Finding blood markers for diagnosing and predicting outcomes in adult vasculitis
Search for BIO Diagnostic and Prognostic Markers in Adult VAScularitis
University Hospital, Tours · NCT05565885
This study is trying to find blood tests that can help diagnose adult vasculitis and predict how well patients will do over time, so doctors can make better treatment choices.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 225 (estimated) |
| Ages | 16 Years and up |
| Sex | All |
| Sponsor | University Hospital, Tours (other) |
| Locations | 1 site (Tours) |
| Trial ID | NCT05565885 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify reliable diagnostic and prognostic biomarkers for adult vasculitis, a condition currently diagnosed through invasive procedures like biopsies. Conducted at the University Hospital in Tours, the study will collect blood samples at diagnosis, and at one, three, and twelve months, as well as during any relapses. The focus is on both metabolomic and immunologic markers to improve patient management and treatment decisions.
Who should consider this trial
Good fit: Ideal candidates include adults over 16 years old with active vasculitis, either newly diagnosed or experiencing a relapse.
Not a fit: Patients who have recently received corticosteroids, immunosuppressive drugs, or biotherapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to non-invasive blood tests that improve the diagnosis and management of adult vasculitis.
How similar studies have performed: While there is limited success in finding reliable biomarkers for vasculitis, this approach is novel and aims to fill a significant gap in current diagnostic methods.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 16 years * Active vasculitis, new diagnosis or relapse * IgA vasculitis * ANCA vasculitis * Giant cell arteritis Exclusion Criteria: * Person who has objected to the processing of data * Pregnant woman * Patient positive for HIV, HBV, HCV * Treatment in the previous month with corticosteroids, immunosuppressive drugs or biotherapy. * Patient unable to understand the information leaflet * Adult under guardianship or curatorship
Where this trial is running
Tours
- University hospital — Tours, France (RECRUITING)
Study contacts
- Study coordinator: Alexandra Audemard verger
- Email: alexandra.audemardverger@univ-tours.fr
- Phone: 02 47 47 37 15
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Vasculitis, biomarkers, diagnosis, prognosis