Increasing colonoscopy follow‑up after a positive stool colorectal screening at community health clinics

Evaluating a Multilevel Intervention to Increase Colonoscopic Follow-up after Abnormal Stool-based Colorectal Cancer Screening in a Community Safety-Net Setting

NIH-funded research University of California Los Angeles · NIH-11184329

This project tests clinic‑level and patient supports to help people at community health centers get timely colonoscopies after a positive stool-based colorectal cancer screening.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-11184329 on NIH RePORTER

What this research studies

If you receive a positive stool-based colorectal cancer test (FIT) at a community clinic, this project offers extra clinic and patient supports aimed at helping you complete a colonoscopy. The team is using a cluster-randomized approach where whole clinics are assigned to deliver the multilevel intervention or usual care, and they will track patients' follow-up rates and timing. The intervention includes workflow changes, outreach from clinic staff or navigators, reminders, and help addressing barriers such as scheduling, insurance, and transportation. Data will come from clinic records and follow-up contact to see whether these practical changes improve timely colonoscopy completion in low-resource settings.

Who could benefit from this research

Good fit: Adults receiving care at participating Federally Qualified Health Centers who have an abnormal/positive stool-based colorectal cancer screening test and need a follow-up colonoscopy.

Not a fit: People without a positive stool test, those already up-to-date with colonoscopy, or patients who do not receive care at participating clinics are unlikely to benefit directly from this project.

Why it matters

Potential benefit: If successful, this could increase timely colonoscopies after a positive stool test and help catch colorectal problems earlier when they are easier to treat.

How similar studies have performed: Previous programs using patient navigation and multilevel supports have improved follow-up in some health systems, but results have varied and few trials have tested these approaches in safety-net FQHC settings.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer BurdenCancer CauseCancer Control ResearchCancer EtiologyCancers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.