Ocular Symptoms in ANCA-Associated Vasculitis
Official title: Ocular Manifestations of Granulomatosis With Polyangiitis.
Run by Military Institute od Medicine National Research Institute · NCT07664709 · Data updated 2026-11-12
This study tests ocular changes in adults with GPA, MPA, or related vasculitis to see how the eyes are involved.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | Military Institute od Medicine National Research Institute Academic / other |
| Drugs / interventions | rituximab, methotrexate, cyclophosphamide |
| Locations | 1 site (Warsaw) |
| Status | Recruiting |
| Started | March 1, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | June 24, 2026 |
| Trial ID | NCT07664709 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) with ANCA-associated vasculitis (GPA, MPA, or related conditions), including both treatment-naïve and treated patients.
✕Probably not a fit
Patients without ocular involvement or inability to undergo eye imaging may not derive direct benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study uses optical coherence tomography angiography to characterize eye involvement in ANCA-associated vasculitis. It includes adults with GPA, MPA, or related conditions, whether or not they are currently treated. The goal is to describe ocular manifestations and their relationship to systemic disease activity. Data will be collected from participants at the Military Institute of Medicine in Warsaw. The study does not involve experimental treatment and aims to improve understanding of eye-related complications in this patient group.
Why it matters
Potential benefit: If successful, the study could improve recognition and monitoring of eye involvement in AAV, potentially guiding eye-specific management.
How similar studies have gone: Previous research has shown ocular involvement in AAV is possible; this approach using OCTA is a newer, targeted way to characterize it.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: ANCA positive vasculitis age 18- no limit patients with onset od the disease and patients already under treatment \- Exclusion Criteria: * no consent for ophthalmic examination * inability to udergo ophthalmic examination
Where it's running
-
Military Institute of Medicine National Research Institute
Warsaw, Poland Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.