Using smartphone technology to evaluate airway conditions
Official title: Advancing Telemedicine in Pulmonology: Acoustic-waveform Respiratory Evaluation (AWARE) Via Sensing and Machine Learning on Smartphones
Run by Indiana University · NCT06512064 · Data updated 2026-11-12
This study is testing if smartphone technology can help check lung health and spot breathing problems in both healthy people and those with asthma or COPD.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 8 Years to 70 Years |
| Sex | All |
| Enrollment | 800 (estimated) |
| Sponsor | Indiana University Academic / other |
| Locations | 2 sites (Indianapolis, Indiana and 1 other locations) |
| Status | Recruiting |
| Started | July 23, 2024 |
| Main results expected | April 2029 |
| Study ends | April 2029 |
| Registry record updated | October 5, 2026 |
| Trial ID | NCT06512064 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals aged 8-65 with asthma, COPD, cystic fibrosis, or other airway diseases, as well as healthy controls.
✕Probably not a fit
Patients with acute or chronic illnesses that may affect lung function or those unable to perform the required tests may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to assess the feasibility of utilizing smartphone speakers and microphones to evaluate airway caliber, detect obstructions, and aid in diagnosing airway diseases such as asthma and COPD. By employing machine learning techniques, the study seeks to enhance pulmonary telemedicine, allowing for more accurate and reliable monitoring of lung function and disease exacerbations. Participants will include both healthy individuals and those diagnosed with various airway diseases, enabling a comprehensive evaluation of the smartphone-based approach. The study will focus on developing a method that can classify disease groups and estimate lung function adaptively.
Why it matters
Potential benefit: If successful, this approach could significantly improve remote monitoring and management of respiratory diseases, enhancing patient outcomes and quality of life.
How similar studies have gone: While the use of smartphone technology in healthcare is growing, this specific approach to pulmonary disease evaluation is novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age 8-70 years (to ensure ability to perform other PFTs; up to 75 years for COPD subjects in the UPMC adult clinic only). 2. Ability to perform spirometry and oscillometry 3. Signed informed consent (and assent for children as appropriate) 4. No respiratory or other major disease (for healthy controls), or physician-diagnosed asthma, COPD, CF, or other airway diseases Exclusion Criteria: 1. Inability or unwillingness to perform AWARE, spirometry, or oscillometry 2. Acute or chronic illness that, at the judgement of investigators, may affect lung function and alter the results of AWARE or the reference PFTs (spirometry and AOS)
Where it's running
-
Indiana University
Indianapolis, Indiana, United States Recruiting -
University of Pittsburgh
Pittsburgh, Pennsylvania, United States Recruiting
Study contacts
- Principal investigator: Erick Forno, MD MPH — Indiana University
- Study coordinator: Elizabeth Rizzi, RN
- Email: lizbuell@iu.edu
- Phone: 317-626-6937
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.