Understanding how bronchiectasis progresses in smokers
Clinical implications and Proteomics of Bronchiectasis Progression in Smokers
['FUNDING_R01'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-11086752
This study is looking at how bronchiectasis gets worse over time in people who smoke, using smart imaging technology to find signs that could help predict changes in their lung health, with the goal of improving care for those dealing with this condition and COPD.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11086752 on ClinicalTrials.gov |
What this research studies
This research investigates the progression of bronchiectasis, a condition characterized by the abnormal widening of airways, particularly in individuals who smoke. Using advanced artificial intelligence-based imaging techniques, the study aims to objectively measure changes in bronchiectasis over time in smokers. By analyzing data from two large cohorts, the research seeks to identify biomarkers that could predict the progression of this condition and its impact on lung health. This approach may lead to improved clinical care for patients suffering from both bronchiectasis and chronic obstructive pulmonary disease (COPD).
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 65 and older who have a history of smoking and may be experiencing bronchiectasis or COPD.
Not a fit: Patients who do not smoke and are under 65 years of age may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring and treatment strategies for patients with bronchiectasis, particularly those who smoke.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to study lung conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DIAZ, ALEJANDRO — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: DIAZ, ALEJANDRO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.