Comparing bone graft options for ACL reconstruction
Official title: Radiographic Findings and Clinical Outcomes After Bone Grafting Patellar Defect in ACL Reconstruction
Run by University of Arizona · NCT06975306 · Data updated 2026-11-12
This study tests which type of bone graft, either a patient's own bone or a special putty, works better for people getting surgery to fix a torn ACL.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | All |
| Enrollment | 75 (estimated) |
| Sponsor | University of Arizona Academic / other |
| Locations | 3 sites (Phoenix, Arizona and 2 other locations) |
| Status | Recruiting |
| Started | February 11, 2025 |
| Main results expected | April 30, 2027 |
| Study ends | April 30, 2027 |
| Registry record updated | August 14, 2026 |
| Trial ID | NCT06975306 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 18-40 who are scheduled for ACL reconstruction using a bone patellar tendon bone autograft.
✕Probably not a fit
Patients outside the age range of 18-41, those with prior ACL reconstruction, or individuals who are non-compliant post-operatively may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the outcomes of two different bone grafting techniques used during anterior cruciate ligament reconstruction (ACLR). Patients will be randomly assigned to receive either an autologous bone graft or a commercially available demineralized bone matrix putty. The study will assess patient-reported outcomes and clinical evaluations, including pain levels, range of motion, and radiographic changes. Participants will be monitored before and after surgery to determine the effectiveness of each graft type.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and recovery for patients undergoing ACL reconstruction.
How similar studies have gone: Previous studies have explored various grafting techniques in ACL reconstruction, indicating potential for success, but this specific comparison is less commonly tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-40 years old, * male/female/gender neutral, * all races not including vulnerable/special consideration populations, * candidate for anterior cruciate ligament reconstruction with bone patellar bone autograft, * compliant post operative course. Exclusion Criteria: * \< 18, \>41 years of age, * prior bone patellar bone anterior cruciate ligament reconstruction, * non-compliance post-operatively, * nicotine dependence.
Where it's running
-
Banner University Medical Center Phoenix
Phoenix, Arizona, United States Recruiting -
Banner Health Center Plus - Arcadia
Phoenix, Arizona, United States Recruiting -
Banner Sports Medicine Scottsdale
Scottsdale, Arizona, United States Recruiting
Study contacts
- Principal investigator: Anup Shah, MD — College of Medicine - Phoenix
- Study coordinator: Marleny Munoz
- Email: marlenymunoz@arizona.edu
- Phone: 602-793-9582
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.