Condition

Vasculitis clinical trials and research

• 20Clinical trials
• 19NIH research projects
• 6Countries

Newest Vasculitis clinical trials

All recruiting trials (20)

• Ocular Symptoms in ANCA-Associated Vasculitis

  This study tests ocular changes in adults with GPA, MPA, or related vasculitis to see how the eyes are involved.

  Recruiting Military Institute od Medicine National Research Institute · Warsaw · NCT07664709

• Systemic Vasculitis Prognosis and Outcome

  This study follows patients suspected or diagnosed with systemic vasculitis over 10 years to see how their disease progresses and what factors predict outcomes.

  Recruiting Fondazione IRCCS Policlinico San Matteo di Pavia · Pavia, Pavia · NCT07586137

• Reducing unnecessary medications in older adults with rheumatic conditions

  This project will test whether giving doctors individualized MedSafer reports plus patient EMPOWER brochures helps people 60+ with rheumatic conditions who take five or more regular medications stop or reduce risky medicines.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07278609

• Inventory of vocal cord lesions causing dysphonia in autoimmune disease patients

  This study looks at the types of vocal cord problems that cause voice issues in people with autoimmune diseases to help improve their diagnosis and treatment.

  Recruiting University Hospital, Brest · Brest · NCT06779799

• Using MRI to study kidney disease and its complications

  This study is testing if a special type of MRI can help find out more about kidney problems and their effects on heart health in people with acute kidney injury and chronic kidney disease.

  Recruiting University of Edinburgh · Edinburgh · NCT06698614

• National Registry for Rare Kidney Diseases

  This study is collecting health information from people with rare kidney diseases to help improve treatments and create better care guidelines.

  Recruiting UK Kidney Association · Bristol, South West · NCT06065852

• Longitudinal investigation of central nervous system vasculitis

  This study is trying to learn more about primary central nervous system vasculitis by following patients over three years to see how the disease affects them and to find better ways to measure its activity and outlook.

  Recruiting at 6 sites University of Pennsylvania · Rochester, Minnesota and 5 other locations · NCT05734404

• Biorepository for cardiovascular and metabolic disease research

  This study is collecting blood, urine, and stool samples from people with heart and metabolic diseases to help researchers better understand these conditions and improve care.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT05628948

• Finding blood markers for diagnosing and predicting outcomes in adult vasculitis

  This study is trying to find blood tests that can help diagnose adult vasculitis and predict how well patients will do over time, so doctors can make better treatment choices.

  Recruiting University Hospital, Tours · Tours · NCT05565885

• Identifying biomarkers in autoimmune and inflammatory diseases

  This study is trying to find specific markers in the blood of people with autoimmune diseases to help tailor their treatment and track how well it works.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris, France · NCT05383339

• Collection of biological samples to study systemic autoimmune diseases

  This study is collecting samples from people with autoimmune diseases like lupus and scleroderma to see if they can find new ways to diagnose and treat these conditions better.

  Recruiting University Hospital, Toulouse · Toulouse · NCT05251415

• Evaluating how high doses of prednisolone affect patients with inflammatory conditions

  This study is trying to see how different doses of prednisolone affect patients with inflammatory conditions by looking at their blood levels and how their bodies process the medication.

  Recruiting Imperial College London · London · NCT05012033

• Observational study on relapsing polychondritis

  This study is looking to learn more about relapsing polychondritis by regularly checking in with participants to see how the disease affects them and to find better ways to diagnose and treat it.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT04919538

• Longitudinal study of patients with vasculitis

  This study is trying to learn more about vasculitis by following patients over time to see how their disease affects them and what treatments work best.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT04413331

• Identifying Risk Factors for Heart Toxicity from Immune Checkpoint Inhibitors

  This study is trying to find out what factors might increase the risk of heart problems in people receiving immune checkpoint inhibitors for cancer treatment.

  Recruiting Groupe Hospitalier Pitie-Salpetriere · Paris · NCT04294771

• Genetic analysis of familial and pediatric vasculitis

  This study is trying to find out if certain genes in families with children who have vasculitis can help us understand why some people get this condition.

  Recruiting French Vasculitis Study Group · Paris, Île-de-France Region · NCT04006535

• Evaluating skin lesions in patients with various types of vasculitis

  This study is testing how skin lesions from different types of vasculitis look under a microscope to help doctors better understand and treat these conditions.

  Recruiting at 4 sites University of Pennsylvania · Los Angeles, California and 9 other locations · NCT03004326

• Infliximab treatment for dolichoectatic vertebrobasilar aneurysms

  This trial will test whether infliximab, a TNFα blocker, can slow aneurysm growth or reduce complications in adults with dolichoectatic vertebrobasilar aneurysms who are not candidates for surgery.

  Recruiting Phase 1/2 University of California, San Francisco · San Francisco, California · NCT02638701

• Registry for women with vasculitis during pregnancy

  This study is gathering information from pregnant women with vasculitis to understand their experiences and health outcomes during and after pregnancy.

  Recruiting University of Pennsylvania · Tampa, Florida · NCT02593565

• Registry of Chronic Wounds and Ulcers

  This study collects information from patients with chronic wounds and ulcers to see how well different treatments are working and to improve the quality of wound care.

  Recruiting U.S. Wound Registry · The Woodlands, Texas · NCT02280733

NIH-funded research (19)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• FcgR-activated neutrophils shaping T cells in kidney and vessel inflammation

  This NIH grant explores how a specific neutrophil behavior may drive harmful T-cell activity in lupus-related kidney inflammation and vasculitis, with potential to inform new treatments.

  NIH research University of Rochester · Rochester, United States · NIH-11523442

• Gut bacteria and permeability linked to Kawasaki disease in kids

  A pediatric-focused study exploring how the gut microbiome and intestinal barrier may influence Kawasaki disease and its inflammation.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11414974

• Targeting autoantigen-specific B cells in ANCA vasculitis

  A clinician-researcher at UNC is studying a way to identify and remove the specific B cells that drive ANCA vasculitis to improve long-term remission.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11400534

• Role of sex in immune-stromal cell interactions driving Kawasaki disease vasculitis

  This project looks at why Kawasaki disease causes heart problems in kids and how sex differences affect the immune cell interactions that lead to artery inflammation.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11394203

• Molecular and clinical clues to relapse in ANCA-related vasculitis

  Researchers are studying nasal and airway signals, including bacteria and gene activity, to find predictors that a person with ANCA-associated vasculitis might relapse.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11361068

• Virtual Mind-Body Resiliency for SARDs (AAV and SLE)

  A patient-facing program will test a virtual group-based mind-body approach to help people with ANCA-associated vasculitis and lupus cope with stress and improve well-being.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11357846

• Neutrophil signaling and inflammation in ANCA vasculitis

  This project uses special molecular imaging to learn how signaling proteins in neutrophils affect inflammation in people with ANCA-associated vasculitis.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11232306

• Investigating the role of a protein in a childhood vascular disease

  This study is looking at Kawasaki Disease in kids to see how a protein called HMGB1 affects the illness and heart issues, with hopes of finding new treatments for children who don’t get better with usual care.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11216258

• Sex differences in immune–vessel cell interactions in Kawasaki disease

  This project looks at how being male or female changes immune and blood-vessel cell behavior that leads to coronary artery damage in people with Kawasaki disease.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11189694

• Understanding ANCA-Associated Vasculitis Relapse from Upper Airway Changes

  This project aims to find early signs in the nose that can tell us when ANCA-associated vasculitis (AAV) might come back, helping doctors better manage the disease.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11141014

• Gut bacteria and 'leaky' gut in Kawasaki disease

  This research looks at whether changes in gut bacteria and a 'leaky' gut make Kawasaki disease worse in young children.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11133777

• NOTCH cell signals in large-vessel vasculitis (giant cell arteritis)

  Looks at whether a cell signal called NOTCH makes immune cells release succinate that fuels dangerous inflammation in people with giant cell arteritis affecting the aorta and its branches.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11099732

• Identifying proteins that regulate immune responses in a type of blood vessel inflammation

  This study is looking at how certain proteins affect the immune system in people with ANCA vasculitis, a serious autoimmune disease, to find ways to predict flare-ups and personalize treatments just for you.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11036974

• Exploring the effects of glucocorticoid treatments on patients with vasculitis

  This study is looking at how different ways of using glucocorticoids, a type of medication, affect people with vasculitis, focusing on their side effects, health outcomes, and overall quality of life, so we can find better treatment options that are easier on patients.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11032320

• Investigating how sex affects immune interactions in Kawasaki disease

  This study is looking at how Kawasaki disease affects kids and how the immune system interacts with blood vessels differently in boys and girls, with the goal of finding better treatments for those who don’t respond to regular therapies.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-10990212

• Investigating predictors of relapse in ANCA-associated vasculitis

  This study is looking at how certain genes and bacteria in the nose can help predict when people with ANCA-associated vasculitis might have a relapse, even if they aren't showing any symptoms, so doctors can better adjust their treatments and manage the condition.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-10945401

• Understanding how certain immune cells contribute to Kawasaki disease

  This study is looking at how certain immune cells, called neutrophils and eosinophils, affect Kawasaki disease in kids, with the hope of finding better treatments for those who don’t get better with regular medicine.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-10903812

• Investigating how Sirt-1 affects inflammation in Kawasaki Disease

  This study is looking at Kawasaki Disease in kids and how a specific pathway in the body might help reduce inflammation in their blood vessels, with hopes of finding better treatments to keep their hearts healthy.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-10890070

• Exploring the role of a protein in a type of blood vessel inflammation

  This study is looking at how a protein called alpha-1 antitrypsin influences immune cells in people with ANCA-associated vasculitis, a rare autoimmune disease, to help find better ways to treat and predict flare-ups for those affected.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-10887261

Related topics

Quick answers

How many Vasculitis clinical trials are recruiting right now?

20, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (7 trials), France (7 trials), Canada (3 trials), United Kingdom (3 trials), Poland (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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