home stool DNA test for colorectal cancer to see if it can help more people in Alaska Native communities get screened and reduce cancer deaths, all while working closely with local health organizations to make sure it fits their needs.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionAlaska Native Tribal Health Consortium NIH-funded
Lab location1 site (Anchorage, United States)
Project IDNIH-10918041 on NIH RePORTER

What this research studies

This research investigates the effectiveness of a new at-home stool DNA screening test for colorectal cancer (CRC) among Alaska Native communities, where screening rates are notably low. The study aims to determine if this test can increase screening participation and ultimately reduce CRC-related deaths. It employs a community-based participatory research approach, collaborating with local Tribal health organizations to ensure the research is culturally appropriate and relevant. The research will assess the feasibility and acceptability of the test within the unique healthcare delivery system of Alaska Native populations.

Who could benefit from this research

Good fit: Ideal candidates for this research are Alaska Native individuals who are eligible for colorectal cancer screening.

Not a fit: Patients who are not Alaska Native or those who have already been adequately screened for colorectal cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly increase colorectal cancer screening rates among Alaska Native people, leading to earlier detection and improved survival rates.

How similar studies have performed: While the stool DNA test has shown promise in other populations, this specific application within Alaska Native communities is novel and has not been previously tested.

Where this research is happening

Anchorage, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.