Exploring the effects of glucocorticoid treatments on patients with vasculitis
Official title: Understanding Glucocorticoid Toxicity: The Impact of Glucocorticoid Regimens on Toxicities, Clinical Outcomes, and Quality-of-Life in Vasculitis
Funded at Massachusetts General Hospital · NIH-11032320 · Data updated 2026-11-12
This study is looking at how different ways of using glucocorticoids, a type of medication, affect people with vasculitis, focusing on their side effects, health outcomes, and overall quality of life, so we can find better treatment options that are easier on patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | May 1, 2025 |
| Project end | April 30, 2030 |
| Funding year | 2025 |
| Award (this year) | $176,040 |
| NIH project number | 1K23AR085181-01 |
| Project ID | NIH-11032320 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are diagnosed with ANCA-associated vasculitis and are undergoing glucocorticoid treatment.
✕Less likely to help
Patients who are not currently receiving glucocorticoid treatments or those with other forms of vasculitis unrelated to ANCA may not benefit from this research.
What this research studies
This research investigates how different glucocorticoid treatment regimens affect the toxicities, clinical outcomes, and quality of life for patients suffering from vasculitis. The study aims to gather data on the adverse effects associated with these treatments and how they impact patients' overall health and well-being. By analyzing patient outcomes and experiences, the research seeks to improve treatment strategies and minimize harmful side effects. Patients will be closely monitored and their feedback will be integral to understanding the real-world implications of glucocorticoid use.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatment options for patients with vasculitis, enhancing their quality of life.
How similar studies have gone: Previous research has shown promising results in understanding glucocorticoid toxicity in other conditions, indicating that this approach may yield valuable insights for vasculitis as well.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Patel, Naomi Julia — Massachusetts General Hospital
- Study coordinator: Patel, Naomi Julia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.