Measuring pain relief from gonadal vein embolization for pelvic congestion syndrome

Quantification of Pain Relief With Gonadal Vein Embolization for Pelvic Congestion Syndrome

Observational University of Kansas Medical Center · NCT03794466

This study is testing how much pain relief women with pelvic congestion syndrome get from a procedure called gonadal vein embolization.

Quick facts

Study typeObservational
Enrollment30 (estimated)
Ages18 Years and up
SexFemale
SponsorUniversity of Kansas Medical Center Academic / other
Locations1 site (Kansas City, Kansas)
Trial IDNCT03794466 on ClinicalTrials.gov

What this trial studies

This observational study aims to quantify the pain relief experienced by female patients undergoing gonadal vein embolization for pelvic congestion syndrome (PCS). It will also identify clinical and imaging factors that may predict a positive or poor response to the treatment. Chronic pelvic pain affects a significant number of women, and this study seeks to provide insights into the effectiveness of coil embolization as a treatment option. The study will involve patients treated at the University of Kansas Medical Center over a specified period.

Who should consider this trial

Good fit: Ideal candidates for this study are female patients aged 18 and older who have been diagnosed with pelvic congestion syndrome and are undergoing gonadal vein embolization.

Not a fit: Patients with pelvic congestion syndrome caused by factors unrelated to venous insufficiency or those who have had prior surgical interventions for PCS may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable data on the effectiveness of gonadal vein embolization in relieving chronic pelvic pain for women suffering from PCS.

How similar studies have performed: Previous studies have indicated that gonadal vein embolization can reduce pain in patients with PCS, suggesting that this approach has shown promise in similar contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Female patients 18 years of age or older
* Meet the clinical and imaging criteria for the diagnosis of PCS and have no contraindications to coil embolization of the gonadal veins.
* Patients who are treated with coil embolization of the gonadal veins in the Interventional Radiology division between October 1, 2018 to October 1, 2019.

Exclusion Criteria:

* Patients less than 18 years of age.
* Patients who are found to have an underlying cause of pelvic congestion syndrome unrelated to venous congestion and insufficiency. This includes, but is not limited to, nutcracker syndrome, or a mass resulting in extrinsic compression of the gonadal veins.
* Patients who have received prior surgical therapy for PCS, including bilateral salpingo-oophorectomy (TAH-BSO), gonadal vein resection, or gonadal vein ligation.

Where this trial is running

Kansas City, Kansas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pelvic Congestive SyndromePelvic Paingonadal vein embolization
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.