Condition

Pelvic Pain clinical trials and research

• 24Clinical trials
• 35NIH research projects
• 9Countries

Newest Pelvic Pain clinical trials

All recruiting trials (24)

• Personalized Exercise Recommendations for Chronic Pelvic Pain

  This study tests if an AI-powered, personalized exercise plan can help people with chronic pelvic pain see if tailored workouts work better than standard guidance.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07810218

• Samphire Guided Care for Wellbeing at Work

  This study tests a 12-week digital program with at-home neuromodulation to see if it helps women with menstrual or perimenopausal symptoms feel better at work and in daily life.

  Recruiting Samphire Group, Inc. · San Francisco, California · NCT07679074

• High-intensity interval training to reduce menstrual pain and improve menstrual health in women with primary dysmenorrhea

  This 12-week program will try supervised online high-intensity interval training plus a menstrual health workshop to see if it reduces menstrual pain and improves quality of life for women aged 18–40 with primary dysmenorrhea.

  Recruiting University of Alcala · Alcalá de Henares, Madrid · NCT07391930

• PEMM for women with chronic low back pain and urinary leakage

  This study will try pelvic external myofascial mobilization (PEMM) with core exercises to see if it lowers pain, reduces disability, and improves urinary leakage and mental health in women with chronic low back pain and urinary incontinence.

  Recruiting Hamad Medical Corporation · Doha, Baladiyat ad Dawhah · NCT07351851

• Electroacupuncture for pelvic pain in women with suspected endometriosis

  This study tests whether a series of electroacupuncture sessions can reduce pelvic pain in women awaiting diagnostic laparoscopy for suspected endometriosis.

  Recruiting St. Olavs Hospital · Trondheim · NCT07305025

• Franco-European Institute of Endometriosis long-term outcomes cohort

  This cohort will follow women with confirmed pelvic endometriosis to see if different medical and surgical treatments lead to better long-term symptoms, quality of life, recurrence rates, and fertility outcomes.

  Recruiting Clinique Tivoli Ducos · Bordeaux · NCT07243587

• Estradiol-linked inflammation and nerve sensitization in endometriosis pelvic pain treated with relugolix

  This study will try relugolix combination therapy to see if it reduces pelvic pain, inflammation, and pain sensitivity in premenopausal women with moderate-to-severe endometriosis-related pelvic pain.

  Recruiting Phase 3 University of Michigan · Ann Arbor, Michigan · NCT07100782

• Treatment of pelvic pain using a wearable LED device

  This study is testing whether wearing a special LED device can help women with pelvic pain feel better.

  Recruiting Peking University Third Hospital · Beijing, Beijing Municipality · NCT06982989

• Alcohol sclerotherapy for pelvic pain and quality of life in ovarian endometrioma

  This trial will try ultrasound-guided alcohol sclerotherapy to see if it reduces pelvic pain and improves quality of life in women aged 18–45 with ovarian endometriomas compared with expectant management.

  Recruiting at 10 sites Hospital Universitari de Bellvitge · Palma de Mallorca, Balearic Islands and 25 other locations · NCT06955221

• Comparing perineal massage therapy and an intravaginal device for postpartum pain relief

  This study is testing whether perineal massage or a special intravaginal device can help new mothers feel less pain after giving birth.

  Recruiting Phase 2 Instituto Sexológico Murciano · Murcia, Murcia · NCT06921174

• Home Pelvic Floor Improvement Trainer for kids

  This study tests a home biofeedback device to help kids with pelvic floor and voiding problems see if it eases symptoms and can replace or supplement in-person physical therapy.

  Recruiting University of Colorado, Denver · Aurora, Colorado · NCT06909539

• Using NSAIDs to treat menstrual pain and prevent chronic pelvic pain

  This study is testing if taking naproxen sodium can help young adults with painful periods feel better and possibly prevent long-term pelvic pain.

  Recruiting Phase 4 Endeavor Health · Evanston, Illinois · NCT06861920

• Comparing a vibrating pelvic floor device to traditional vaginal dilators for treating entry dyspareunia

  This study is testing whether a new vibrating pelvic floor device can help women with pain during sex feel better compared to using traditional vaginal dilators.

  Recruiting Medstar Health Research Institute · Washington D.C., District of Columbia · NCT06840314

• Impact of Barbed Suture on Uterine Healing After Cesarean Section

  This study tests if using barbed sutures instead of regular sutures during cesarean sections helps pregnant women heal better and reduces complications.

  Recruiting Hospital Clinic of Barcelona · Barcelona · NCT06691750

• Group care program for treating endometriosis-related pain

  This study is testing a new group care program called PEEPS to see if it can help people aged 18 to 48 with endometriosis-related pain feel better compared to those who just get regular support.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT06549985

• Acupuncture treatment for chronic pelvic pain in women

  This study is testing if a special acupuncture treatment can help women with chronic pelvic pain feel better compared to regular pain management methods.

  Recruiting Mike O'Callaghan Military Hospital · Nellis Air Force Base, Nevada · NCT06388590

• Ovarian and pelvic vein embolization for women with chronic pelvic pain and pelvic varices

  This trial tests whether embolizing ovarian and pelvic veins reduces chronic pelvic pain and improves quality of life in premenopausal women with pelvic varicose veins.

  Recruiting at 4 sites Weill Medical College of Cornell University · Kansas City, Kansas and 4 other locations · NCT06168058

• Understanding pain in patients with endometriosis and pelvic pain

  This study looks at what causes chronic pelvic pain in people with and without endometriosis and checks how pain and hormone levels change after surgery to remove endometriosis lesions.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT06101303

• Pre-rehabilitation for women receiving pelvic radiation therapy

  This study is testing if adding pelvic health physical therapy to radiation treatment can help women with certain cancers feel better and improve their quality of life.

  Recruiting at 3 sites Indiana University · Avon, Indiana and 2 other locations · NCT06059586

• Evaluating women's sexual quality of life after minimally invasive surgery for benign ovarian conditions

  This study is testing if a new type of surgery for ovarian conditions affects women's sexual quality of life differently than traditional surgery.

  Recruiting University Hospital, Geneva · Geneva · NCT05761275

• Evaluating a new device for vaginal dilation after pelvic radiation therapy

  This study is testing a new device that helps women who have had pelvic radiation therapy to safely and comfortably manage vaginal dilation and see if it improves their quality of life and reduces pelvic pain.

  Recruiting Hyivy Health Inc · Kitchener, Ontario · NCT05648253

• Comparing online cognitive behavioral therapy and a single session pain relief intervention for chronic pain

  This study is testing whether an 8-session online therapy program or a one-time pain relief session works better for people with chronic pain, like those with lupus or pelvic pain.

  Recruiting at 3 sites Stanford University · Phoenix, Arizona and 4 other locations · NCT05612750

• Platelet-rich plasma to prevent uterine scar problems after cesarean

  This test will see if applying your own platelet-rich plasma to the uterine incision at an elective term cesarean can reduce scar-related bleeding, pain, and menstrual problems.

  Recruiting The University of Texas Health Science Center, Houston · Ramat Gan, Center · NCT05224726

• Measuring pain relief from gonadal vein embolization for pelvic congestion syndrome

  This study is testing how much pain relief women with pelvic congestion syndrome get from a procedure called gonadal vein embolization.

  Recruiting University of Kansas Medical Center · Kansas City, Kansas · NCT03794466

NIH-funded research (35)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Measuring pelvic floor muscle fitness in women with myofascial pelvic pain

  A non-invasive imaging method uses near-infrared spectroscopy to map how well pelvic floor muscles work in adult women with myofascial pelvic pain.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11592207

• Decoding Dysmenorrhea: Longitudinal Pain Phenotypes in Adolescents and Young Adults

  A study on how menstrual pain develops over time in teenagers and young adults, exploring brain and behavior to understand why some have ongoing pain.

  NIH research Mclean Hospital · Belmont, United States · NIH-11447102

• Exploring allergy-based triggers to prevent UCPPS flare-ups

  A short, patient-friendly study will look at whether allergy-related antibodies can help predict and prevent flare-ups in people with urologic chronic pelvic pain syndrome.

  NIH research Washington University · Saint Louis, United States · NIH-11445166

• Targeted pelvic warmth/cooling device to relieve pelvic pain

  A low-cost, portable device uses controlled temperature changes to soothe pelvic pain from conditions like endometriosis and bladder issues, with the goal of reducing pain and inflammation without opioids.

  NIH research H3pelvic Therapy Systems, INC. · Lewisville, United States · NIH-11410620

• Dual Cromolyn-Cetirizine oral capsule to help men with chronic pelvic pain

  A new oral medicine combining cromolyn sodium and cetirizine is being developed to help adults with chronic prostatitis/chronic pelvic pain by targeting immune and nerve-related pathways.

  NIH research Dolor Therapeutics, LLC · Chicago, United States · NIH-11407121

• Sacral nerve stimulation for chronic pelvic pain

  A study to see if a minimally invasive nerve-stimulation therapy can help reduce chronic pelvic pain and improve quality of life in adult women.

  NIH research William Beaumont Hospital Research Inst · Royal Oak, United States · NIH-11378507

• Neuron-satellite glial signaling in pelvic pain and pelvic organ cross-sensitization

  This grant explores how nerve cells and nearby support cells in the pelvis communicate and contribute to chronic pelvic pain conditions like IC/BPS and IBS, with the goal of identifying new ways to relieve pain.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11377583

• Why menstrual pain becomes chronic pelvic pain

  We will follow young women with menstrual pain, including those with bladder sensitivity, to learn who develops ongoing pelvic pain and which early signs predict it.

  NIH research Endeavor Health Clinical Operations · Evanston, United States · NIH-11349686

• How early inflammation or stress may cause long-term pelvic and bladder pain

  This project looks at how early-life inflammation or stress can change nerve signaling to the bladder and pelvis and lead to long-term pelvic pain in adults.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11349655

• Sacral Neuromodulation for Chronic Pelvic Pain

  This research explores if a treatment called sacral neuromodulation can help women who experience ongoing pelvic pain.

  NIH research William Beaumont Hospital Research Inst · Royal Oak, United States · NIH-11168899

• Brain immune cells and gut imbalance in pelvic pain

  This project looks at whether brain immune cells called microglia respond to changes in gut bacteria through a sensor called TLR4 and whether that pathway helps cause chronic pelvic pain.

  NIH research Northwestern University · Chicago, United States · NIH-11162291

• Understanding nerve and support cell communication in chronic pelvic pain

  This research explores how nerve cells and their support cells in the pelvis communicate, aiming to understand the causes of chronic pelvic pain, interstitial cystitis, and irritable bowel syndrome.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11161510

• A brief behavioral treatment for chronic pelvic pain

  This project is testing a short behavioral therapy to help people manage chronic pelvic pain and related conditions like irritable bowel syndrome.

  NIH research State University of New York at Buffalo · Amherst, United States · NIH-11159501

• Overcome Pelvic Pain (POPPY)

  This project offers trauma-informed yoga for women with chronic pelvic pain to help reduce pain, anxiety, and improve daily function.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11144921

• Chemical Clues in Chronic Pelvic Pain

  This project looks for unique chemical patterns in the body that could help us better understand and treat chronic pelvic pain in men and women.

  NIH research Washington University · Saint Louis, United States · NIH-11143622

• Using glial cells to reduce visceral pain in bladder conditions

  This study is looking at how certain cells in the nervous system can be activated to help reduce the pain that comes with chronic pelvic pain syndrome, especially for those dealing with bladder issues, and it aims to find new treatment options that could eventually help people like you.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11140281

• A new method for precise botulinum toxin injections to treat chronic pelvic pain

  This study is testing a new way to give botulinum injections to help women with chronic pelvic pain, aiming to make the injections more accurate so they can feel better and have fewer side effects.

  NIH research Hillmed INC · Katy, United States · NIH-11139696

• Understanding the causes of chronic pelvic pain in women

  This study is looking at why some young women with menstrual pain end up with long-lasting pelvic pain, and it will follow them for two years to find out what factors might increase the risk of developing this chronic pain.

  NIH research Endeavor Health Clinical Operations · Evanston, United States · NIH-11136242

• Understanding chronic pelvic pain and its causes

  This study is looking into how early life experiences and stress might change the way our bodies feel pain in the pelvic area, which could help find new ways to treat chronic pelvic pain conditions like interstitial cystitis and chronic prostatitis.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11116883

• Investigating how nerve growth factors affect chronic pelvic pain in women and adolescents with endometriosis

  This study is looking at how certain nerve growth factors might be linked to chronic pelvic pain in women and teens with endometriosis, especially for those who still feel pain after surgery, to help find new ways to treat their discomfort.

  NIH research Merrimack College · North Andover, United States · NIH-11087983

• Investigating how hemopexin affects pelvic pain in urologic conditions

  This study is looking at how a protein called hemopexin and stress might affect pelvic pain in people with chronic pelvic pain syndrome, and it aims to find new ways to help manage this condition.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11069005

• Understanding how menstrual pain can lead to chronic pelvic pain

  This study is looking at how painful periods might lead to long-term pelvic pain and how inflammation and nerve changes play a role, so we can find better ways to help women manage their pain and prevent it from getting worse.

  NIH research Endeavor Health Clinical Operations · Evanston, United States · NIH-11023728

• Measuring pelvic floor muscle health in women with chronic pelvic pain

  This study is looking at how well the pelvic floor muscles are working in women with myofascial pelvic pain, using a gentle method that measures blood flow and oxygen levels during muscle contractions, to help improve understanding and treatment of this common pain condition.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-10954686

• Using sacral neuromodulation to help manage chronic pelvic pain in women

  This study is looking at whether a gentle treatment called sacral neuromodulation can help adult women who are dealing with chronic pelvic pain, aiming to improve their quality of life and address any related issues.

  NIH research William Beaumont Hospital Research Inst · Royal Oak, United States · NIH-10932430

• Investigating how nerve and glial cell interactions contribute to pelvic pain

  This study is looking at how certain cells in the nervous system interact with each other to help us understand why some people experience ongoing pelvic pain, like in conditions such as interstitial cystitis or irritable bowel syndrome, with the hope of finding better ways to treat this pain.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-10932346

• A treatment approach for chronic pelvic pain in women

  This study is looking at different ways to help women with chronic pelvic pain feel better, using methods like therapy, acupressure, and exercise, to find the best treatments that fit each person's needs.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10920403

• Improving treatment for chronic pelvic pain in men

  This study is looking to create a new oral medication to help men under 50 who suffer from chronic prostatitis/chronic pelvic pain syndrome, by combining two types of medicine that have shown promise, and it will first test these new formulas in dogs to find the best one before trying it in people.

  NIH research Dolor Therapeutics, LLC · Chicago, United States · NIH-10918611

• Investigating the role of food-specific antibodies in chronic pelvic pain conditions.

  This study is looking at how certain foods might affect people with chronic pelvic pain, like interstitial cystitis and chronic prostatitis, to find out if changing what you eat can help ease your symptoms.

  NIH research Washington University · Saint Louis, United States · NIH-10914073

• Investigating how gut bacteria affect pelvic pain through immune cells

  This study is looking at how the bacteria in our gut might affect chronic pelvic pain by seeing how certain immune cells in the brain react to changes in those bacteria, using mice to help us understand this connection better.

  NIH research Northwestern University at Chicago · Chicago, United States · NIH-10911276

• A new treatment approach for chronic pelvic pain conditions

  This study is testing a short therapy program that helps people with chronic pelvic pain learn ways to manage their symptoms, and it's open to anyone dealing with this kind of pain, including those with related issues like irritable bowel syndrome or fibromyalgia.

  NIH research State University of New York at Buffalo · Amherst, United States · NIH-10896160

• A program to help women manage chronic pelvic pain through yoga

  This study is exploring how yoga can help women with chronic pelvic pain feel better by teaching them relaxing techniques and mindful practices that they can easily do on their own.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10881523

• Understanding the role of the immune system in chronic pelvic pain

  This study is looking at how inflammation and immune responses might affect the nervous system in people with Urologic Chronic Pelvic Pain Syndrome (UCPPS) and other pain issues, to help find better ways to treat this painful condition.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10767260

• A device for pain relief using temperature modulation

  This study is testing a new, easy-to-use device that helps relieve pelvic pain by using heat, so you can feel better without relying on painkillers like opioids.

  NIH research H3pelvic Therapy Systems, INC. · Lewisville, United States · NIH-10760002

• A new device to help female cancer survivors with pelvic pain and painful intercourse

  This study is testing a new device to help female cancer survivors who have ongoing pelvic pain and discomfort during intimacy, making it easier and more comfortable for them to manage their symptoms.

  NIH research Cervu, INC · Cary, United States · NIH-10759026

• Understanding pelvic pain and musculoskeletal health in women

  This study is looking into chronic pelvic pain in women, which affects many people, to better understand how it connects to conditions like endometriosis and anxiety, and to find ways to improve treatment for those who are struggling with this pain.

  NIH research Loyola University Chicago · Maywood, United States · NIH-10705656

Related topics

Quick answers

How many Pelvic Pain clinical trials are recruiting right now?

24, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (13 trials), Spain (4 trials), Norway (1 trial), Israel (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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