Condition

Bronchiectasis clinical trials and research

• 44Clinical trials
• 5NIH research projects
• 1New in 30 days
• 43Countries

Newest Bronchiectasis clinical trials

All recruiting trials (44)

• Chronic Respiratory Disease Participant Engagement

  This study tests whether adults with long-term lung conditions can get comfortable with a clinical trials unit and research team before joining future trials.

  Recruiting Richmond Pharmacology Limited · London · NCT07924462

• Breathlessness in respiratory diseases: who feels it and why

  This study tests how physiology, psychology, function, and breathing patterns relate to breathlessness in people with respiratory conditions compared with healthy controls.

  Recruiting University Hospitals, Leicester · Leicester, Leicestershire · NCT07648082

• Hypertonic saline inhalation for NTM lung disease

  This trial tests whether starting inhaled 3% hypertonic saline early helps people with non-tuberculous mycobacterial lung disease feel better and clear bacteria better, compared with starting with normal saline first.

  Recruiting Taipei Veterans General Hospital, Taiwan · Taipei · NCT07647575

• Azithromycin added to usual care to see if it lowers bronchiectasis flare-ups

  This trial tests whether taking azithromycin daily for a year reduces bronchiectasis-related flare-ups in adults with non-cystic fibrosis bronchiectasis.

  Recruiting Phase 4 Assiut University · Asyut · NCT07608328

• Bronchiectasis Phenotype Identification Model for Adults

  This study tests a baseline classifier to categorize adults with non-cystic fibrosis bronchiectasis into phenotype groups using data collected over time.

  Recruiting Assiut University · Asyut, Assiut Egypt · NCT07599969

• BASE: Aiming to test a simple, objective way to gauge bronchiectasis severity and predict flare-ups

  This study tests a new BASE framework to classify how severe non-cystic fibrosis bronchiectasis is right now and see if it can predict 12 months of worsening or flare-ups.

  Recruiting Assiut University · Asyut, Asyut Egypt · NCT07599839

• Immune status and disease control in airway inflammatory diseases

  This project will test whether specific blood immune cell patterns relate to disease control in adults with asthma, COPD, bronchiectasis, or obstructive sleep apnea by comparing them with healthy volunteers.

  Recruiting First Affiliated Hospital of Ningbo University · Ningbo, Zhejiang · NCT07493629

• How environmental fungal exposure affects asthma, ABPA, and bronchiectasis

  This project will see if indoor and environmental fungal exposure is linked to disease control in adults with asthma, ABPA, or bronchiectasis and will compare findings to healthy adults.

  Recruiting First Affiliated Hospital of Ningbo University · Ningbo, Zhejiang · NCT07313904

• Itraconazole for bronchiectasis with airway mold

  This study will try oral itraconazole in adults with bronchiectasis who have mold in their airways to see if people can take it safely and whether it changes symptoms and airway microbes.

  Recruiting Phase 4 Mayo Clinic · Rochester, Minnesota · NCT07283497

• PALMIRE cohort: phenotyping inflammatory lung diseases to enable personalized care

  This project will collect clinical, imaging, and biological data from adults with asthma, COPD, bronchiectasis, cystic fibrosis, primary ciliary dyskinesia, or interstitial lung disease to try to identify disease subtypes and markers that could guide more personalized care.

  Recruiting CHU de Reims · Reims · NCT07274631

• GSK's new drug for adults with bronchiectasis

  A new drug (GSK3862995B) is being tested in adults with bronchiectasis to see if it works better than placebo and to check safety and how the body handles it.

  Recruiting at 134 sites Phase 2 GlaxoSmithKline · Mobile, Alabama and 133 other locations · NCT07201051

• Health impact of non-tuberculous mycobacteria (NTM) lung disease

  This project will try to see which symptoms matter most and which non-drug treatments help adults with NTM lung disease.

  Recruiting University College, London · London · NCT07192705

• Inspiratory muscle training to improve breathing and core stability in bronchiectasis

  This trial tests whether a program of functional inspiratory muscle training can help adults aged 18–30 with bronchiectasis strengthen their breathing muscles and improve respiratory function and core stability.

  Recruiting Istinye University · Istanbul · NCT07188675

• Bailing Capsules with Guben Kechuan Granules for stable bronchiectasis

  This trial will try whether adding Bailing Capsules plus Guben Kechuan Granules to standard Western treatment reduces acute exacerbations in adults with stable bronchiectasis.

  Recruiting Phase 4 Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang and 4 other locations · NCT07114120

• Expiratory (breathing-out) muscle strength and health outcomes in bronchiectasis

  This project tests whether weaker expiratory (breathing-out) muscles are linked to worse symptoms, more hospital visits, and lower quality of life in adults with non‑cystic fibrosis bronchiectasis.

  Recruiting Saglik Bilimleri Universitesi · Istanbul · NCT07104942

• Shuttle Walking Test to predict breathing problems after lung surgery

  This project will use a simple shuttle walking test before lung surgery to see if it predicts breathing problems and quality-of-life changes in people with chronic lung disease.

  Recruiting Seoul National University Bundang Hospital · Seongnam-si, Not Required For This Country · NCT07102589

• Using entropy to detect sleep breathing problems in chronic lung disease

  This project will test whether entropy measurements from simple overnight oxygen and pulse recordings can find sleep-disordered breathing in adults with chronic lung conditions such as COPD, asthma, bronchiectasis, and interstitial lung disease.

  Recruiting University College, London · London · NCT07060079

• Using the Lung Sliding Index to distinguish common lung diseases

  This project will test whether the Lung Sliding Index (LSI) measured by bedside ultrasound can tell apart various lung conditions in adults with lung disease and in healthy volunteers.

  Recruiting Assiut University · Asyut · NCT06983366

• Home OLE (oscillating lung expansion) therapy with BiWaze Clear for bronchiectasis

  This study will see if using the BiWaze Clear home therapy for six months helps people with bronchiectasis have fewer pulmonary exacerbations.

  Recruiting at 5 sites Delve Health · New Haven, Connecticut and 4 other locations · NCT06926881

• Interactive digital breathing game and device for children with bronchiectasis

  We will test an interactive digital breathing game and paired device to help children aged 7–18 with bronchiectasis do airway-clearing exercises at home without a physiotherapist.

  Recruiting Atlas University · Istanbul · NCT06897761

• BI 1291583 for people with bronchiectasis

  This study will test whether a once-daily pill called BI 1291583 can reduce flare-ups in people aged 12 and older who have bronchiectasis and produce sputum.

  Recruiting at 244 sites Phase 3 Boehringer Ingelheim · Birmingham, Alabama and 477 other locations · NCT06872892

• Assessing quality of life in patients with bronchiectasis using oscillating PEP devices

  This study is testing if using an oscillating PEP device can improve the daily lives and well-being of children and adults with bronchiectasis who aren't currently using one.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT06820983

• Understanding the impact of multimorbidity on chronic airway diseases

  This study looks at how having multiple health issues affects people with chronic lung diseases like COPD, asthma, or bronchiectasis to help improve their care and treatment.

  Recruiting at 9 sites China-Japan Friendship Hospital · Beijing, Beijing Municipality and 8 other locations · NCT06798077

• Vitamin D treatment for patients with bronchiectasis

  This study is testing if vitamin D supplements can help people with bronchiectasis who have low vitamin D levels experience fewer flare-ups.

  Recruiting Phase 4 Queen Mary Hospital, Hong Kong · Hong Kong · NCT06551337

• Using breath analysis to identify multiple lung diseases

  This study is testing if analyzing breath samples can help identify different lung diseases like lung cancer and COPD in a large group of 10,000 people.

  Recruiting ChromX Health · Guangzhou, Guangdong · NCT06528418

• Using smartphone technology to evaluate airway conditions

  This study is testing if smartphone technology can help check lung health and spot breathing problems in both healthy people and those with asthma or COPD.

  Recruiting at 2 sites Indiana University · Indianapolis, Indiana and 1 other locations · NCT06512064

• Comparing two antibiotic treatments for early lung infections in adults with bronchiectasis

  This study is testing which of two antibiotic treatments works better for adults with bronchiectasis who have early lung infections caused by Pseudomonas aeruginosa.

  Recruiting at 16 sites Phase 2 Centre Hospitalier Intercommunal Creteil · Amiens and 17 other locations · NCT06368804

• CT biomarkers for classifying and predicting bronchiectasis outcomes

  This project will test whether features seen on chest CT scans can help classify bronchiectasis and predict how adults with bronchiectasis will do over time.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06346938

• Disease progression and nutritional status in bronchiectasis

  The study will see if detailed nutritional measures (BMI, arm and calf circumference, skinfold thickness, and grip strength) relate to disease progression in adults with non-cystic fibrosis bronchiectasis.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei and 1 other locations · NCT06344000

• SELF-BREATHE: a self-guided online program to reduce chronic breathlessness in adults

  This study will test whether SELF-BREATHE, a self-guided internet-based support program, can help adults with chronic breathlessness from lung or heart conditions breathe easier and feel less distressed.

  Recruiting King's College Hospital NHS Trust · London · NCT06326957

• Using hypertonic saline to improve mucus clearance in bronchiectasis

  This study is testing if a special salt solution delivered through a nebulizer can help adults with bronchiectasis clear mucus from their lungs better.

  Recruiting Phase 4 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06242795

• Comparing Itraconazole with Standard Care for Chronic Aspergillus Infection in Bronchiectasis

  This study is testing if adding the antifungal medication itraconazole to standard care can help adults with bronchiectasis and chronic Aspergillus infection have fewer flare-ups.

  Recruiting Phase 3 Post Graduate Institute of Medical Education and Research, Chandigarh · Chandigarh, Chandigarh · NCT06160713

• Creating a database for patients with bronchiectasis and NTM in Canada

  This study is creating a database to gather information from adults with bronchiectasis and NTM to help improve care and understanding of these conditions.

  Recruiting University of Calgary · Calgary, Alberta · NCT06144996

• Examining the impact of cardiovascular issues on bronchiectasis patients

  This study looks at how heart problems affect the health and quality of life of people with bronchiectasis during flare-ups compared to those without heart issues.

  Recruiting Assiut University · Asyut · NCT05783869

• Using high-flow nasal cannula for managing bronchiectasis exacerbations

  This study is testing if using a high-flow nasal cannula can help people with bronchiectasis who have breathing problems during flare-ups feel better compared to traditional breathing support methods.

  Recruiting Assiut University · Asyut · NCT05741697

• Research on factors affecting bronchiectasis progression

  This study looks at how different factors, like bacteria in the lungs, affect the worsening of bronchiectasis in people with this chronic lung condition.

  Recruiting at 3 sites Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Guiyang, Guizhou and 2 other locations · NCT05731427

• Long-term oral Staphylococcus albicans tablets for bronchiectasis

  This study is testing if taking Staphylococcus albicans tablets for a long time can help people with bronchiectasis have fewer flare-ups and improve their overall well-being.

  Recruiting Qianfoshan Hospital · Jinan, Shandong · NCT05407792

• Thermotherapy for persistent bacterial lung infections

  This study is testing if regular heat therapy can help people with chronic lung infections get rid of stubborn bacteria that don’t respond to regular antibiotics.

  Recruiting Chronic Obstructive Pulmonary Disease Trial Network, Denmark · Hellerup, Capital Region · NCT05351242

• Microbial colonization and evolution in the lower airways of people with bronchiectasis

  This project will test whether monthly sputum microbiome profiling and Pseudomonas genome sequencing over three years can track how bacteria colonize and change in people with bronchiectasis.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT04966793

• Comparing home-based and hospital-based pulmonary rehabilitation for bronchiectasis

  This study is testing whether doing pulmonary rehabilitation at home or in the hospital is better for people with bronchiectasis to see which helps them breathe easier and feel better.

  Recruiting Istanbul Medipol University Hospital · Istanbul, Zeytinburnu · NCT03561818

• Registry of healthy controls for respiratory diseases

  This study is collecting health information from healthy volunteers to help researchers better understand respiratory diseases like asthma and COPD by comparing it to data from patients with these conditions.

  Recruiting Seoul National University Hospital · Seoul, Seoul · NCT03120481

• Evaluating the lung microbiome in patients with NTM bronchiectasis

  This study is trying to see how changes in the lung bacteria of people with non-tuberculous mycobacterial disease might be linked to their condition.

  Recruiting NYU Langone Health · New York, New York · NCT02779478

• Registry for patients with chronic airway diseases

  This study is gathering information from people with chronic airway diseases like COPD and asthma to better understand their conditions and find ways to improve their care.

  Recruiting at 2 sites Seoul National University Hospital · Seongnam-si, Gyeonggi-do and 2 other locations · NCT02527486

• Understanding the natural history of bronchiectasis

  This study looks at how bronchiectasis develops over time in people with chronic lung infections, especially focusing on genetic and immune factors that might make them more prone to these infections.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT00943514

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• A unifying mucus-driven paradigm for bronchiectasis in adults

  A researchers-led program aims to better understand why bronchiectasis causes chronic cough and lung problems in adults and to explore new ways to treat it.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11442862

• Bronchiectasis and COPD in Smokers: AI CT Tools and Proteomics to Predict Progression

  This project uses AI-powered CT imaging and proteomics to understand how bronchiectasis progresses in adults who smoke and have COPD, with the goal of identifying who is at higher risk for worsening lung disease.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11296938

• Nebulized NO-releasing therapy for Pseudomonas infections in bronchiectasis

  A new inhaled nitric oxide–releasing treatment is being tested to help people with bronchiectasis who have lung infections from Pseudomonas bacteria.

  NIH research Vast Therapeutics, INC. · Morrisville, UNITED STATES · NIH-11250047

• Understanding how bronchiectasis progresses in smokers

  This study is looking at how bronchiectasis gets worse over time in people who smoke, using smart imaging technology to find signs that could help predict changes in their lung health, with the goal of improving care for those dealing with this condition and COPD.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11086752

• Using a new treatment to fight lung infections caused by Pseudomonas aeruginosa in patients with bronchiectasis

  This study is testing a new inhalable treatment for people with bronchiectasis who have tough lung infections caused by Pseudomonas aeruginosa, aiming to help them breathe better and reduce infections.

  NIH research Vast Therapeutics, INC. · Morrisville, UNITED STATES · NIH-11065101

Related topics

Quick answers

How many Bronchiectasis clinical trials are recruiting right now?

44, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 43 countries. The most sites are in China (12 trials), United States (7 trials), United Kingdom (6 trials), Egypt (6 trials), Turkey (Türkiye) (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 5, Phase 3: 2, Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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