Diagnosing malignant pleural effusion with the EPISEEK-MPE liquid biopsy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multi-site validation study evaluates the EPISEEK-MPE liquid biopsy assay as a diagnostic aid for malignant pleural effusions. Researchers compare the test’s results with standard clinical information and patient records to determine reliability across age, race, gender, and ethnicity. The study uses excess pleural fluid from routine drainage and collects medical-record data to assess diagnostic performance and potential survival associations. It aims to establish the EPISEEK-MPE test as a complementary tool to cytology in differentiating malignant from benign effusions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients having pleural fluid drained for clinical care (thoracentesis or chest tube placement)
* Consent to have pleural fluid sample used for research

Exclusion Criteria:

\- Insufficient fluid available following clinical drainage procedure

Where it's running

• Banner University Medical Center South
  Tucson, Arizona, United States Recruiting
• Banner University Medical Center Tucson
  Tucson, Arizona, United States Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.