Sponsor or institution
Clinical trials and research at University of Arizona
As of November 12, 2026, Find a Trial lists 58 clinical trials run by University of Arizona that are recruiting, in United States. 1 was first registered in the last 30 days. By phase: Phase 2 (6), Early Phase 1 (4), Phase 1/2 (3), Phase 3 (2). There are also 725 NIH-funded research projects at this institution, with $464.2 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 58Clinical trials
- 725NIH research projects
- 1New in 30 days
- 1Country
Newest trials
All recruiting trials (58)
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Diagnosing malignant pleural effusion with the EPISEEK-MPE liquid biopsy
A test called EPISEEK-MPE is being checked to see if it can tell cancer from non-cancer pleural effusions using fluid already removed for care.
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Linking social care with healthcare to help manage chronic diseases
This trial tests whether pairing patients with trained community health workers can help them get transportation, healthy food, information, and better access to care to improve health in conditions like hypertension, diabetes, and high cholesterol.
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Apixaban vs Warfarin for a Left Ventricular Thrombus
This study tests whether apixaban can more conveniently and safely dissolve a left ventricular blood clot compared with warfarin.
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Breathing for Two: Can inspiratory muscle training help with blood pressure in late pregnancy?
This study tests whether a home-based inspiratory muscle strength training program can safely lower blood pressure in pregnant people in their third trimester.
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Comparative test of PAP therapy, a dental device, and atomoxetine-oxybutynin for adults with obstructive sleep apnea
This study tests three options for obstructive sleep apnea to see which works best and is easiest for patients to use.
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GLP-1 RA plus standard treatment in first-line metastatic GI cancers
This early-phase trial tests whether adding a GLP-1 receptor agonist to standard first-line chemotherapy is safe and feasible for people with metastatic pancreatic, colorectal, or liver cancer.
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Vaginal DHEA vs Vaginal Estrogen for Menopause Symptoms
This study tests whether vaginal DHEA or vaginal estrogen helps with vaginal dryness, discomfort, and urinary symptoms in peri- or post-menopausal women by randomly assigning participants to one treatment and measuring their symptoms over time.
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Social support for long-term lung cancer survivors
This study tests whether a CBT-based social support program helps long-term lung cancer survivors feel more socially connected and have better quality of life, using mobile-phone based checks of daily interactions.
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Breathwork for older adults after knee replacement
This study tests whether a quick, at-home breathwork activity can help adults 65 and older recover better after knee replacement surgery.
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Mind After Midnight — how being awake between 2:00 and 4:00 AM affects mood and decision-making
This project will test whether being awake during the biological night (2:00–4:00 AM) increases negative mood, poor decision-making, and suicidal thoughts in adults who have had suicidal ideation in the past six months.
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Symptom Management and Survivorship Coaching for Advanced Cancer Patients and Caregivers
This study tests a 10-week Symptom Management and Survivorship Handbook plus telephone coaching to help metastatic cancer patients and their caregivers manage symptoms and stay connected.
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Sodium thiosulfate to protect hearing during cisplatin therapy in adults with solid tumors
This study tests Pedmark sodium thiosulfate to see if it reduces hearing loss in adults receiving standard cisplatin chemotherapy.
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Circadian Light Exposure Adjustment for Restfulness in Young Children
This study tests three ways to reduce evening light for 5- to 6-year-olds with sleep-onset difficulties to see if it helps them fall asleep sooner.
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Olorofim for Early Coccidioidal Meningitis
This study tests olorofim in adults with early coccidioidal meningitis to see if it helps manage the infection before it worsens.
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Whole-mushroom psilocybin for obsessive-compulsive disorder.
This trial tests whether different doses of whole psilocybin mushroom in chocolate can help adults with moderate-to-severe OCD who are not taking other psychoactive medications or street drugs.
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Nationwide sleep extension program for adults who sleep too little
This program will try a personalized, Fitbit-supported sleep-extension approach to see if adults who usually sleep 6 hours or less can get more nightly sleep and improve related outcomes.
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Home-based brain stimulation plus online chair yoga for chronic knee pain in people with Alzheimer's disease
This project will test whether combining home-based low-intensity brain stimulation (tDCS) with online chair yoga can reduce chronic knee pain in older adults with Alzheimer's disease and related dementias.
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Corazones Unidos: Heart health program for Mexican-origin adults
This program tests whether a community health worker-led education and support program can increase heart disease risk awareness and encourage healthy lifestyle changes for Mexican-origin adults with MASLD in Southern Arizona.
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Using movies and shows with ThinkHumanTV to improve mental resilience
This project tests whether adding ThinkHumanTV lessons to six weekly 90-minute group viewings of Netflix or Disney movies/shows helps adults in long-term community mental health care feel more resilient and improve their well-being.
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Endotype-directed treatment for obstructive sleep apnea in people with Down syndrome
This project will test whether a precision approach—using atomoxetine plus oxybutynin for some people and oxygen for others based on breathing patterns—works better than giving atomoxetine-plus-oxybutynin to everyone with Down syndrome and obstructive sleep apnea.
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Prophylactic DLI-X to Prevent Leukemia Relapse After Transplant
This first-in-human trial tests a prophylactic DLI-X approach to see if it can prevent relapse after matched sibling or haploidentical stem cell transplant in patients with acute leukemias and related blood disorders.
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3D-printed versus conventional hearing-aid ear tips for comfort and fit
This study will test whether 3D-printed hearing-aid ear tips are as comfortable, fit as well, and sound as good as standard ear tips for people with bilateral sensorineural hearing loss, and will compare how long each takes to make and how much each costs.
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3D-printed versus standard hearing-aid ear tips for comfort, fit, and sound
This study will test whether 3D-printed hearing-aid ear tips work as well as or better than standard ear tips for adults with normal hearing.
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Exercise and the tumor microenvironment in non-small cell lung cancer
This project will test whether a pre-surgery exercise program changes the tumor microenvironment and improves peri-operative outcomes for people with early-stage non-small cell lung cancer.
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Same-day colectomy safety for selected patients undergoing robotic colorectal surgery.
This project tests whether adults having robotic-assisted right colectomy, sigmoidectomy, or low anterior resection can safely go home the same day after surgery.
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Patient-reported outcomes after pancreatic surgery
This project will see how pancreatic surgery affects quality of life and whether adults who have pancreatic resection feel satisfied with their decision over time.
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Omega-3 supplements to address diet-driven health disparities
This test will see if daily omega-3 supplements lower inflammation and improve heart-related blood markers in healthy non-Hispanic Black and White adults with different FADS gene types.
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Comparing bone graft options for ACL reconstruction
This study tests which type of bone graft, either a patient's own bone or a special putty, works better for people getting surgery to fix a torn ACL.
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ILAM-guided VT ablation for sustained VT in adults with heart disease
This trial tests whether using Isochronal Late Activation Mapping to guide VT ablation works as well as the standard voltage-based approach in adults with sustained monomorphic VT.
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Optimizing pulse (beans, lentils, peas) intake for cardiometabolic health
We will test whether eating 1.5 or 3 cups of pulses each week helps adults who currently eat less than 1.5 cups/week improve cholesterol, inflammation, blood sugar, and blood pressure.
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Personalized exercise program for patients on hemodialysis
This study is testing whether a personalized exercise program can help people on hemodialysis feel better and improve their quality of life compared to a standard exercise plan.
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Radiation plus tarlatamab for DLL3-expressing tumors
This trial will test whether giving tarlatamab together with standard palliative or consolidative radiation is safe for adults with DLL3-expressing or DLL3-prevalent tumors such as melanoma, medullary thyroid cancer, sinonasal undifferentiated carcinoma, esthesioneuroblastoma, and bladder cancer.
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Improving environmental health literacy through tailored data reporting
This study is trying out different ways to present environmental health information to see which designs help people from various communities understand it better.
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Improving daily routines to help youth with ADHD
This study is testing if changing daily or nightly routines can help improve focus and sleep for teenagers with ADHD.
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Nutrition and exercise prehabilitation to reduce inflammation in American Indian adults with cancer
This program will test whether a 3-week nutrition and exercise prehabilitation plan can lower inflammation markers in American Indian adults with cancer who are waiting to start treatment.
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Using exercise to enhance immune cell therapy for blood cancer
This study tests if a short cycling exercise can improve immune cells from healthy donors to help treat blood cancers like leukemia and lymphoma more effectively.
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Using Transcranial Magnetic Stimulation to Improve Sleep Quality
This study is testing if a new treatment using magnetic stimulation can help people with insomnia sleep better.
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4-Aminopyridine to help heal second-degree skin burns
This trial will try 4-aminopyridine in adults with recent second-degree burns to see if it speeds healing.
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Methadone Patient Access to Collaborative Treatment
This trial tests a program called MPACT to see if it helps people stay in methadone treatment and reduces overdoses, while also examining how staff and patient stress affect implementation.
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4-aminopyridine for faster skin wound healing
This trial will see if 4-aminopyridine helps small skin wounds heal faster in healthy adults aged 18–70.
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Using a smartphone app to help older adults with mild cognitive impairment take their blood pressure medications
This study is testing whether a smartphone app that sends medication reminders can help older adults with mild cognitive impairment take their blood pressure medications more regularly.
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Testing Angiotensin (1-7) for treating moderate to severe traumatic brain injury
This study is testing if a new drug called Angiotensin (1-7) can help people with moderate to severe traumatic brain injuries recover better over 21 days.
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Device for treating carpal tunnel syndrome
This study tests a new device that gently pushes on the wrist while you sleep to see if it helps people with carpal tunnel syndrome feel better compared to using a regular wrist brace.
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Examining skin changes from sun exposure in people with and without skin cancer
This study is testing how sun exposure affects skin proteins and genes in people aged 40 and older, comparing those with and without a history of skin cancer to see what differences might influence cancer risk.
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Using 18F-Fluciclovine PET/CT to Identify Brain Metastasis
This study is testing if a special type of PET scan can help doctors find brain metastases more accurately in patients who have unclear MRI results.
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Evaluating 4-aminopyridine for nerve injury diagnosis
This study is testing if a single dose of 4-aminopyridine can help doctors better diagnose the severity of nerve injuries in people.
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Comparing word learning in late talking toddlers using familiar and unfamiliar words
This study is testing whether teaching late talking toddlers familiar words like animals helps them learn better than teaching them unfamiliar words.
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Online compassion training for breast cancer survivors and their caregivers
This study is testing if an online compassion training program can help reduce depression and anxiety in breast cancer survivors and their caregivers when they do it together compared to doing it alone or just receiving health education.
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Morning light exposure to improve mood in military personnel
This study is testing if daily morning light therapy can help improve mood and reduce suicidal thoughts in military personnel.
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Personalized caffeine dosing for better performance during sleep deprivation
This study is testing if a personalized caffeine plan can help people perform better and feel less tired after not getting enough sleep.
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Improving language skills in people with aphasia
This study is testing a new language treatment for people with aphasia to see if it helps them improve their speaking and understanding skills.
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Using brain stimulation to improve sleep in people with insomnia
This study is testing if a brain stimulation technique can help people with insomnia sleep better by calming down a part of the brain that may be overactive.
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Improving language function in patients with Primary Progressive Aphasia
This study is testing whether a new treatment that combines brain stimulation with language therapy can help people with Primary Progressive Aphasia improve their language skills.
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Personalized wellness intervention for smoking cessation in adults living with HIV
This study tests a personalized program to help adults with HIV quit smoking and see if it works better than standard methods.
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Evaluating the effects of two drugs on heart function in patients with advanced pulmonary arterial hypertension
This study is testing if a combination of two heart medications can improve heart function more than just one medication in people with advanced pulmonary arterial hypertension.
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High-resolution, lower-dose dedicated breast CT
This study will test whether a new dedicated breast CT scan gives clearer 3-D breast images at a lower radiation dose for women age 40 and older who are having screening, diagnostic imaging, or a biopsy.
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Using 4-aminopyridine to improve recovery from nerve injury after prostate surgery
This study is testing if a medication called 4-aminopyridine can help men recover better from nerve injuries after prostate surgery, possibly reducing issues like erectile dysfunction and urinary incontinence.
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Biospecimen collection for cancer research
This study is collecting and storing samples from patients with pancreatic cancer to help researchers learn more about the disease and improve future treatments.
NIH-funded research (newest 40 of 725)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Retinal signals in early diabetes and how they affect vision
This grant looks at how diabetes changes the signals in the retina that control vision, with a focus on inner retinal cells and how these changes may lead to vision problems.
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Mining safety training that connects research to practice for Western miners
A patient-facing overview of a U.S. mining safety program that partners universities and mining operators to improve training, safety practices, and outcomes for mine workers in the Western United States.
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Developing small molecules to treat TDP-43 related brain diseases
A potential new drug candidate (XL20) for diseases like Alzheimer’s and other dementias linked to TDP-43 protein problems is being developed and refined for people who live with these conditions.
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Mobile platform using AI to screen for oral cancer in low-resource communities
A low-cost, AI-powered mobile tool helps frontline healthcare workers screen for oral cancer and triage patients in communities with limited access to specialists.
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A new optical method to image skin cancers using synthetic waves
A small grant is funding the development and testing of tissue-mimicking skin phantoms to improve non-invasive imaging of skin cancers.
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MRI-guided precision care for infants with cleft palate
We’re exploring how MRI can help tailor early care for babies with cleft palate to support better speech outcomes.
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How our genes and immune system affect C. difficile infections
This project looks at how a common human gene variant and immune factors influence the severity of C. difficile infections and whether targeting inflammation could help patients.
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How Brain Connectivity Changes Relate to Aging and Memory
A study aims to understand how aging affects brain connections and how these changes relate to memory and thinking in older adults.
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Ionic liquids to improve oral delivery and effectiveness of oxfendazole
This project tests a new way to give an existing worm‑fighting drug (oxfendazole) by using special liquids to help it work better in the body, potentially helping people with cryptococcal meningitis.
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Diabetic Foot Ulcer Healing Network at the University of Arizona
A NIH-supported project at the University of Arizona aims to improve healing of diabetic foot ulcers by studying biomarkers and running high-quality clinical trials.
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How bacteria respond to copper toxicity in the body
A study to understand how pathogenic bacteria manage copper stress inside the human host, which could reveal new ways to support infections fighting back.
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Amish farm air and cow barn substances protecting kids’ lungs from RV and asthma
A study to understand how natural substances from traditional Amish farm environments may help prevent asthma in children by protecting their lungs from rhinovirus infections.
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Skeletal MyBP-C Regulation and Structure in Arthrogryposis
A new project at the University of Arizona looks at how a muscle protein called MyBP-C controls muscle contraction and how its changes might cause arthrogryposis, with the goal of guiding future treatments.
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Dual targeting of heart cell receptors to prevent chemotherapy heart damage
Atrial patients receiving the chemotherapy drug doxorubicin may be protected from heart damage by targeting two heart cell receptors at once.
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Fibroblast Growth Factor 1 to Reduce High Lipids and Plaque in Adults with Diabetes
A new approach uses a modified FGF1 protein to lower bad cholesterol and prevent artery plaque buildup in adults with Type 2 diabetes, aiming for safer and more effective treatment.
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Understanding brain circuits to help develop better mental health therapies
Researchers are testing how well brain circuits involved in emotion and thinking work in animals to guide new treatments for mental health challenges.
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All of Us pediatric participation and engagement expansion
A national effort to enroll more children and families in a diverse health study so they can help researchers tailor care to kids.
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CC16 in childhood and resilience to early airflow limitation in adult life
A long-term study looks at whether a lung-protective protein called CC16 in children helps prevent early breathing problems that can lead to COPD in adulthood.
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CC16 and resilience to early airflow limitation from childhood to adulthood
A study looking at how a protein in the lungs (CC16) might protect children with early lung issues from developing airway problems later in life.
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CC16 and resilience to early lung problems into adulthood
A study from the University of Arizona looks at whether a small lung protein called CC16 helps protect children with early signs of breathing problems from developing COPD-related issues later in life.
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CC16 in childhood and resilience to early airflow limitation in adulthood
This grant explores how a protein called CC16 in childhood may protect against early lung problems that can lead to COPD later in life.
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CC16 in childhood and resilience to early airflow limitation in adult life
A study to understand how a protein called CC16 may protect children with early airway issues from developing breathing problems later in life.
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Learning how BEST4+ gut cells form and help the intestine
This project looks at how a special gut cell called BEST4+ develops and whether losing these cells plays a role in inflammatory bowel disease.
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PARP1 and PARylation: new keys to gut inflammation
A nearby-to-patient look at how a cellular tag called PARylation, driven by PARP1, may influence gut inflammation in inflammatory bowel disease.
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Role of SMAD1/5/8 signaling in liver fibrosis
This grant explores how specific liver cell signals influence scarring (fibrosis) in the liver, with a focus on people who have alcohol-related liver disease or related conditions.
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Community-Based Approach to Boost Vaccines for All Ages in Border and Rural Areas
A community-driven project will place an immunization specialist in rural dental clinics to improve vaccine access and acceptance for people of different ages in border and rural regions.
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Economic analysis of the MEW self-management program for epilepsy (MINDSET) in real-world settings
This grant studies how a proven epilepsy self-management program can be implemented in communities and clinics, and how its costs and benefits stack up.
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Host evolution after disease outbreaks in birds
Researchers study how wild bird populations respond evolutionarily when new diseases jump into their communities, using the Galapagos as a natural laboratory.
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Genomic and epigenomic roadmap to understand otosclerosis
This NIH grant aims to map the genetic and epigenetic factors behind otosclerosis to better understand why this bone disease causes hearing loss.
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Non-invasive, microscopic biomarkers to detect CIPN in chemotherapy patients
This grant aims to develop a non-invasive imaging method to measure nerve changes in patients undergoing chemotherapy to better understand and monitor chemotherapy-induced peripheral neuropathy (CIPN).
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Selective autophagy and aging in Alzheimer’s disease: a small-molecule approach
A patient-facing grant exploring how boosting the cell’s recycling system might protect brain cells in Alzheimer-related illness through a targeted drug approach.
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GATA4's role in why some hearts are born with two valve cusps
A study in mice and human genetics will look at how a specific GATA4 gene change leads to bicuspid aortic valve and related heart problems.
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Genetic clues to how blood flow in arteries increases or lowers heart disease risk
Researchers are studying how natural human genetic differences affect how arteries respond to blood flow, which may help explain why some people develop vascular disease beyond cholesterol levels.
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Duerme Mejor: A Sleep Health Program for Mexican Americans at the US-Mexico Border
A community-based program to help Mexican American adults sleep better through a culturally tailored, multimodal approach.
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Enteric glial cell reprogramming and MENIN loss in dpNETs
A study to understand how losing a gene called MENIN in gut-supporting glial cells might turn them into neuroendocrine tumor cells in people with MEN1.
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Neuroendocrine links to female COPCs and endometriosis-related pain
This NIH grant explores how stress-related hormones, especially prolactin, may drive pelvic and migraine pain in women with endometriosis and related chronic pain conditions.
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Improving blood vessel repair after pediatric ARDS
Aims to better repair the lungs of children who have ARDS by delivering targeted therapy to lung blood vessels using tiny nanoparticles.
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Culinary nutrition program for prostate cancer patients and family caregivers
A dyadic cooking program helps men with prostate cancer and their caregivers eat more fruits and vegetables to support health and quality of life.
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PNA5 for VCID and Alzheimer's Dementias: A first-in-human safety study
A first-in-human trial tests a new drug, PNA5, to see if it is safe and tolerable for adults with vascular cognitive impairment and Alzheimer's-related dementias.
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HPV-related head and neck and cervical cancers: finding key gene networks and lncRNA markers for targeted therapy
Researchers will study how HPV-related cervical and head-and-neck cancers differ at the gene and RNA level to uncover potential targets for precision treatment.
Quick answers
How many clinical trials run by University of Arizona are recruiting right now?
58, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 6, Early Phase 1: 4, Phase 1/2: 3, Phase 3: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.