Vitamin D treatment for patients with bronchiectasis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of vitamin D replacement on reducing the occurrence of bronchiectasis exacerbations in patients with vitamin D deficiency. It is a self-controlled pilot study that invites participants from a previous related study to assess the impact of vitamin D3 supplementation. Participants will have their blood levels of 25-hydroxyvitamin D monitored throughout the study. The aim is to provide insights into the potential benefits of vitamin D in managing bronchiectasis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. ages 18 years or above, male or female.
2. confirmed diagnosis of non-CF bronchiectasis based on high-resolution computed tomography (HRCT) scan.
3. participation in the prior study entitled "Prospective clinical study on serum 25-hydroxyvitamin D (25-OH D) level and risk of bronchiectasis exacerbation" (UW 22-317)

Exclusion Criteria:

1. underlying asthma, COPD and other co-existing respiratory diseases
2. underlying osteoporosis
3. supplementary Vitamin D in their regimen
4. advanced chronic kidney disease with estimated glomerular filtration rate (eGFR) \< 30mL/min

Where it's running

• Queen Mary Hospital
  Hong Kong, Hong Kong Recruiting

Study contacts

• Study coordinator: Wang Chun Kwok, MBBS
• Email: kwokwch@hku.hk
• Phone: 2255 3111

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.