Observational study on relapsing polychondritis
Longitudinal Study for Relapsing Polychondritis
University of Pennsylvania · NCT04919538
This study is looking to learn more about relapsing polychondritis by regularly checking in with participants to see how the disease affects them and to find better ways to diagnose and treat it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Sex | All |
| Sponsor | University of Pennsylvania (other) |
| Locations | 1 site (Philadelphia, Pennsylvania) |
| Trial ID | NCT04919538 on ClinicalTrials.gov |
What this trial studies
This study focuses on relapsing polychondritis (RP), a rare systemic inflammatory disease that causes recurrent inflammation of cartilage and can affect various organ systems. The research aims to understand the pathogenesis of RP through a longitudinal cohort approach, involving regular study visits every six months or annually. Participants will undergo blood and urine collection, physical exams, and complete questionnaires to assess disease activity and health status, which will help generate insights into the disease's mechanisms and potential new diagnostic and treatment strategies.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with relapsing polychondritis.
Not a fit: Patients who are unable to provide consent or are minors may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and treatment strategies for patients with relapsing polychondritis.
How similar studies have performed: While the approach is novel in its longitudinal and multicenter design, similar studies have shown promise in understanding rare diseases.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1\. Any subject considered to have a diagnosis of relapsing polychondritis according to the investigator. Exclusion Criteria: * 1\. Inability to provide consent, or in the case of minors, assent.
Where this trial is running
Philadelphia, Pennsylvania
- University of Pennsylvania — Philadelphia, Pennsylvania, United States (RECRUITING)
Study contacts
- Principal investigator: Shubhasree Banerjee, MD — University of Pennsylvania
- Study coordinator: Carol McAlear
- Email: cmcalear@upenn.edu
- Phone: 7813214567
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Relapsing Polychondritis, Vasculitis, RP