CC16 in childhood and resilience to early airflow limitation in adulthood
Official title: CC16 in childhood and resilience to early airflow limitation in adult life
Funded at University of Arizona · NIH-11511724 · Data updated 2026-11-12
This grant explores how a protein called CC16 in childhood may protect against early lung problems that can lead to COPD later in life.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | September 25, 2017 |
| Project end | March 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $9,148 |
| NIH project number | 3R01AI135108-07S2 |
| Project ID | NIH-11511724 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and adults who are at risk for reduced lung growth or COPD development, or who have a history of early-life airway issues.
✕Less likely to help
Individuals without any history or risk of early lung function impairment may not directly benefit from this research.
What this research studies
Researchers are looking at how CC16, a protective protein in the airways, might guard against early lung changes that set the stage for COPD. The project follows people from childhood into adulthood to understand who stays healthier and why. By studying measuring CC16 levels and lung function, the team hopes to identify factors that confer resilience to poor lung growth. The work could point to new ways to prevent COPD by supporting lung health from an early age.
Why it matters
Potential benefit: If successful, findings could help prevent COPD by identifying individuals at risk early and guiding interventions to boost airway protection.
How similar studies have gone: Previous work suggests CC16 may have protective anti-inflammatory effects, but the specific role in resilience to early airway limitation is still being explored.
Where this research is happening
-
University of Arizona
Tucson, United States Active
Researchers
- Principal investigator: Guerra, Stefano — University of Arizona
- Study coordinator: Guerra, Stefano
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.