Using smartphone technology to evaluate airway conditions

Advancing Telemedicine in Pulmonology: Acoustic-waveform Respiratory Evaluation (AWARE) Via Sensing and Machine Learning on Smartphones

Not applicable Interventional Indiana University · NCT06512064

This study is testing if smartphone technology can help check lung health and spot breathing problems in both healthy people and those with asthma or COPD.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment800 (estimated)
Ages8 Years to 70 Years
SexAll
SponsorIndiana University Academic / other
Locations2 sites (Indianapolis, Indiana and 1 other locations)
Trial IDNCT06512064 on ClinicalTrials.gov

What this trial studies

This study aims to assess the feasibility of utilizing smartphone speakers and microphones to evaluate airway caliber, detect obstructions, and aid in diagnosing airway diseases such as asthma and COPD. By employing machine learning techniques, the study seeks to enhance pulmonary telemedicine, allowing for more accurate and reliable monitoring of lung function and disease exacerbations. Participants will include both healthy individuals and those diagnosed with various airway diseases, enabling a comprehensive evaluation of the smartphone-based approach. The study will focus on developing a method that can classify disease groups and estimate lung function adaptively.

Who should consider this trial

Good fit: Ideal candidates include individuals aged 8-65 with asthma, COPD, cystic fibrosis, or other airway diseases, as well as healthy controls.

Not a fit: Patients with acute or chronic illnesses that may affect lung function or those unable to perform the required tests may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve remote monitoring and management of respiratory diseases, enhancing patient outcomes and quality of life.

How similar studies have performed: While the use of smartphone technology in healthcare is growing, this specific approach to pulmonary disease evaluation is novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age 8-70 years
2. Ability to perform spirometry and oscillometry
3. Signed informed consent (and assent for children as appropriate)
4. No respiratory or other major disease (for healthy controls), or physician-diagnosed asthma, COPD, CF, or other airway diseases

Exclusion Criteria:

1. Inability or unwillingness to perform AWARE, spirometry, or oscillometry
2. Acute or chronic illness that, at the judgement of investigators, may affect lung function and alter the results of AWARE or the reference PFTs (spirometry and AOS)

Where this trial is running

Indianapolis, Indiana and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AsthmaCOPDCystic FibrosisCiliary Motility DisordersBronchiectasisAirway MalaciaHealthy Control
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.