NIH-funded research R01 grant

Sacral Neuromodulation for Chronic Pelvic Pain

Official title: Sacral neuromodulation for the management of chronic pelvic pain

Funded at William Beaumont Hospital Research Inst · NIH-11168899 · Data updated 2026-11-12

This research explores if a treatment called sacral neuromodulation can help women who experience ongoing pelvic pain.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWilliam Beaumont Hospital Research Inst
NIH-funded
Lab location1 site (Royal Oak, United States)
Project startSeptember 20, 2023
Project endJuly 31, 2028
Funding year2025
Award (this year)$574,981
NIH project number5R01DK138839-03
Project IDNIH-11168899 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adult women who have experienced non-cancerous pelvic pain for at least six months.

Less likely to help

Patients whose pelvic pain is caused by cancer or those who have not had pain for at least six months may not benefit from this specific approach.

What this research studies

Chronic pelvic pain is a challenging condition that affects many women, causing significant discomfort and impacting daily life. It can be hard to find the exact cause of this pain, and it often comes with other issues like anxiety or sleep problems. This project looks at sacral neuromodulation, a gentle procedure that uses mild electrical pulses to nerves in the lower back. We hope this approach can help improve pain and related symptoms for those living with chronic pelvic pain.

Why it matters

Potential benefit: If successful, this approach could offer a new, effective treatment option for women suffering from chronic pelvic pain, potentially improving their quality of life.

How similar studies have gone: While previous studies have shown that sacral neuromodulation can reduce pelvic pain as a secondary outcome, this project is a novel prospective effort to specifically confirm its effectiveness for chronic pelvic pain.

Where this research is happening

  • William Beaumont Hospital Research Inst
    Royal Oak, United States
    Active

Researchers

  • Principal investigator: Peters, Kenneth M — William Beaumont Hospital Research Inst
  • Study coordinator: Peters, Kenneth M

Related research

Other NIH-funded projects on the same topics.

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  • Dual Cromolyn-Cetirizine oral capsule to help men with chronic pelvic pain

    A new oral medicine combining cromolyn sodium and cetirizine is being developed to help adults with chronic prostatitis/chronic pelvic pain by targeting immune and nerve-related pathways.

    NIH research Dolor Therapeutics, LLC · Chicago, United States · NIH-11407121

  • Sacral nerve stimulation for chronic pelvic pain

    A study to see if a minimally invasive nerve-stimulation therapy can help reduce chronic pelvic pain and improve quality of life in adult women.

    NIH research William Beaumont Hospital Research Inst · Royal Oak, United States · NIH-11378507

  • Why menstrual pain becomes chronic pelvic pain

    We will follow young women with menstrual pain, including those with bladder sensitivity, to learn who develops ongoing pelvic pain and which early signs predict it.

    NIH research Endeavor Health Clinical Operations · Evanston, United States · NIH-11349686

  • A brief behavioral treatment for chronic pelvic pain

    This project is testing a short behavioral therapy to help people manage chronic pelvic pain and related conditions like irritable bowel syndrome.

    NIH research State University of New York at Buffalo · Amherst, United States · NIH-11159501

  • Chemical Clues in Chronic Pelvic Pain

    This project looks for unique chemical patterns in the body that could help us better understand and treat chronic pelvic pain in men and women.

    NIH research Washington University · Saint Louis, United States · NIH-11143622

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.