Finding blood markers for diagnosing and predicting outcomes in adult vasculitis
Official title: Search for BIO Diagnostic and Prognostic Markers in Adult VAScularitis
Run by University Hospital, Tours · NCT05565885 · Data updated 2026-11-12
This study is trying to find blood tests that can help diagnose adult vasculitis and predict how well patients will do over time, so doctors can make better treatment choices.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 16 Years and up |
| Sex | All |
| Enrollment | 225 (estimated) |
| Sponsor | University Hospital, Tours Academic / other |
| Locations | 1 site (Tours) |
| Status | Recruiting |
| Started | November 22, 2022 |
| Main results expected | December 2037 |
| Study ends | December 2037 |
| Registry record updated | May 29, 2025 |
| Trial ID | NCT05565885 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 16 years old with active vasculitis, either newly diagnosed or experiencing a relapse.
✕Probably not a fit
Patients who have recently received corticosteroids, immunosuppressive drugs, or biotherapy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to identify reliable diagnostic and prognostic biomarkers for adult vasculitis, a condition currently diagnosed through invasive procedures like biopsies. Conducted at the University Hospital in Tours, the study will collect blood samples at diagnosis, and at one, three, and twelve months, as well as during any relapses. The focus is on both metabolomic and immunologic markers to improve patient management and treatment decisions.
Why it matters
Potential benefit: If successful, this study could lead to non-invasive blood tests that improve the diagnosis and management of adult vasculitis.
How similar studies have gone: While there is limited success in finding reliable biomarkers for vasculitis, this approach is novel and aims to fill a significant gap in current diagnostic methods.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 16 years * Active vasculitis, new diagnosis or relapse * IgA vasculitis * ANCA vasculitis * Giant cell arteritis Exclusion Criteria: * Person who has objected to the processing of data * Pregnant woman * Patient positive for HIV, HBV, HCV * Treatment in the previous month with corticosteroids, immunosuppressive drugs or biotherapy. * Patient unable to understand the information leaflet * Adult under guardianship or curatorship
Where it's running
-
University hospital
Tours, France Recruiting
Study contacts
- Study coordinator: Alexandra Audemard verger
- Email: alexandra.audemardverger@univ-tours.fr
- Phone: 02 47 47 37 15
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.