Condition

Chronic Pelvic Pain Syndrome clinical trials and research

• 13Clinical trials
• 9NIH research projects
• 6Countries

Newest Chronic Pelvic Pain Syndrome clinical trials

All recruiting trials (13)

• Immune profile test for women with chronic pelvic pain and endometriosis

  This study tests a functional immune test to see if immune profiles differ in women with chronic pelvic pain and endometriosis who aren’t responding to first-line treatments.

  Recruiting Centre Hospitalier Universitaire de Nice · Nice, Alpes-Maritimes · NCT07429773

• Remote pelvic floor yoga program for chronic pelvic pain

  This study tests whether a remote yoga program can help women with chronic pelvic pain feel better compared to a regular physical conditioning program.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06778070

• Comparing two methods for pudendal nerve block in pelvic pain treatment

  This study is testing two different ways to give a nerve block to see which one helps women with pelvic pain feel better.

  Recruiting Phase 4 University of Louisville · Louisville, Kentucky · NCT06644261

• Closed-loop spinal cord stimulation for chronic pelvic pain — effectiveness and safety

  This study will test whether closed-loop spinal cord stimulation can safely reduce chronic pelvic pain in adults whose pain has not improved with standard treatments.

  Recruiting Stanford University · Redwood City, California · NCT06377969

• Using acupoint application to improve pelvic inflammatory disease and chronic pelvic pain

  This study is testing if a new type of pain-relief patch can help people with pelvic inflammatory disease and chronic pelvic pain feel better compared to regular patches and a placebo.

  Recruiting Beijing Hospital of Integrated Traditional Chinese and Western Medicine · Beijing · NCT06360965

• Tele-rehabilitation for chronic pelvic pain in endometriosis

  This study is testing a tele-rehabilitation program to see if it can help women with endometriosis and chronic pelvic pain feel better through online sessions that include pain education and exercises.

  Recruiting University of Alcala · Alcalà de Henares, Madrid · NCT06209346

• Ovarian and pelvic vein embolization for women with chronic pelvic pain and pelvic varices

  This trial tests whether embolizing ovarian and pelvic veins reduces chronic pelvic pain and improves quality of life in premenopausal women with pelvic varicose veins.

  Recruiting at 4 sites Weill Medical College of Cornell University · Kansas City, Kansas and 4 other locations · NCT06168058

• Esketamine for treating chronic pain from endometriosis

  This study is testing whether esketamine can help women with endometriosis feel less chronic pelvic pain compared to a placebo.

  Recruiting Phase 3 Reinier de Graaf Groep · Delft · NCT06161805

• Using sacral neuromodulation to treat chronic pelvic pain in women

  This study is testing a new treatment called sacral neuromodulation to see if it can help women aged 22-70 with chronic pelvic pain feel better and improve their quality of life.

  Recruiting Corewell Health East · Royal Oak, Michigan · NCT06150599

• Pelvic floor training for men with chronic pelvic pain

  This study is testing if pelvic floor exercises and biofeedback can help men with chronic pelvic pain feel better over six months compared to those who continue their usual treatment.

  Recruiting Region Stockholm · Stockholm · NCT06115083

• Comparing low-intensity shockwave and radial wave treatments for erectile dysfunction and pelvic pain

  This study is testing whether focused shockwave therapy or radial wave therapy can help men with erectile dysfunction and people with chronic pelvic pain feel better.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT05868668

• Using a smartphone app to track pain and mood changes

  This study is testing a smartphone app to track pain and mood changes in people with chronic pain and healthy individuals to see how these factors affect pain over time.

  Recruiting Brown University · Providence, Rhode Island · NCT05754190

• A program to ease pelvic pain through cognitive behavioral therapy

  This study is testing a short program of cognitive behavioral therapy to see if it can help people with chronic pelvic pain feel better compared to regular patient education.

  Recruiting State University of New York at Buffalo · Los Angeles, California and 2 other locations · NCT05127616

NIH-funded research (9)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Exploring allergy-based triggers to prevent UCPPS flare-ups

  A short, patient-friendly study will look at whether allergy-related antibodies can help predict and prevent flare-ups in people with urologic chronic pelvic pain syndrome.

  NIH research Washington University · Saint Louis, United States · NIH-11445166

• Dual Cromolyn-Cetirizine oral capsule to help men with chronic pelvic pain

  A new oral medicine combining cromolyn sodium and cetirizine is being developed to help adults with chronic prostatitis/chronic pelvic pain by targeting immune and nerve-related pathways.

  NIH research Dolor Therapeutics, LLC · Chicago, United States · NIH-11407121

• A brief behavioral treatment for chronic pelvic pain

  This project is testing a short behavioral therapy to help people manage chronic pelvic pain and related conditions like irritable bowel syndrome.

  NIH research State University of New York at Buffalo · Amherst, United States · NIH-11159501

• Chemical Clues in Chronic Pelvic Pain

  This project looks for unique chemical patterns in the body that could help us better understand and treat chronic pelvic pain in men and women.

  NIH research Washington University · Saint Louis, United States · NIH-11143622

• Using glial cells to reduce visceral pain in bladder conditions

  This study is looking at how certain cells in the nervous system can be activated to help reduce the pain that comes with chronic pelvic pain syndrome, especially for those dealing with bladder issues, and it aims to find new treatment options that could eventually help people like you.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11140281

• Improving treatment for chronic pelvic pain in men

  This study is looking to create a new oral medication to help men under 50 who suffer from chronic prostatitis/chronic pelvic pain syndrome, by combining two types of medicine that have shown promise, and it will first test these new formulas in dogs to find the best one before trying it in people.

  NIH research Dolor Therapeutics, LLC · Chicago, United States · NIH-10918611

• Investigating the role of food-specific antibodies in chronic pelvic pain conditions.

  This study is looking at how certain foods might affect people with chronic pelvic pain, like interstitial cystitis and chronic prostatitis, to find out if changing what you eat can help ease your symptoms.

  NIH research Washington University · Saint Louis, United States · NIH-10914073

• A new treatment approach for chronic pelvic pain conditions

  This study is testing a short therapy program that helps people with chronic pelvic pain learn ways to manage their symptoms, and it's open to anyone dealing with this kind of pain, including those with related issues like irritable bowel syndrome or fibromyalgia.

  NIH research State University of New York at Buffalo · Amherst, United States · NIH-10896160

• Understanding the role of the immune system in chronic pelvic pain

  This study is looking at how inflammation and immune responses might affect the nervous system in people with Urologic Chronic Pelvic Pain Syndrome (UCPPS) and other pain issues, to help find better ways to treat this painful condition.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10767260

Related topics

Quick answers

How many Chronic Pelvic Pain Syndrome clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (8 trials), China (1 trial), Spain (1 trial), Sweden (1 trial), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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