Understanding the impact of multimorbidity on chronic airway diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Chronic Airway Disease and Multimorbidity (CAM) Cohort is a nationwide, prospective, multicenter observational study that aims to recruit at least 2,000 patients hospitalized for exacerbations of chronic obstructive pulmonary disease (COPD), asthma, or bronchiectasis. The study will collect comprehensive data on demographics, medical history, comorbidities, lung function, and quality of life during hospitalization and follow up with participants for one year post-discharge. By analyzing how multimorbidity affects treatment outcomes and healthcare utilization, the study seeks to provide insights into the management of chronic airway diseases.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with chronic obstructive pulmonary disease ≥40 years of age; patients with asthma and bronchiectasis ≥18 years of age;
* The primary diagnosis on admission was "acute exacerbation of chronic obstructive pulmonary disease, uncontrolled asthma, or acute exacerbation of bronchiectasis".

Exclusion Criteria:

* Patients were unable to undergo spirometry during the stabilization period;
* Expected survival is less than 1 month;
* Refusal to sign an informed consent form;
* Chest imaging showed emerging patchy infiltrating shadows, lobar or segmental solid shadows, ground glass shadows, or interstitial changes with or without pleural effusion;
* Patients with cystic fibrosis or with interstitial lung disease or other lung diseases with tractional branchial dilatation.

Where it's running

• National Center for Respiratory Medicine, China-Japan Friendship Hospital
  Beijing, Beijing Municipality, China Recruiting
• Zhujiang Hospital of Southern Medical University
  Guangzhou, Guangdong, China Recruiting
• Henan Provincial People's Hospital
  Zhengzhou, Henan, China Recruiting
• Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
  Wuhan, Hubei, China Recruiting
• The Second Xiangya Hospital of Central South University
  Changsha, Hunan, China Recruiting
• The First Affiliated Hospital of China Medical University
  Shenyang, Liaoning, China Recruiting

Study contacts

• Principal investigator: Ting Yang, MD — China-Japan Friendship Hospital, National Center for Respiratory Medicine
• Study coordinator: Ke Huang, MD.
• Email: huangke_zryy@163.com
• Phone: +8615120079197

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.