Corazones Unidos: Heart health program for Mexican-origin adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a community-based, community health worker (CHW)-led intervention focused on Mexican-origin adults diagnosed with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). Participants with a confirmed MASLD diagnosis (CAP ≥ 248 dB/m) will be paired with CHWs who provide education, risk communication, and support to promote lifestyle changes, and participants may enroll with an adult member of their social network. The primary aims are to determine the acceptability and feasibility of the intervention and its ability to increase cardiovascular risk awareness and uptake of healthier behaviors. Activities will be delivered in English or Spanish at the University of Arizona Collaboratory for Metabolic Disease Prevention & Treatment in Tucson, with outcome measures focused on engagement, self-reported behavior change, and implementation practicality.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Eligible intervention participants must (1) be Mexican-origin/Mexican decent, (2) be ≥ 18 years old, (3) have a confirmed MASLD diagnosis (CAP score of ≥ 248 dB/m); (4) have an adult member of their social network who might be interested in participating in the study and who lives within 25 miles of the participant's residence; (5) be able to provide informed consent; and (6) be able to speak, read, and write in English and/or Spanish. Eligible social support participants must (1) be ≥ 18 years old, (2) be first degree blood relative or spouse/significant other to the intervention participants, (3) be able to provide informed consent; and (4) be able to speak, read, and write in English and/or Spanish.

Exclusion Criteria:

* Exclusion for individuals interested in the intervention component of the study will be excluded if they report (1) ongoing or recent alcohol consumption (≥21 standard drinks on average per week in men and ≥14 standard drinks on average per week in women); (2) previous diagnosis of liver cancer; (3) taking any anti-inflammatory or hepatoxic medication regularly; (4) taking medication for any form of psychiatric disorders; (5) diagnosis of depression; (6) diagnosis of autoimmune disorders; or (7) women who are pregnant or breastfeeding due to hormonal changes. Exclusion for those interested to be part of the study as social network participants will not be considered for participation if they (1) live more than 25 miles of the intervention participant's residence.

Where it's running

• UA Collaboratory for Metabolic Disease Prevention & Treatment
  Tucson, Arizona, United States Recruiting

Study contacts

• Study coordinator: Adriana Maldonado Assistant Professor, PhD
• Email: adrianamaldonado@arizona.edu
• Phone: 5206267279

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.