Improving colorectal cancer screening using behavioral economics

Behavioral Economic Approaches for Population-based Colorectal Cancer Screening

NIH-funded research University of Pennsylvania · NIH-11212487

This study is looking to improve how many people get screened for colorectal cancer by using friendly reminders from doctors and reaching out directly to patients, and it will compare two options for screening: getting a colonoscopy right away or starting with a simpler test first, for those who might want to wait.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11212487 on NIH RePORTER

What this research studies

This research aims to enhance colorectal cancer screening rates by applying behavioral economic principles. It will evaluate a multi-level intervention that includes clinician-directed nudges through electronic health records and direct outreach to patients. The study will compare the effectiveness of offering colonoscopy only versus a sequential choice of colonoscopy followed by a fecal immunochemical test (FIT) for those who defer. Conducted across 30 diverse primary care practices, the trial will involve approximately 20,000 average-risk patients who are overdue for screening.

Who could benefit from this research

Good fit: Ideal candidates for this research are average-risk adults who are overdue for colorectal cancer screening.

Not a fit: Patients who are already up-to-date with their colorectal cancer screenings or those with a high risk of colorectal cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly increase colorectal cancer screening rates, leading to earlier detection and improved patient outcomes.

How similar studies have performed: Previous research has shown that behavioral economic strategies can effectively improve health screening rates, suggesting a promising approach in this context.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer CauseCancer EtiologyColorectal Cancercolorectal cancer detection
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.