Improving colorectal cancer screening using advanced imaging technology
Colorectal Cancer Screening with Optical Coherence Tomography
This study is testing a new imaging technology called optical coherence tomography (OCT) to make colorectal cancer screenings better by helping doctors see hard-to-reach areas in the colon, which could lead to more accurate polyp detection and a more comfortable, less invasive experience for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10979884 on NIH RePORTER |
What this research studies
This research focuses on enhancing colorectal cancer screening by utilizing optical coherence tomography (OCT), a cutting-edge imaging technology. The goal is to develop a system that allows for better visualization of the entire colon, including areas that are typically hard to see, such as behind mucosal folds. By improving the sensitivity and accuracy of polyp detection, this approach aims to reduce the number of missed adenomas and the associated costs of traditional colonoscopy procedures. Patients may benefit from a less invasive screening method that does not require sedation and can provide real-time diagnosis.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals undergoing routine colorectal cancer screening, particularly those at higher risk for adenomas.
Not a fit: Patients who have already been diagnosed with colorectal cancer or those who are not eligible for screening may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and cost-effective colorectal cancer screenings, ultimately reducing cancer incidence and improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using advanced imaging technologies for cancer detection, indicating that this approach could be a significant advancement in colorectal cancer screening.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Tearney, Guillermo J — Massachusetts General Hospital
- Study coordinator: Tearney, Guillermo J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.